Search Results - "Samarasekera, Thanya"

Islet amyloid formation is an important determinant for inducing islet inflammation in high-fat-fed human IAPP transgenic mice by Meier, Daniel T., Morcos, Mary, Samarasekera, Thanya, Zraika, Sakeneh, Hull, Rebecca L., Kahn, Steven E.

“…Aims/hypothesis Amyloid deposition and inflammation are characteristic of islet pathology in type 2 diabetes. The aim of this study was to determine whether…”
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One year of sitagliptin treatment protects against islet amyloid-associated β-cell loss and does not induce pancreatitis or pancreatic neoplasia in mice by Aston-Mourney, Kathryn, Subramanian, Shoba L, Zraika, Sakeneh, Samarasekera, Thanya, Meier, Daniel T, Goldstein, Lynn C, Hull, Rebecca L

“…The dipeptidyl peptidase-4 (DPP-4) inhibitor sitagliptin is an attractive therapy for diabetes, as it increases insulin release and may preserve β-cell mass…”
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Determination of Optimal Sample Size for Quantification of β-Cell Area, Amyloid Area and β-Cell Apoptosis in Isolated Islets by Meier, Daniel T., Entrup, Leon, Templin, Andrew T., Hogan, Meghan F., Samarasekera, Thanya, Zraika, Sakeneh, Boyko, Edward J., Kahn, Steven E.

“…Culture of isolated rodent islets is widely used in diabetes research to assess different endpoints, including outcomes requiring histochemical staining. As…”
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