Liver Disease and Treatment Needs of Asymptomatic Persons Living With Hepatitis B in Senegal

Abstract The prevalence of active hepatitis B among asymptomatic persons remains unclear in Africa. Of 1206 newly diagnosed persons in Senegal, 12.3% had significant fibrosis and 31.3% had hepatitis B virus (HBV) DNA levels >2000 IU/mL. Overall, 128 (12.9%) were eligible for antiviral therapy. Ge...

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Published in:Open forum infectious diseases Vol. 9; no. 11; p. ofac558
Main Authors: Ramírez Mena, Adrià, Thioubou, Mame Aissé, Diallo, Kalilou, Tine, Judicaël, Ngom, Ndeye Fatou, Fortes, Louise, Ndiaye, Kiné, Karasi, Jean-Claude, Seguin-Devaux, Carole, Goedertz, Henri, Diouf, Daouda, Seydi, Moussa, Sambou, Benjamin Amaye, Arendt, Vic, Wandeler, Gilles, Manga, Noël Magloire
Format: Journal Article
Language:English
Published: US Oxford University Press 01-11-2022
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Summary:Abstract The prevalence of active hepatitis B among asymptomatic persons remains unclear in Africa. Of 1206 newly diagnosed persons in Senegal, 12.3% had significant fibrosis and 31.3% had hepatitis B virus (HBV) DNA levels >2000 IU/mL. Overall, 128 (12.9%) were eligible for antiviral therapy. Generalized HBV screening allowed the identification of a large population requiring HBV care.
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G. W. and N. M. M. contributed equally to this work.
Potential conflicts of interest. The authors declare no conflict of interest. The funders had no role in the design of the study; in the collection, analyses, or interpretation of data; in the writing of the manuscript, or in the decision to publish the results.
ISSN:2328-8957
2328-8957
DOI:10.1093/ofid/ofac558