Search Results - "Samanta, Dibyendu"
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Nectin family of cell-adhesion molecules: structural and molecular aspects of function and specificity
Published in Cellular and molecular life sciences : CMLS (01-02-2015)“…Cell–cell adhesive processes are central to the physiology of multicellular organisms. A number of cell surface molecules contribute to cell–cell adhesion, and…”
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Tracing the evolution of nectin and nectin-like cell adhesion molecules
Published in Scientific reports (10-06-2020)“…Nectin and nectin-like cell adhesion molecules (collectively referred as nectin family henceforth) are known to mediate cell-cell adhesion and related…”
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Structure of Nectin-2 reveals determinants of homophilic and heterophilic interactions that control cell–cell adhesion
Published in Proceedings of the National Academy of Sciences - PNAS (11-09-2012)“…Nectins are members of the Ig superfamily that mediate cell-cell adhesion through homophilic and heterophilic interactions. We have determined the crystal…”
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A Possible Role of the Full-Length Nascent Protein in Post-Translational Ribosome Recycling
Published in PloS one (18-01-2017)“…Each cycle of translation initiation in bacterial cell requires free 50S and 30S ribosomal subunits originating from the post-translational dissociation of 70S…”
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Protein Folding by Domain V of Escherichia coli 23S rRNA: Specificity of RNA-Protein Interactions
Published in Journal of Bacteriology (01-05-2008)“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Structural and functional characterization of a single-chain peptide–MHC molecule that modulates both naive and activated CD8+ T cells
Published in Proceedings of the National Academy of Sciences - PNAS (16-08-2011)“…Peptide–MHC (pMHC) multimers, in addition to being tools for tracking and quantifying antigen-specific T cells, can mediate downstream signaling after T-cell…”
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Emerging roles of the nectin family of cell adhesion molecules in tumour-associated pathways
Published in Biochimica et biophysica acta. Reviews on cancer (01-12-2021)“…Tumour cells achieve maximum survival by modifying cellular machineries associated with processes such as cell division, migration, survival, and apoptosis,…”
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Identification and Characterization of Novel Macromolecular Assemblies Responsible for Cell Adhesion
Published in The FASEB journal (01-05-2022)“…Cadherins and nectins are cell surface glycoproteins that function as cell adhesion molecules (CAMs) to drive the adhesion of cells and thereby organize them…”
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Cadherin‐mediated host–pathogen interactions
Published in Cellular microbiology (01-05-2021)“…Cell adhesion molecules mediate cell‐to‐cell and cell‐to‐matrix adhesions and play an immense role in a myriad of physiological processes during the growth and…”
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Molecular and structural basis of TIGIT: Nectin-4 interaction, a recently discovered pathway crucial for cancer immunotherapy
Published in Biochemical and biophysical research communications (15-10-2023)“…TIGIT (T cell immunoglobulin and ITIM domain) is an inhibitory receptor expressed on T and NK cells that interact with cell surface glycoprotein belonging to…”
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An evolutionarily conserved charged residue dictates the specificity of heterophilic interactions among nectins
Published in Biochemical and biophysical research communications (01-01-2021)“…Nectins are a family of four cell surface glycoproteins belonging to the immunoglobulin superfamily that mediate cell-cell adhesion and associated signalling…”
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A nanobody based ultrasensitive electrochemical biosensor for the detection of soluble CTLA-4 –A candidate biomarker for cancer development and progression
Published in Biosensors & bioelectronics (15-12-2023)“…A soluble isoform of cytotoxic T-lymphocyte–associated antigen 4 (CTLA-4) has been found in the serum of healthy individuals and alterations in its expression…”
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Molecular mimicry of host short linear motif-mediated interactions utilised by viruses for entry
Published in Molecular biology reports (01-05-2023)“…Viruses are obligate intracellular parasites that depend on host cellular machinery for performing even basic biological functions. One of the many ways they…”
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Heterophilic recognition between E-cadherin and N-cadherin relies on same canonical binding interface as required for E-cadherin homodimerization
Published in Archives of biochemistry and biophysics (30-09-2022)“…Cadherins are a family of cell surface glycoproteins that mediate Ca2+-dependent cell to cell adhesion. They organize to form large macromolecular assemblies…”
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In silico and in vitro characterization of the mycobacterial protein Ku to unravel its role in non-homologous end-joining DNA repair
Published in International journal of biological macromolecules (01-10-2024)“…Non-homologous end-joining (NHEJ) stands as a pivotal DNA repair pathway crucial for the survival and persistence of Mycobacterium tuberculosis (Mtb) during…”
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Molecular Crosstalk Between Adherens Junction Proteins, E-cadherin and Nectin-4
Published in Journal of molecular biology (15-09-2024)“…[Display omitted] •Cadherins and nectins assemble to build the adherens junction.•E-cadherin and nectin-4 directly interact as revealed by surface plasmon…”
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Immunoglobulin-fold containing bacterial adhesins: molecular and structural perspectives in host tissue colonization and infection
Published in FEMS microbiology letters (04-02-2021)“…ABSTRACT Immunoglobulin (Ig) domains are one of the most widespread protein domains encoded by the human genome and are present in a large array of proteins…”
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Activation and differentiation of cognate T cells by a dextran‐based antigen‐presenting system for cancer immunotherapy
Published in European journal of immunology (01-12-2023)“…Immunotherapeutic modulation of antigen‐specific T‐cell responses instead of the whole repertoire helps avoid immune‐related adverse events. We have developed…”
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Structural Characterization of LpqH (19 kDa surface antigen), an Immunomodulatory Lipoprotein of Mycobacterium tuberculosis
Published in The FASEB journal (01-05-2022)“…Tuberculosis, caused by Mycobacterium tuberculosis, is predominantly a disease of the lungs acquired by inhaling mycobacteria from infected individuals via…”
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Molecular and structural bases of interaction between extracellular domains of nectin‐2 and N‐cadherin
Published in Proteins, structure, function, and bioinformatics (01-11-2018)“…Cell adhesion molecules such as nectins and cadherins play important role in the formation of adherens junction. While nectins interact through their…”
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