Search Results - "Salzmann, Maren"
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Lipid catabolism inhibition sensitizes prostate cancer cells to antiandrogen blockade
Published in Oncotarget (22-08-2017)“…Prostate cancer (PCa) is the most common malignancy among Western men and the second leading-cause of cancer related deaths. For men who develop metastatic…”
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CPT1A Supports Castration-Resistant Prostate Cancer in Androgen-Deprived Conditions
Published in Cells (Basel, Switzerland) (20-09-2019)“…Prostate cancer (PCa) is the most common cancer in men, and the global burden of the disease is rising. The majority of PCa deaths are due to metastasis that…”
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Predictors and Prevalence of Paraganglioma Syndrome Associated With Mutations of the SDHC Gene
Published in JAMA : the journal of the American Medical Association (26-10-2005)“…CONTEXT Paraganglioma syndrome includes inherited head and neck paragangliomas (HNPs) and adrenal or extra-adrenal pheochromocytomas and are classified…”
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Preclinical evaluation of teleglenastat (CB-839) in prostate cancer
Published in Journal of clinical oncology (20-02-2023)“…378 Background: Glutaminase (GLS) levels are upregulated in prostate cancer [PMID: 28138303, 16897757]. The androgen receptor signaling pathway enhances the…”
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OR34-4 ATF3 Is A Converging Point For AR Signaling And Fatty Acid Oxidation In Prostate Cancer
Published in Journal of the Endocrine Society (30-04-2019)“…Prostate cancer (PCa) is the second most prevalent cancer and leading causes of death among men worldwide. Androgen deprivation is the first line of treatment…”
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Abstract A021: CPT1A-mediated fat oxidation and its role in the immune response to prostate cancer
Published in Cancer research (Chicago, Ill.) (15-08-2018)“…Abstract Background and Rationale: While impressive improvements in immunology have led to the identification of immune checkpoint proteins such as CTLA-4 and…”
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Abstract 1483: Lipid oxidation via CPT1 as a target for prostate cancer imaging and therapy
Published in Cancer research (Chicago, Ill.) (01-08-2015)“…Abstract Introduction: Prostate cancer (PCa) is the most common cancer in males and is currently treated medically with androgen deprivation therapy. However,…”
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Abstract 1055: CPT1A-mediated lipid catabolism modulates growth, AR expression and hypoxia survival of prostate cancer
Published in Cancer research (Chicago, Ill.) (15-07-2016)“…Abstract Background: Androgen deprivation results in hypoxia in prostate cancer (PCa) cells and subsequently enhances the transcriptional activity of AR…”
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