Search Results - "Sambyal, Vasudha"
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Association of VEGF-2549I/D promoter polymorphism with gastrointestinal tract cancer risk: a meta-analysis
Published in Egyptian Journal of Medical Human Genetics (01-12-2024)“…Background Gastrointestinal tract (GIT) cancers are complex disorders affecting millions of people worldwide. The vascular endothelial growth factor (VEGF)…”
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2
Potential carcinogenic and non-carcinogenic health hazards of metal(loid)s in food grains
Published in Environmental science and pollution research international (01-05-2020)“…Metal(loid) contamination of vital food grains such as wheat and rice is a very serious problem throughout the world because consumption of such contaminated…”
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3
Candidate genes for infertility: an in-silico study based on cytogenetic analysis
Published in BMC medical genomics (02-08-2022)“…The cause of infertility remains unclear in a significant proportion of reproductive-age couples who fail to conceive naturally. Chromosomal aberrations have…”
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4
Association of Vascular Endothelial Growth Factor (VEGF) and Mouse Model Minute 2 (MDM2) Polymorphisms With Diabetic Retinopathy in a Northwest Indian Population: A Case-Control Study
Published in Curēus (Palo Alto, CA) (23-06-2024)“…Diabetic retinopathy (DR), a microvascular complication of type 2 diabetes (T2D), results from complex interactions of genetic and environmental factors…”
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5
Association of VEGFR1, VEGFR2 and VEGFR3 polymorphisms with esophageal cancer risk: a case-control study
Published in Egyptian Journal of Medical Human Genetics (09-08-2024)“…Background Esophageal cancer is the eleventh most common cancer and is the seventh leading cause of mortality worldwide. Vascular endothelial growth factor…”
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6
Impact of VEGFA promoter polymorphisms on esophageal cancer risk in North-West Indians: a case-control study
Published in Genes & genomics (01-08-2022)“…Background Angiogenesis play a critical role in the development and progression of tumors in solid tumors. Vascular endothelial growth factor (VEGF) is one of…”
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Association of VEGF haplotypes with breast cancer risk in North-West Indians
Published in BMC medical genomics (24-08-2021)“…Angiogenesis is a complex and coordinated process regulated by different growth factors and is one of the hallmark features of cancer. VEGF is one of the most…”
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8
Copy number variations in male breast cancer
Published in Journal of cancer research and therapeutics (01-07-2023)“…Common copy number variations often contain cancer-related genes and are likely to play a role in carcinogenesis. Different mechanisms of tumorigenesis are…”
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9
Linkage disequilibrium and haplotypes of five TP53 polymorphisms in oesophageal cancer patients
Published in Journal of genetics (01-12-2020)“…The aim of present study was to evaluate the linkage disequilibrium (LD) of p.R72P, PIN3 Ins16bp, p.P47S, p.R213R and r.13494g>a polymorphism of TP53 and their…”
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10
In silico pathway analysis based on chromosomal instability in breast cancer patients
Published in BMC medical genomics (09-11-2020)“…Complex genomic changes that arise in tumors are a consequence of chromosomal instability. In tumor cells genomic aberrations disrupt core signaling pathways…”
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11
Screening of BRCA1 variants c.190T>C, 1307delT, g.5331G>A and c.2612C>T in breast cancer patients from North India
Published in Genetics and molecular biology (01-01-2020)“…The polymorphic variants of BRCA1, which lead to amino acid substitutions, have a known pathogenic role in breast cancer. The present study investigated in…”
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12
Comparison of demographic, socioeconomic, and lifestyle determinants in infertile and fertile males and females from two big cities of Punjab
Published in BLDE university journal of health sciences (01-07-2022)“…BACKGROUND: Infertility is an apparent failure of a couple to conceive. The demographic, socioeconomic, and lifestyle determinants in infertility and its…”
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13
No Association between the CCR5Δ32 Polymorphism and Sporadic Esophageal Cancer in Punjab, North-West India
Published in Asian Pacific journal of cancer prevention : APJCP (2015)“…Background: Chemokines and their receptors influence carcinogenesis and cysteine-cysteine chemokine receptor 5 (CCR5) directs spread of cancer to other…”
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14
Association of the -2518 A/G Polymorphism of MCP-1 with Breast Cancer in Punjab, North-West India
Published in Asian Pacific journal of cancer prevention : APJCP (2015)“…Background: Monocyte chemoattractant protein-1 (MCP-1) is a major chemokine thought to be responsible for monocyte and T-lymphocyte recruitment in acute…”
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15
Plasma monocyte chemoattractant protein-1 as risk marker in type 2 diabetes mellitus and coronary artery disease in North Indians
Published in Diabetes & vascular disease research (01-10-2009)“…The chemokine monocyte chemoattractant protein-1 (MCP-1) is implicated in chronic inflammation, insulin resistance and atherosclerosis. The present study was…”
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Association of +405C>G and +936C>T Polymorphisms of the Vascular Endothelial Growth Factor Gene with Sporadic Breast Cancer in North Indians
Published in Asian Pacific journal of cancer prevention : APJCP (2014)“…Background: Vascular endothelial growth factor (VEGF), an endothelial cell specific mitogen, has been implicated as a critical factor influencing tumor related…”
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17
Analysis of TP53 Polymorphisms in North Indian Sporadic Esophageal Cancer Patients
Published in Asian Pacific journal of cancer prevention : APJCP (2014)“…Background: To investigate the relationship of five TP53 polymorphisms (p.P47S, p.R72P, PIN3 ins16bp, p.R213R and r.13494g>a) with the esophageal cancer (EC)…”
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18
No Association of Hypoxia Inducible Factor-1α Gene Polymorphisms with Breast Cancer in North-West Indians
Published in Asian Pacific journal of cancer prevention : APJCP (2014)“…Background: Hypoxia inducible factor-1 alpha (HIF-$1{\alpha}$) is the key regulator of cellular responses to hypoxia and plays a central role in tumour growth…”
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TP53 Polymorphisms in Sporadic North Indian Breast Cancer Patients
Published in Asian Pacific journal of cancer prevention : APJCP (2014)“…Background: The purpose of this study was to evaluate the potential association of five (p.P47S, p.R72P, PIN3 Ins16bp, p.R213R and r.13494g>a) polymorphisms of…”
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20
XRCC1 Polymorphisms p.Arg194Trp, p.Arg280His, and p.Arg399Gln, Polycyclic Aromatic Hydrocarbons, and Infertility: A Case-Control and In Silico Study
Published in Biochemical genetics (21-03-2024)“…XRCC1 is involved in repair of single-strand breaks generated by mutagenic exposure. Polymorphisms within XRCC1 affect its ability to efficiently repair DNA…”
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