Search Results - "Samarasinghe, Buddhini"
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Identifying stakeholder preferences for communicating impact from medical research: a mixed methods study
Published in BMC health services research (29-10-2024)“…Documentation of research outcomes using impact case studies (ICS) is increasingly required to demonstrate the wider societal benefits of research. However,…”
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Factors affecting susceptibility to RNA interference in Haemonchus contortus and in vivo silencing of an H11 aminopeptidase gene
Published in International journal for parasitology (2011)“…[Display omitted] ► Robust RNA interference (RNAi) of some genes occurs in Haemonchus contortus. ► Site of gene expression influences silencing. ► Can identify…”
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Heat shock factor 1 confers resistance to Hsp90 inhibitors through p62/SQSTM1 expression and promotion of autophagic flux
Published in Biochemical pharmacology (01-02-2014)“…Heat shock protein 90 (Hsp90) has an important role in many cancers. Biochemical inhibitors of Hsp90 are in advanced clinical development for the treatment of…”
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Ups and downs of RNA interference in parasitic nematodes
Published in Experimental parasitology (01-09-2012)“…[Display omitted] ► Parasitic nematode genes vary in susceptibility to RNAi. ► Site of gene expression influences silencing in Haemonchus contortus. ► In vivo…”
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Toxoplasmosis awareness, seroprevalence and risk behavior among pregnant women in the Gampaha district, Sri Lanka
Published in Pathogens and global health (01-03-2016)“…Background: Primary gestational toxoplasmosis can be transmitted to the fetus with deleterious effects on the pregnancy. There is very little information…”
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Journal Article -
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Abstract 2261: Heat-shock and autophagy in cancer: Novel role for DGK iota
Published in Cancer research (Chicago, Ill.) (15-04-2012)“…Abstract Autophagy is a cellular process by which damaged proteins, protein aggregates, and organelles are sequestered by lysosome-like compartments and…”
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Journal Article -
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Analysis of rna interference in the parasitic nematode haemonchus contortus
Published 01-01-2010“…Parasitic nematode infections worldwide cause a significant impact on human health, as well as economic and welfare losses to the animal and agriculture…”
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Dissertation