Search Results - "Salvarani, Nicolo"

Histone Methyltransferase G9a is Required for Cardiomyocyte Homeostasis and Hypertrophy by Papait, Roberto, Serio, Simone, Pagiatakis, Christina, Rusconi, Francesca, Carullo, Pierluigi, Mazzola, Marta, Salvarani, Nicolò, Miragoli, Michele, Condorelli, Gianluigi

“…BACKGROUND—Correct gene expression programming of the cardiomyocyte underlies the normal functioning of the heart. Alterations to this can lead to the loss of…”
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Cardiac Aging Is Promoted by Pseudohypoxia Increasing p300-Induced Glycolysis by Serio, Simone, Pagiatakis, Christina, Musolino, Elettra, Felicetta, Arianna, Carullo, Pierluigi, Laura Frances, Javier, Papa, Laura, Rozzi, Giacomo, Salvarani, Nicolò, Miragoli, Michele, Gornati, Rosalba, Bernardini, Giovanni, Condorelli, Gianluigi, Papait, Roberto

“…Heart failure is typical in the elderly. Metabolic remodeling of cardiomyocytes underlies inexorable deterioration of cardiac function with aging: glycolysis…”
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Aggravation of cardiac myofibroblast arrhythmogeneicity by mechanical stress by Grand, Teddy, Salvarani, Nicolò, Jousset, Florian, Rohr, Stephan

“…Myofibroblasts (MFBs) as appearing in the myocardium during fibrotic remodelling induce slow conduction following heterocellular gap junctional coupling with…”
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Abolishing Myofibroblast Arrhythmogeneicity by Pharmacological Ablation of α-Smooth Muscle Actin Containing Stress Fibers by Rosker, Christian, Salvarani, Nicolò, Schmutz, Stephan, Grand, Teddy, Rohr, Stephan

“…RATIONALE:Myofibroblasts typically appear in the myocardium after insults to the heart like mechanical overload and infarction. Apart from contributing to…”
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Electroactive polyurethane/siloxane derived from castor oil as a versatile cardiac patch, part I: Synthesis, characterization, and myoblast proliferation and differentiation by Baheiraei, Nafiseh, Gharibi, Reza, Yeganeh, Hamid, Miragoli, Michele, Salvarani, Nicolò, Di Pasquale, Elisa, Condorelli, Gianluigi

“…Tissue‐engineered cardiac patch aims at regenerating an infarcted heart by improving cardiac function and providing mechanical support to the diseased…”
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Electroactive polyurethane/siloxane derived from castor oil as a versatile cardiac patch, part II: HL-1 cytocompatibility and electrical characterizations by Baheiraei, Nafiseh, Gharibi, Reza, Yeganeh, Hamid, Miragoli, Michele, Salvarani, Nicolò, Di Pasquale, Elisa, Condorelli, Gianluigi

“…In first part of this experiment, biocompatibility of the newly developed electroactive polyurethane/siloxane films containing aniline tetramer moieties was…”
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A protective antiarrhythmic role of ursodeoxycholic acid in an in vitro rat model of the cholestatic fetal heart by Miragoli, Michele, Kadir, Siti H. Sheikh Abdul, Sheppard, Mary N., Salvarani, Nicoló, Virta, Matilda, Wells, Sarah, Lab, Max J., Nikolaev, Viacheslav O., Moshkov, Alexey, Hague, William M., Rohr, Stephan, Williamson, Catherine, Gorelik, Julia

“…Intrahepatic cholestasis of pregnancy may be complicated by fetal arrhythmia, fetal hypoxia, preterm labor, and, in severe cases, intrauterine death. The…”
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Electroactive polyurethane/siloxane derived from castor oil as a versatile cardiac patch, part I: Synthesis, characterization,and myoblast proliferation and differentiation by Baheiraei, Nafiseh, Gharibi, Reza, Yeganeh, Hamid, Miragoli, Michele, Salvarani, Nicolò, Di Pasquale, Elisa, Condorelli, Gianluigi

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Myofibroblasts Induce Ectopic Activity in Cardiac Tissue by Miragoli, Michele, Salvarani, Nicolò, Rohr, Stephan

“…Focal ectopic activity in cardiac tissue is a key factor in the initiation and perpetuation of tachyarrhythmias. Because myofibroblasts as present in fibrotic…”
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miR-128-3p Is a Novel Regulator of Vascular Smooth Muscle Cell Phenotypic Switch and Vascular Diseases by Farina, Floriana Maria, Hall, Ignacio Fernando, Serio, Simone, Zani, Stefania, Climent, Montserrat, Salvarani, Nicolò, Carullo, Pierluigi, Civilini, Efrem, Condorelli, Gianluigi, Elia, Leonardo, Quintavalle, Manuela

“…MicroRNAs (miRNAs, miRs) are small noncoding RNAs that modulate gene expression by negatively regulating translation of target genes. Although the role of…”
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The K219T-Lamin mutation induces conduction defects through epigenetic inhibition of SCN5A in human cardiac laminopathy by Salvarani, Nicolò, Crasto, Silvia, Miragoli, Michele, Bertero, Alessandro, Paulis, Marianna, Kunderfranco, Paolo, Serio, Simone, Forni, Alberto, Lucarelli, Carla, Dal Ferro, Matteo, Larcher, Veronica, Sinagra, Gianfranco, Vezzoni, Paolo, Murry, Charles E., Faggian, Giuseppe, Condorelli, Gianluigi, Di Pasquale, Elisa

“…Mutations in LMNA , which encodes the nuclear proteins Lamin A/C, can cause cardiomyopathy and conduction disorders. Here, we employ induced pluripotent stem…”
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Temporal variability of repolarization in rat ventricular myocytes paced with time-varying frequencies by Zaniboni, Massimiliano, Cacciani, Francesca, Salvarani, Nicolò

“…Adaptation of action potential duration (APD) to pacing cycle length (CL) has been previously characterized in isolated cardiomyocytes for sudden changes in…”
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Synthetic recovery of impulse propagation in myocardial infarction via silicon carbide semiconductive nanowires by Lagonegro, Paola, Rossi, Stefano, Salvarani, Nicolò, Lo Muzio, Francesco Paolo, Rozzi, Giacomo, Modica, Jessica, Bigi, Franca, Quaretti, Martina, Salviati, Giancarlo, Pinelli, Silvana, Alinovi, Rossella, Catalucci, Daniele, D’Autilia, Francesca, Gazza, Ferdinando, Condorelli, Gianluigi, Rossi, Francesca, Miragoli, Michele

“…Myocardial infarction causes 7.3 million deaths worldwide, mostly for fibrillation that electrically originates from the damaged areas of the left ventricle…”
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Bioinspired negatively charged calcium phosphate nanocarriers for cardiac delivery of MicroRNAs by Di Mauro, Vittoria, Iafisco, Michele, Salvarani, Nicolò, Vacchiano, Marco, Carullo, Pierluigi, Ramírez-Rodríguez, Gloria Belén, Patrício, Tatiana, Tampieri, Anna, Miragoli, Michele, Catalucci, Daniele

“…To develop biocompatible and bioresorbable negatively charged calcium phosphate nanoparticles (CaP-NPs) as an innovative therapeutic system for the delivery of…”
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Unlocking cardiac motion: assessing software and machine learning for single-cell and cardioid kinematic insights by Burattini, Margherita, Lo Muzio, Francesco Paolo, Hu, Mirko, Bonalumi, Flavia, Rossi, Stefano, Pagiatakis, Christina, Salvarani, Nicolò, Fassina, Lorenzo, Luciani, Giovanni Battista, Miragoli, Michele

“…The heart coordinates its functional parameters for optimal beat-to-beat mechanical activity. Reliable detection and quantification of these parameters still…”
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Functional Characterisation of the Rare SCN5A p.E1225K Variant, Segregating in a Brugada Syndrome Familial Case, in Human Cardiomyocytes from Pluripotent Stem Cells by Salvarani, Nicolò, Peretto, Giovanni, Silvia, Crasto, Villatore, Andrea, Thairi, Cecilia, Santoni, Anna, Galli, Camilla, Carrera, Paola, Sala, Simone, Benedetti, Sara, Di Pasquale, Elisa, Di Resta, Chiara

“…Brugada syndrome (BrS) is an inherited autosomal dominant cardiac channelopathy. Pathogenic rare mutations in the gene, encoding the alpha-subunit of the…”
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Peptide-Based Targeting of the L-Type Calcium Channel Corrects the Loss-of-Function Phenotype of Two Novel Mutations of the CACNA1 Gene Associated With Brugada Syndrome by Di Mauro, Vittoria, Ceriotti, Paola, Lodola, Francesco, Salvarani, Nicolò, Modica, Jessica, Bang, Marie-Louise, Mazzanti, Andrea, Napolitano, Carlo, Priori, Silvia G, Catalucci, Daniele

“…Brugada syndrome (BrS) is an inherited arrhythmogenic disease that may lead to sudden cardiac death in young adults with structurally normal hearts. No…”
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Abstract P1102: Organic Semiconductor Photomodulation Enhances Maturation Of Pluripotent Stem Cell-derived Cardiomyocytes by Galli, Camilla, Salvarani, Nicolo, Ronchi, Carlotta, Tullii, Gabriele, Marzuoli, Camilla, Malferrari, Marco, Rapino, Stefania, Antognazza, Maria Rosa, Di Pasquale, Elisa

“…Abstract only Cardiomyocytes differentiated from pluripotent stem cells (PSC-CMs) hold a great potential for the study and the cure of cardiovascular disease;…”
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TGF-β1 (Transforming Growth Factor-β1) Plays a Pivotal Role in Cardiac Myofibroblast Arrhythmogenicity by Salvarani, Nicolò, Maguy, Ange, De Simone, Stefano A, Miragoli, Michele, Jousset, Florian, Rohr, Stephan

“…BACKGROUNDTGF-β1 (transforming growth factor-β1) importantly contributes to cardiac fibrosis by controlling differentiation, migration, and collagen secretion…”
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Single-Cell RNA Sequencing Reveals Metabolic Stress-Dependent Activation of Cardiac Macrophages in a Model of Dyslipidemia-Induced Diastolic Dysfunction by Panico, Cristina, Felicetta, Arianna, Kunderfranco, Paolo, Cremonesi, Marco, Salvarani, Nicolò, Carullo, Pierluigi, Colombo, Federico, Idini, Alessandra, Passaretti, Mauro, Doro, Riccardo, Rubino, Marcello, Villaschi, Alessandro, Da Rin, Giorgio, Peano, Clelia, Kallikourdis, Marinos, Greco, Carolina M., Condorelli, Gianluigi

“…Metabolic distress is often associated with heart failure with preserved ejection fraction (HFpEF) and represents a therapeutic challenge. Metabolism-induced…”
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