Search Results - "Sameera R. Samarakoon"
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Effect of natural curcuminoids‐intercalated layered double hydroxide nanohybrid against Staphylococcus aureus, Pseudomonas aeruginosa, and Enterococcus faecalis: A bactericidal, antibiofilm, and mechanistic study
Published in MicrobiologyOpen (Weinheim) (01-05-2019)“…The study aimed to determine the antibacterial/antibiofilm effect and mechanism of interaction of curcuminoids‐intercalated Mg/Al layered double hydroxide…”
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Isolation of a New Sesquiterpene Lactone From Vernonia Zeylanica (L) Less and its Anti-Proliferative Effects in Breast Cancer Cell Lines
Published in Anti-cancer agents in medicinal chemistry (01-01-2019)“…Vernonia zeylanica (L) less is an endemic plant to Sri Lanka. The present study was designed to isolate potential cytotoxic compound/s from chloroform and…”
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Biological Evaluation of Platinum(II) Sulfonamido Complexes: Synthesis, Characterization, Cytotoxicity, and Biological Imaging
Published in Bioinorganic chemistry and applications (13-09-2022)“…Platinum-based compounds are actively used in clinical trials as anticancer agents. In this study, two novel platinum complexes, (C1 = [PtCl2(N(SO2quin)dpa)],…”
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Vernolactone Promotes Apoptosis and Autophagy in Human Teratocarcinomal (NTERA-2) Cancer Stem-Like Cells
Published in Stem cells international (2019)“…Vernonia zeylanica, is a shrub endemic to Sri Lanka. V. zeylanica has been used in Sri Lankan traditional medicine for the treatment of various diseases and…”
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Anti-diabetic and anti-cancer related health food properties of selected Sri Lankan traditional rice based porridges
Published in Journal of food science and technology (01-10-2022)“…Four Sri Lankan porridges including madathawalu (MWP), kaluheenati (KHP), mixed rice of sudu heenati, goda heenati, masuran, and dikwee (MXP) and special…”
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Synthesis, characterization and biological evaluation of dipicolylamine sulfonamide derivatized platinum complexes as potential anticancer agents
Published in RSC advances (14-05-2021)“…Three new Pt complexes, [PtCl 2 (N(SO 2 (2-nap))dpa)], [PtCl 2 (N(SO 2 (1-nap))dpa)] and [PtCl 2 (N(SO 2 pip)dpa)], containing a rare 8-membered ring were…”
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A molecular-genetics perspective on the systematics of the parthenogenetic flowerpot blindsnake Indotyphlops braminus (Daudin, 1803) (Squamata: Serpentes: Typhlopidae)
Published in Systematics and biodiversity (31-12-2022)“…Sri Lanka has a rich snake diversity, but the island's scolecophidians ('blindsnakes') are poorly understood due to the cryptic, burrowing habits of these…”
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Evaluation of anticancer effects of a pharmaceutically viable extract of a traditional polyherbal mixture against non-small-cell lung cancer cells
Published in Journal of integrative medicine (01-05-2020)“…The present work tested organic solvents to prepare an extract with anticancer properties from a polyherbal mixture containing Nigella sativa (seeds),…”
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A Study on Cytotoxic and Apoptotic Potential of a Triterpenoid Saponin (3-O-α-L-Arabinosyl Oleanolic Acid) Isolated from Schumacheria castaneifolia Vahl in Human Non-Small-Cell Lung Cancer (NCI-H292) Cells
Published in BioMed research international (01-01-2017)“…Lung cancer is the major cause of cancer death among men. A number of natural compounds have proven to be useful in the treatmet of lung cancer. This study was…”
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Factors affecting iron absorption and the role of fortification in enhancing iron levels
Published in Nutrition bulletin (01-12-2023)“…Abstract Iron is an important micronutrient required for a number of biological processes including oxygen transport, cellular respiration, the synthesis of…”
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Cytotoxic and Apoptotic Effects of Govaniadine Isolated from Corydalis govaniana Wall. Roots on Human Breast Cancer (MCF-7) Cells
Published in BioMed research international (01-01-2018)“…Current breast cancer therapies have limitations in terms of increased drug resistance resulting in short-term efficacy, thus demanding the discovery of new…”
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An efficient and high-yielding method for extraction and purification of linamarin from Cassava; in vitro biological evaluation
Published in Natural product research (02-11-2021)“…During the last three decades, studies of linamarin extracted from cassava have received increased attention due to the presence of high cyanogenic compounds…”
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The Genome of Setaria digitata: A Cattle Nematode Closely Related to Human Filarial Parasites
Published in Genome biology and evolution (01-02-2020)“…Abstract Here we present the draft genome sequence of Setaria digitata, a parasitic nematode affecting cattle. Due to its similarity to Wuchereria bancrofti,…”
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Modulation of apoptosis in human hepatocellular carcinoma (HepG2 cells) by a standardized herbal decoction of Nigella sativa seeds, Hemidesmus indicus roots and Smilax glabra rhizomes with anti- hepatocarcinogenic effects
Published in BMC complementary and alternative medicine (29-03-2012)“…A standardized poly-herbal decoction of Nigella sativa seeds, Hemidesmus indicus roots and Smilax glabra rhizomes used traditionally in Sri Lanka for cancer…”
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Anti-hepatocarcinogenic and Anti-oxidant Effects of Mangrove Plant Scyphiphora hydrophyllacea
Published in Pharmacognosy Magazine (01-01-2017)“…is a shrub mangrove plant of the family Rubiaceae and not yet been studied for anti-hepatocarcinogenic effects. We investigated possible…”
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In vitro Cytotoxic and Antioxidant Activity of Leaf Extracts of Mangrove Plant, Phoenix paludosa Roxb
Published in Tropical journal of pharmaceutical research (01-01-2016)“…Purpose: To investigate the anti-proliferative and antioxidant potentials of four different solvent extracts of Phoenix paludosa Roxb leaves. Methods: Four…”
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Anti-Inflammatory Activity Is a Possible Mechanism by Which the Polyherbal Formulation Comprised of Nigella sativa (Seeds), Hemidesmus indicus (Root), and Smilax glabra (Rhizome) Mediates Its Antihepatocarcinogenic Effects
Published in Evidence-based complementary and alternative medicine (01-01-2012)“…The present study investigated the anti-inflammatory effects of a polyherbal decoction comprised of Nigella sativa, Hemidesmus indicus, and Smilax glabra in…”
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A comparison of the cytotoxic potential of standardized aqueous and ethanolic extracts of a polyherbal mixture comprised of Nigella sativa (seeds), Hemidesmus indicus (roots) and Smilax glabra (rhizome)
Published in Pharmacognosy research (01-11-2010)“…A decoction (hot-water extract) comprised of Nigella sativa (seeds), Hemidesmus indicus (roots), and Smilax glabra (rhizome) has been reported to prevent…”
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Cytotoxic and Apoptotic Effect of the Decoction of the Aerial Parts of Flueggea leucopyrus on Human Endometrial Carcinoma (AN3CA) Cells
Published in Tropical journal of pharmaceutical research (12-09-2014)“…Purpose: To evaluate the anti-cancer potentials of a decoction of Flueggea leucopyrus (Willd.) on human endometrial carcinoma (AN3CA) cells. Methods: Decoction…”
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Pseudophilautus dilmah, a new species of shrub frog (Amphibia: Anura: Rhacophoridae) from a threatened habitat Loolkandura in Sri Lanka
Published in Journal of threatened taxa (26-04-2015)“…A new species of shrub frog Pseudophilautus dilmah is described from the Central Hills of Sri Lanka. This unique species is distinguished from all the other…”
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