Search Results - "Samadi, Nasser"

Exosomes: from carcinogenesis and metastasis to diagnosis and treatment of gastric cancer by Kahroba, Houman, Hejazi, Mohammad Saeid, Samadi, Nasser

“…Exosomes represent an important group of extracellular vesicles with a defined size between 40 and 150 nm and cup-shaped construction which have a pivotal role…”
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The Role of Nrf2 signaling in cancer stem cells: From stemness and self-renewal to tumorigenesis and chemoresistance by Kahroba, Houman, Shirmohamadi, Masoud, Hejazi, Mohammad Saeid, Samadi, Nasser

“…Cancer stem cells (CSCs) are subpopulation of tumor mass with exclusive abilities in self-renewing, stemness maintaining, and differentiation into the various…”
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The potential therapeutic effect of melatonin on human ovarian cancer by inhibition of invasion and migration of cancer stem cells by Akbarzadeh, Maryam, Movassaghpour, Ali Akbar, Ghanbari, Hossein, Kheirandish, Maryam, Fathi Maroufi, Nazila, Rahbarghazi, Reza, Nouri, Mohammad, Samadi, Nasser

“…There is an urgent need to identify targeting molecules to control invasion and metastasis in cancer patients. We first isolated cancer stem cells (CSCs) from…”
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Contradictory roles of Nrf2/Keap1 signaling pathway in cancer prevention/promotion and chemoresistance by Jeddi, Farhad, Soozangar, Narges, Sadeghi, Mohammad Reza, Somi, Mohammad Hossein, Samadi, Nasser

“…•Nrf2 exerts cancer-preventive activity through induction of cytoprotective genes.•Under a deleterious environment, Nrf2 elevates the survival rate of tumor…”
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Current approaches in identification and isolation of cancer stem cells by Akbarzadeh, Maryam, Maroufi, Nazila Fathi, Tazehkand, Abbas Pirpour, Akbarzadeh, Moloud, Bastani, Sepideh, Safdari, Reza, Farzane, Ali, Fattahi, Amir, Nejabati, Hamid Reza, Nouri, Mohammad, Samadi, Nasser

“…Cancer stem cells (CSCs) are tumor cells with initiating ability, self‐renewal potential, and intrinsic resistance to conventional therapeutics. Efficient…”
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Doxorubicin Changes Bax /Bcl-xL Ratio, Caspase-8 and 9 in Breast Cancer Cells by Sharifi, Simin, Barar, Jaleh, Hejazi, Mohammad Saeid, Samadi, Nasser

“…Purpose: Doxorubicin is administrated as a single agent in first-line therapy of breast cancer to induce apoptosis in tumor cells. Bax, Bcl-xL, Caspase-8 and 9…”
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Potential roles and prognostic significance of exosomes in cancer drug resistance by Mostafazadeh, Mostafa, Samadi, Nasser, Kahroba, Houman, Baradaran, Behzad, Haiaty, Sanya, Nouri, Mohammad

“…Drug resistance is a major impediment in cancer therapy which strongly reduces the efficiency of anti-cancer drugs. Exosomes are extracellular vesicles with…”
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Epigenetic alterations in chronic disease focusing on Behçet’s disease: Review by Alipour, Shahriar, Nouri, Mohammad, Sakhinia, Ebrahim, Samadi, Nasser, Roshanravan, Neda, Ghavami, Abed, Khabbazi, Alireza

“…Abstract Objective ‘Epigenetics’ is specified as the inheritable changes in gene expression with no alterations in DNA sequences. Epigenetics is a rapidly…”
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The role of Nrf2-Keap1 axis in colorectal cancer, progression, and chemoresistance by Sadeghi, Mohammad Reza, Jeddi, Farhad, Soozangar, Narges, Somi, Mohammad Hossein, Samadi, Nasser

“…Colorectal cancer is the third common cancer after lung and genital cancers worldwide with more than 1.2 million new cases diagnosed annually. Although…”
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Hypermethylation of IL‐10 gene is responsible for its low mRNA expression in Behçet's disease by Alipour, Shahriar, Nouri, Mohammad, Khabbazi, Alireza, Samadi, Nasser, Babaloo, Zohreh, Abolhasani, Somayeh, Farhadi, Jafar, Roshanravan, Neda, Jadideslam, Golamreza, Sakhinia, Ebrahim

“…Interleukin‐10 (IL‐10), produced generally by monocyte, T helper type 2 (Th2), and regulatory T cells (Treg), plays a central role in controlling inflammatory…”
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The potential impact of trigonelline loaded micelles on Nrf2 suppression to overcome oxaliplatin resistance in colon cancer cells by Pirpour Tazehkand, Abbas, Salehi, Roya, Velaei, Kobra, Samadi, Nasser

“…Nuclear factor erythroid 2-related factor 2 (Nrf2) has a pivotal role in promoting chemoresistance by regulation of antioxidants and detoxification enzymes…”
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Peroxisome Proliferator-Activated Receptors and their Ligands in Cancer Drug- Resistance: Opportunity or Challenge by Yousefi, Bahman, Zarghami, Nosratollah, Samadi, Nasser, Majidinia, Maryam

“…Development of resistance in cancer cells results in a high failure rate in cancer chemotherapy in the clinic. Therefore, investigating the mechanisms by which…”
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Balaglitazone reverses P-glycoprotein-mediated multidrug resistance via upregulation of PTEN in a PPARγ-dependent manner in leukemia cells by Yousefi, Bahman, Azimi, Ako, Majidinia, Maryam, Shafiei-Irannejad, Vahid, Badalzadeh, Reza, Baradaran, Behzad, Zarghami, Nosratollah, Samadi, Nasser

“…Multidrug resistance in tumor cells is still a big challenge in cancer treatment. Therefore, identification ofsafe and effective multidrug resistance–reversing…”
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Formulation of Stattic as STAT3 inhibitor in nanostructured lipid carriers (NLCs) enhances efficacy of doxorubicin in melanoma cancer cells by Mohammadian, Jamal, Mahmoudi, Shiva, Pourmohammad, Pirouz, Pirouzpanah, Mohammad, Salehnia, Fatemeh, Maroufi, Nazila Fathi, Samadi, Nasser, Sabzichi, Mehdi

“…Nowadays, nanoparticle-based combination therapy has been emerging as huge innovation in cancer treatment. Here, we studied the effect of Stattic (STAT3…”
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Downregulation of fatty acid oxidation by involvement of HIF-1α and PPARγ in human gastric adenocarcinoma and related clinical significance by Ezzeddini, Rana, Taghikhani, Mohammad, Salek Farrokhi, Amir, Somi, Mohammad Hossein, Samadi, Nasser, Esfahani, Ali, Rasaee, Mohammad Javad

“…Lipid metabolism rewiring in gastric adenocarcinoma (GA) pathogenesis is still not clearly elucidated. This study aimed to describe the role of lipid…”
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Comparison of genome‐wide analysis techniques to DNA methylation analysis in human cancer by Soozangar, Narges, Sadeghi, Mohammad R., Jeddi, Farhad, Somi, Mohammad H., Shirmohamadi, Masoud, Samadi, Nasser

“…DNA methylation was the first epigenetic modification to be detected in human cancers with specific relation to aberrant gene expression. Herein, DNA…”
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Sphingosine kinase-2 Inhibitor ABC294640 Enhances Doxorubicin-Induced Apoptosis of NSCLC Cells via Altering Survivin Expression by Leili, Hasanifard, Nasser, Samadi, Nadereh, Rashtchizadeh, Siavoush, Dastmalchi, Pouran, Karimi

“…There is an urgent need to improve efficacy of chemotherapeutics to overcome resistance in cancer treatment. Sphingosine kinase-2 (SphK2) a key regulator of…”
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Six Family of Homeobox Genes and Related Mechanisms in Tumorigenesis Protocols by Armat, Marzieh, Ramezani, Fatemeh, Molavi, Ommoleila, Sabzichi, Mehdi, Samadi, Nasser

“…In recent years, the homeobox gene superfamily has been introduced as a master regulator in downstream target genes related to cell development and…”
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NFκBP65 transcription factor modulates resistance to doxorubicin through ABC transporters in breast cancer by Velaei, Kobra, Samadi, Nasser, Soltani, Sina, Barazvan, Balal, Soleimani Rad, Jafar

“…Background Shedding light on chemoresistance biology of breast cancer could contribute to enhance the clinical outcome. Intrinsic or acquired resistance to…”
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Associations between Dietary Allium Vegetables and Risk of Breast Cancer: A Hospital-Based Matched Case-Control Study by Pourzand, Ali, Tajaddini, Aynaz, Pirouzpanah, Saeed, Asghari-Jafarabadi, Mohammad, Samadi, Nasser, Ostadrahimi, Ali-Reza, Sanaat, Zohreh

“…The protective effect of vegetables against carcinogenesis has been reported in experimental studies particularly focusing on the gut. Therefore, we conducted…”
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