Search Results - "Sameer Kumar, V.B."

Horizontal transfer of miR-106a/b from cisplatin resistant hepatocarcinoma cells can alter the sensitivity of cervical cancer cells to cisplatin by Raji, Grace R., Sruthi, T.V., Edatt, Lincy, Haritha, K., Sharath Shankar, S., Sameer Kumar, V.B.

“…Recent studies indicate that horizontal transfer of genetic material can act as a communication tool between heterogenous populations of tumour cells, thus…”
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Endothelial cell response to lactate: Implication of PAR modification of VEGF by Kumar, V.B. Sameer, Viji, R.I., Kiran, M.S., Sudhakaran, P.R.

“…Angiogenesis, the process of formation of new blood vessels from pre‐existing one, occurs in many physiological and pathological conditions, most of which are…”
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Role of microRNA, bta-miR-375 in Immune Sturdiness of Vechur: The Native Cattle Breed of Kerala, India by P. D., Divya, M., Shynu, K.K., Jayavardhanan, R., Uma, T.V., Aravindakshan, G., Radhika, V.B., Sameer kumar, Asaf, Muhasin, Sebastian, Renjith

“…In the present study, next generation sequencing was employed to identify and explore the differential expression profiles of microRNAs (miRNAs) in peripheral…”
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Modulation of angiogenic factors by ursolic acid by Kiran, M.S., Viji, R.I., Sameer Kumar, V.B., Sudhakaran, P.R.

“…Investigations were carried out to understand the molecular basis of the effect of ursolic acid on angiogenesis by analysing its effects on the expression of…”
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Individual and simultaneous electrochemical determination of metanil yellow and curcumin on carbon quantum dots based glassy carbon electrode by Shereema, Rayammarakkar M., Rao, Talasila P., Sameer Kumar, V.B., Sruthi, T.V., Vishnu, R., Prabhu, G.R.D., Sharath Shankar, S.

“…Adulteration of medicinally valuable curcumin (CU) with harmful chemicals as metanil yellow (MY) in recent years have demanded for quick detection techniques…”
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Temporal relationship between MMP production and angiogenic process in HUVECs by Kiran, M.S., Sameer Kumar, V.B., Viji, R.I., Sudhakaran, P.R.

“…Alterations in both cell–cell and cell–matrix interactions are associated with the activation of endothelial cells that initiate angiogenesis. Cell–matrix…”
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Tumour generated exosomal miRNAs: A major player in tumour angiogenesis by Kumar, V B Sameer, Anjali, K

“…One of the major reasons for the non-effectiveness of anticancer therapeutics designed to target tumour angiogenesis is the involvement of multiple layers of…”
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Horizontal transfer of miR‐23a from hypoxic tumor cell colonies can induce angiogenesis by Sruthi, T. V., Edatt, Lincy, Raji, Grace R., Kunhiraman, Haritha, Shankar, Sharath S., Shankar, Vandana, Ramachandran, Vishnu, Poyyakkara, Aswini, Kumar, Sameer V. B.

“…Neo vessel formation by angiogenesis is an important event during many pathological conditions including cancer, where it is indispensable for tumor growth and…”
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ER stress mediated regulation of miR23a confer Hela cells better adaptability to utilize glycolytic pathway by Poyyakkara, Aswini, Raji, Grace R., Kunhiraman, Haritha, Edatt, Lincy, Kumar, Sameer V.B.

“…Cancer cells exhibit increased dependency on aerobic glycolysis, a phenomenon referred as the “Warburg effect” and therefore, blocking glycolysis by using…”
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Identification and stability analysis of potential ADP-ribose modification sites on vascular endothelial growth factor (VEGF) through molecular dynamics simulation by Sreelakshmi, Kalayakkattil, Hemavathi, Kadabagere Narayanaswamy, Raju, Rajesh, Sameer, Kumar V B, Keshava Prasad, Thottethodi Subramanya, Sudhakaran, Perumana R, Abhinand, Chandran S

“…Post-translational modifications (PTMs) are crucial covalent processes that alter protein properties, achieved through proteolytic cleavage or addition of…”
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MicroRNA106a regulates matrix metalloprotease 9 in a sirtuin‐1 dependent mechanism by Edatt, Lincy, Maurya, Ashutosh K., Raji, Grace, Kunhiraman, Haritha, Kumar, Sameer V. B.

“…Cellular migration is important during many physiological as well as pathological conditions and is regulated very tightly by an intricate network of signaling…”
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The tumour suppressor LKB1 regulates myelination through mitochondrial metabolism by Pooya, Shabnam, Liu, Xiaona, Kumar, V.B. Sameer, Anderson, Jane, Imai, Fumiyasu, Zhang, Wujuan, Ciraolo, Georgianne, Ratner, Nancy, Setchell, Kenneth D.R., Yoshida, Yutaka, Jankowski, Michael P., Dasgupta, Biplab

“…A prerequisite to myelination of peripheral axons by Schwann cells (SCs) is SC differentiation, and recent evidence indicates that reprogramming from a…”
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2‐Deoxy Glucose Modulates Expression and Biological Activity of VEGF in a SIRT‐1 Dependent Mechanism by Kunhiraman, Haritha, Edatt, Lincy, Thekkeveedu, Sruthi, Poyyakkara, Aswini, Raveendran, Viji, Kiran, Manikantan Syamala, Sudhakaran, Perumana, Kumar, Sameer V.B.

“…ABSTRACT Reprogramming of energy metabolism particularly switching over of cells to aerobic glycolysis leading to accumulation of lactate is a hallmark of…”
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2-Deoxy Glucose Modulates Expression and Biological Activity of VEGF in a SIRT-1 Dependent Mechanism: R EGULATION OF VEGF BY 2-DG by Kunhiraman, Haritha, Edatt, Lincy, Thekkeveedu, Sruthi, Poyyakkara, Aswini, Raveendran, Viji, Kiran, Manikantan Syamala, Sudhakaran, Perumana, Kumar, Sameer V.B.

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Opposing effects of curcuminoids on serum stimulated and unstimulated angiogenic response by Kiran, M.S., Kumar, V.B. Sameer, Viji, R.I., Sherin, G.T., Rajasekharan, K.N., Sudhakaran, P.R.

“…Curcumin is known to be a potent wound healer. Despite this, studies on curcumin using certain model systems have shown it to be anti‐angiogenic. Results of…”
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Angiogenic response of endothelial cells to heparin-binding domain of fibronectin by Viji, R.I., Kumar, V.B. Sameer, Kiran, M.S., Sudhakaran, P.R.

“…Interaction of endothelial cells with cell-binding domain of fibronectin through integrin receptors is important in the process of angiogenesis. The present…”
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Modulation of cyclooxygenase in endothelial cells by fibronectin: Relevance to angiogenesis by Viji, R.I., Kumar, V.B. Sameer, Kiran, M.S., Sudhakaran, P.R.

“…Cyclooxygenases (COX), which catalyze the formation of prostaglandins (PGs), have been implicated in angiogenesis. Adhesion of endothelial cells (ECs) to…”
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Negative modulation of eNOS by laminin involving post-translational phosphorylation by Kumar, V.B. Sameer, Viji, R.I., Kiran, M.S., Sudhakaran, P.R.

“…Nitric oxide (NO) regulates the vascular tone, and influences survival and apoptosis of endothelial cells (ECs). NO is produced by nitric oxide synthase (NOS)…”
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Modulation of expression of LDH isoenzymes in endothelial cells by laminin: Implications for angiogenesis by Kumar, V.B. Sameer, Viji, R.I., Kiran, M.S., Sudhakaran, P.R.

“…Endothelial cell (EC) matrix interaction is critical in angiogenesis. Although matrix components can regulate the process of angiogenesis by acting as a…”
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