Fecal Microbiota and Diet of Children with Chronic Constipation

Many factors explain dysbiosis in chronic constipation (CC), such as a low-fiber diet. The objective of this study was to compare the fecal microbiota of constipated and nonconstipated children and their intake frequencies of food. Methods. This observational study included 79 children (M/F 43/36) a...

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Bibliographic Details
Published in:	International Journal of Pediatrics Vol. 2016; no. 2016; pp. 136 - 143
Main Authors:	Salviano, Taciana Lima, Beltrão, Monique Ferraz de Sá, Motta, Maria E. F. A., Moraes, Joyce Gomes de, Silva, Giselia Alves Pontes da
Format:	Journal Article
Language:	English
Published:	Cairo, Egypt Hindawi Limiteds 01-01-2016 Hindawi Publishing Corporation John Wiley & Sons, Inc Hindawi Limited
Subjects:	Analysis Care and treatment Constipation Diet Health aspects Microbiota (Symbiotic organisms) Prevention Risk factors Brazil
Online Access:	Get full text
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Summary:	Many factors explain dysbiosis in chronic constipation (CC), such as a low-fiber diet. The objective of this study was to compare the fecal microbiota of constipated and nonconstipated children and their intake frequencies of food. Methods. This observational study included 79 children (M/F 43/36) aged six to 36 months divided into two groups: cases (39 constipated children) and controls (40 nonconstipated children). We used a structured form to collect demographic variables, conducted anthropometric assessment, and collected food intake frequency data. The fecal microbiota of the stool samples was analyzed by real-time polymerase chain reaction (PCR) using the fluorophore SYBR® Green. Results. Constipated children had a smaller concentration of Lactobacillus per milligram of stool ( p = 0.015 ) than nonconstipated children, but the concentration of Bifidobacterium per milligram of stool ( p = 0.323 ) and the intake of fruits, vegetables ( p = 0.563 ), and junk food ( p = 0.093 ) of the two groups did not differ. Constipated children consumed more dairy products ( 0.45 ± 0.8 ; p > 0.001 ), were more frequently delivered via caesarean section (69.2%), were weaned earlier (median: 120; 60 Q 1 – 240 Q 3 ), and had a family history of constipation (71.8%). Conclusions. Children with CC have a smaller concentration of Lactobacillus in their stools and consume more dairy products.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 Academic Editor: Samuel Menahem
ISSN:	1687-9740 1687-9759
DOI:	10.1155/2016/6787269