Search Results - "Salvi, J."

Central gain control in tinnitus and hyperacusis by Auerbach, Benjamin D, Rodrigues, Paulo V, Salvi, Richard J

“…Sensorineural hearing loss induced by noise or ototoxic drug exposure reduces the neural activity transmitted from the cochlea to the central auditory system…”
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Underlying mechanisms of tinnitus: review and clinical implications by Henry, James A, Roberts, Larry E, Caspary, Donald M, Theodoroff, Sarah M, Salvi, Richard J

“…The study of tinnitus mechanisms has increased tenfold in the last decade. The common denominator for all of these studies is the goal of elucidating the…”
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Age-related hearing loss in C57BL/6J mice is mediated by Bak-dependent mitochondrial apoptosis by Someya, Shinichi, Xu, Jinze, Kondo, Kenji, Ding, Dalian, Salvi, Richard J, Yamasoba, Tatsuya, Rabinovitch, Peter S, Weindruch, Richard, Leeuwenburgh, Christiaan, Tanokura, Masaru, Prolla, Tomas A

“…Age-related hearing loss (AHL), known as presbycusis, is a universal feature of mammalian aging and is the most common sensory disorder in the elderly…”
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Cytotoxic effects of dimethyl sulphoxide (DMSO) on cochlear organotypic cultures by Qi, Weidong, Ding, Dalian, Salvi, Richard J.

“…The amphipathic molecule dimethyl sulphoxide (DMSO) is a solvent often used to dissolve compounds applied to the inner ear; however, little is known about its…”
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Neuroadaptations in the dorsal hippocampus underlie cocaine seeking during prolonged abstinence by Werner, Craig T., Mitra, Swarup, Auerbach, Benjamin D., Wang, Zi-Jun, Martin, Jennifer A., Stewart, Andrew F., Gobira, Pedro H., Iida, Madoka, An, Chunna, Cobb, Moriah M., Caccamise, Aaron, Salvi, Richard J., Neve, Rachael L., Gancarz, Amy M., Dietz, David M.

“…Relapse vulnerability in substance use disorder is attributed to persistent cue-induced drug seeking that intensifies (or “incubates”) during drug abstinence…”
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Noise trauma impairs neurogenesis in the rat hippocampus by Kraus, K.S, Mitra, S, Jimenez, Z, Hinduja, S, Ding, D, Jiang, H, Gray, L, Lobarinas, E, Sun, W, Salvi, R.J

“…Abstract The hippocampus, a major site of neurogenesis in the adult brain, plays an important role in memory. Based on earlier observations where exposure to…”
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Mutations in apoptosis-inducing factor cause X-linked recessive auditory neuropathy spectrum disorder by Zong, Liang, Guan, Jing, Ealy, Megan, Zhang, Qiujing, Wang, Dayong, Wang, Hongyang, Zhao, Yali, Shen, Zhirong, Campbell, Colleen A, Wang, Fengchao, Yang, Ju, Sun, Wei, Lan, Lan, Ding, Dalian, Xie, Linyi, Qi, Yue, Lou, Xin, Huang, Xusheng, Shi, Qiang, Chang, Suhua, Xiong, Wenping, Yin, Zifang, Yu, Ning, Zhao, Hui, Wang, Jun, Wang, Jing, Salvi, Richard J, Petit, Christine, Smith, Richard J H, Wang, Qiuju

“…Auditory neuropathy spectrum disorder (ANSD) is a form of hearing loss in which auditory signal transmission from the inner ear to the auditory nerve and brain…”
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Effects of Long-Term Exercise on Age-Related Hearing Loss in Mice by Han, Chul, Ding, Dalian, Lopez, Maria-Cecilia, Manohar, Senthilvelan, Zhang, Yanping, Kim, Mi-Jung, Park, Hyo-Jin, White, Karessa, Kim, Yong Hwan, Linser, Paul, Tanokura, Masaru, Leeuwenburgh, Christiaan, Baker, Henry V, Salvi, Richard J, Someya, Shinichi

“…Regular physical exercise reduces the risk for obesity, cardiovascular diseases, and disability and is associated with longer lifespan expectancy (Taylor et…”
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A new mouse model of Charcot-Marie-Tooth 2J neuropathy replicates human axonopathy and suggest alteration in axo-glia communication by Shackleford, Ghjuvan'Ghjacumu, Marziali, Leandro N, Sasaki, Yo, Claessens, Anke, Ferri, Cinzia, Weinstock, Nadav I, Rossor, Alexander M, Silvestri, Nicholas J, Wilson, Emma R, Hurley, Edward, Kidd, Grahame J, Manohar, Senthilvelan, Ding, Dalian, Salvi, Richard J, Feltri, M Laura, D'Antonio, Maurizio, Wrabetz, Lawrence

“…Myelin is essential for rapid nerve impulse propagation and axon protection. Accordingly, defects in myelination or myelin maintenance lead to secondary axonal…”
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Altered neuronal intrinsic properties and reduced synaptic transmission of the rat's medial geniculate body in salicylate-induced tinnitus by Su, Yan-Yan, Luo, Bin, Jin, Yan, Wu, Shu-Hui, Lobarinas, Edward, Salvi, Richard J, Chen, Lin

“…Sodium salicylate (NaSal), an aspirin metabolite, can cause tinnitus in animals and human subjects. To explore neural mechanisms underlying salicylate-induced…”
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Auditory plasticity and hyperactivity following cochlear damage by Salvi, Richard J, Wang, Jian, Ding, Dalian

“…This paper will review some of the functional changes that occur in the central auditory pathway after the cochlea is damaged by acoustic overstimulation or by…”
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Anti-muscarinic adjunct therapy accelerates functional human oligodendrocyte repair by Abiraman, Kavitha, Pol, Suyog U, O'Bara, Melanie A, Chen, Guang-Di, Khaku, Zainab M, Wang, Jing, Thorn, David, Vedia, Bansi H, Ekwegbalu, Ezinne C, Li, Jun-Xu, Salvi, Richard J, Sim, Fraser J

“…Therapeutic repair of myelin disorders may be limited by the relatively slow rate of human oligodendrocyte differentiation. To identify appropriate…”
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Salicylate-induced peripheral auditory changes and tonotopic reorganization of auditory cortex by Stolzberg, D, Chen, G.-D, Allman, B.L, Salvi, R.J

“…Abstract The neuronal mechanism underlying the phantom auditory perception of tinnitus remains elusive at present. For over 25 years, temporary tinnitus…”
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Salicylate increases the gain of the central auditory system by Sun, W, Lu, J, Stolzberg, D, Gray, L, Deng, A, Lobarinas, E, Salvi, R.J

“…Abstract High doses of salicylate, the anti-inflammatory component of aspirin, induce transient tinnitus and hearing loss. Systemic injection of 250 mg/kg of…”
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Mechanistic Analysis of Age-Related Clinical Manifestations in Down Syndrome by Chen, Xu-Qiao, Xing, Zhuo, Chen, Quang-Di, Salvi, Richard J, Zhang, Xuming, Tycko, Benjamin, Mobley, William C, Yu, Y Eugene

“…Down syndrome (DS) is the most common genetic cause of Alzheimer's disease (AD) due to trisomy for all or part of human chromosome 21 (Hsa21). It is also…”
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Cisplatin ototoxicity in rat cochlear organotypic cultures by Ding, Dalian, He, Jingchun, Allman, Brian L., Yu, Dongzhen, Jiang, Haiyan, Seigel, Gail M., Salvi, Richard J.

“…Ototoxicity is a dose-limiting side effect of chemotherapeutic treatment with cisplatin. In a series of experiments on neonatal rat cochlear organotypic…”
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Characteristics of somatic tinnitus patients with and without hyperacusis by Ralli, Massimo, Salvi, Richard J, Greco, Antonio, Turchetta, Rosaria, De Virgilio, Armando, Altissimi, Giancarlo, Attanasio, Giuseppe, Cianfrone, Giancarlo, de Vincentiis, Marco

“…Determine if somatic tinnitus patients with hyperacusis have different characteristics from those without hyperacusis. 172 somatic tinnitus patients with (n =…”
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Salicylate toxicity model of tinnitus by Stolzberg, Daniel, Salvi, Richard J, Allman, Brian L

“…Salicylate, the active component of the common drug aspirin, has mild analgesic, antipyretic, and anti-inflammatory effects at moderate doses. At higher doses,…”
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Effects of acoustic trauma on the auditory system of the rat: The role of microglia by Baizer, J.S, Wong, K.M, Manohar, S, Hayes, S.H, Ding, D, Dingman, R, Salvi, R.J

“…Highlights • We studied auditory nerve degeneration and microglia activation after bilateral noise exposure destroying hair cells. • At survival times of 30…”
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Intracortical circuits amplify sound-evoked activity in primary auditory cortex following systemic injection of salicylate in the rat by Stolzberg, Daniel, Chrostowski, Michael, Salvi, Richard J, Allman, Brian L

“…A high dose of sodium salicylate temporarily induces tinnitus, mild hearing loss, and possibly hyperacusis in humans and other animals. Salicylate has…”
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