Search Results - "Samaritoni, J. Geno"

Preparation and Use of a General Solid-Phase Intermediate to Biomimetic Scaffolds and Peptide Condensations by Samaritoni, J Geno, Martynow, Jacek G, O'Donnell, Martin J, Scott, William L

“…The Distributed Drug Discovery (D3) program develops simple, powerful, and reproducible procedures to enable the distributed synthesis of large numbers of…”
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Unexpected Hydrolytic Instability of N‑Acylated Amino Acid Amides and Peptides by Samaritoni, J. Geno, Copes, Alexus T, Crews, DeMarcus K, Glos, Courtney, Thompson, Andre L, Wilson, Corydon, O’Donnell, Martin J, Scott, William L

“…Remote amide bonds in simple N-acyl amino acid amide or peptide derivatives 1 can be surprisingly unstable hydrolytically, affording, in solution, variable…”
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Globally Distributed Drug Discovery of New Antibiotics: Design and Combinatorial Synthesis of Amino Acid Derivatives in the Organic Chemistry Laboratory by Dounay, Amy B, O’Donnell, Martin J, Samaritoni, J. Geno, Popiolek, Lukasz, Schirch, Douglas, Biernasiuk, Anna, Malm, Anna, Lamb, Isaac W, Mudrack, Kristen, Rivera, Daniel G, Ojeda, Gerardo M, Scott, William L

“…An experiment for the synthesis of N-acyl derivatives of natural amino acids has been developed as part of the Distributed Drug Discovery (D3) program…”
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Multi-Institution Research and Education Collaboration Identifies New Antimicrobial Compounds by Fuller, Amelia A, Dounay, Amy B, Schirch, Douglas, Rivera, Daniel G, Hansford, Karl A, Elliott, Alysha G, Zuegg, Johannes, Cooper, Matthew A, Blaskovich, Mark A. T, Hitchens, Jacob R, Burris-Hiday, Sarah, Tenorio, Kristiana, Mendez, Yanira, Samaritoni, J. Geno, O’Donnell, Martin J, Scott, William L

“…New antibiotics are urgently needed to address increasing rates of multidrug resistant infections. Seventy-six diversely functionalized compounds, comprising…”
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Distributed Drug Discovery: Advancing Chemical Education through Contextualized Combinatorial Solid-Phase Organic Laboratories by Scott, William L, Denton, Ryan E, Marrs, Kathleen A, Durrant, Jacob D, Samaritoni, J. Geno, Abraham, Milata M, Brown, Stephen P, Carnahan, Jon M, Fischer, Lindsey G, Glos, Courtney E, Sempsrott, Peter J, O’Donnell, Martin J

“…The Distributed Drug Discovery (D3) program trains students in three drug discovery disciplines (synthesis, computational analysis, and biological screening)…”
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A solid-phase synthetic route to N-acylated α-alkyl-d,l-homoserine lactones by Ali, Ahmed I.M., O'Donnell, Martin J., Scott, William L., Samaritoni, J. Geno

“…[Display omitted] •Novel, acylated homoserine lactones with quaternized alpha position are now accessible.•Unnatural Peptide Synthesis (UPS) utilized to…”
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PREPARATION OF 3-BROMO-2-(NITROMETHYLENE)PYRROLIDINE AND 3-BROMO-N-METHYL-l-NITRO-l-BUTEN-2-AMINE by Samaritoni, J. Geno

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Synthesis and chemistry of N-arylated pyrano[2,3-c]pyrazoles by Samaritoni, J. Geno, Thornburgh, Scott, Graupner, Paul R., Cooper, David H.

“…Novel N2‐arylated pyrano[2,3‐c]pyrazol‐6‐ones 2 can be prepared in a selective manner by generating the anion of 1 (RH) with lithium hexamethyldisilazide in…”
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