Search Results - "Salvador‐Pascual, Andrea"

Overexpression of CYB5R3 and NQO1, two NAD+‐producing enzymes, mimics aspects of caloric restriction by Diaz‐Ruiz, Alberto, Lanasa, Michael, Garcia, Joseph, Mora, Hector, Fan, Frances, Martin‐Montalvo, Alejandro, Di Francesco, Andrea, Calvo‐Rubio, Miguel, Salvador‐Pascual, Andrea, Aon, Miguel A., Fishbein, Kenneth W., Pearson, Kevin J., Villalba, Jose Manuel, Navas, Placido, Bernier, Michel, de Cabo, Rafael

“…Summary Calorie restriction (CR) is one of the most robust means to improve health and survival in model organisms. CR imposes a metabolic program that leads…”
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Glucose 6‐P dehydrogenase delays the onset of frailty by protecting against muscle damage by Arc‐Chagnaud, Coralie, Salvador‐Pascual, Andrea, Garcia‐Dominguez, Esther, Olaso‐Gonzalez, Gloria, Correas, Angela G., Serna, Eva, Brioche, Thomas, Chopard, Angele, Fernandez‐Marcos, Pablo J., Serrano, Manuel, Serrano, Antonio L., Muñoz‐Cánoves, Pura, Sebastiá, Vicente, Viña, Jose, Gomez‐Cabrera, Mari Carmen

“…Background Frailty is a major age‐associated syndrome leading to disability. Oxidative damage plays a significant role in the promotion of frailty. The…”
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Redox modulation of mitochondriogenesis in exercise. Does antioxidant supplementation blunt the benefits of exercise training? by Gomez-Cabrera, Mari Carmen, Salvador-Pascual, Andrea, Cabo, Helena, Ferrando, Beatriz, Viña, Jose

“…Physical exercise increases the cellular production of reactive oxygen species (ROS) in muscle, liver, and other organs. This is unlikely due to increased…”
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G6PD protects from oxidative damage and improves healthspan in mice by Nóbrega-Pereira, Sandrina, Fernandez-Marcos, Pablo J., Brioche, Thomas, Gomez-Cabrera, Mari Carmen, Salvador-Pascual, Andrea, Flores, Juana M., Viña, Jose, Serrano, Manuel

“…Reactive oxygen species (ROS) are constantly generated by cells and ROS-derived damage contributes to ageing. Protection against oxidative damage largely…”
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Physical exercise in the prevention and treatment of Alzheimer's disease by De la Rosa, Adrian, Olaso-Gonzalez, Gloria, Arc-Chagnaud, Coralie, Millan, Fernando, Salvador-Pascual, Andrea, García-Lucerga, Consolacion, Blasco-Lafarga, Cristina, Garcia-Dominguez, Esther, Carretero, Aitor, Correas, Angela G., Viña, Jose, Gomez-Cabrera, Mari Carmen

“…•Low levels of physical activity are a risk factor associated with Alzheimer's disease.•Older adults who exercise are more likely to maintain…”
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A Multicomponent Exercise Intervention that Reverses Frailty and Improves Cognition, Emotion, and Social Networking in the Community-Dwelling Frail Elderly: A Randomized Clinical Trial by Tarazona-Santabalbina, Francisco José, MD, PhD, Gómez-Cabrera, Mari Carmen, PhD, Pérez-Ros, Pilar, PhD, Martínez-Arnau, Francisco Miguel, PhD, Cabo, Helena, PhD, Tsaparas, Konstantina, PhD, Salvador-Pascual, Andrea, PhD, Rodriguez-Mañas, Leocadio, MD, PhD, Viña, José, MD, PhD

“…Abstract Background Frailty can be an important clinical target to reduce rates of disability. Objective To ascertain if a supervised-facility multicomponent…”
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Exercise: the lifelong supplement for healthy ageing and slowing down the onset of frailty by Viña, Jose, Rodriguez‐Mañas, Leocadio, Salvador‐Pascual, Andrea, Tarazona‐Santabalbina, Francisco José, Gomez‐Cabrera, Mari Carmen

“…The beneficial effects of exercise have been well recognized for over half a century. Dr Jeremy Morris's pioneering studies in the fifties showed a striking…”
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Peroxiredoxin 6 suppresses erastin‐induced ferroptosis in lung endothelial cells by Vazquez‐Medina, Jose P., Torres‐Velarde, Julia M., Allen, Kaitlin N., Salvador‐Pascual, Andrea, Ensminger, David C.

“…Ferroptosis is a newly described form of regulated cell death driven by an iron‐dependent accumulation of phospholipid hydroperoxides. Glutathione peroxidase 4…”
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Exercise training as a drug to treat age associated frailty by Viña, Jose, Salvador-Pascual, Andrea, Tarazona-Santabalbina, Francisco Jose, Rodriguez-Mañas, Leocadio, Gomez-Cabrera, Mari Carmen

“…Exercise causes an increase in the production of free radicals [1]. As a result of a hormetic mechanism antioxidant enzymes are synthesised and the cells are…”
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Allopurinol partially prevents disuse muscle atrophy in mice and humans by Ferrando, Beatriz, Gomez-Cabrera, Mari Carmen, Salvador-Pascual, Andrea, Puchades, Carlos, Derbré, Frederic, Gratas-Delamarche, Arlette, Laparre, Ludovic, Olaso-Gonzalez, Gloria, Cerda, Miguel, Viosca, Enrique, Alabajos, Ana, Sebastiá, Vicente, Alberich-Bayarri, Angel, García-Castro, Fabio, Viña, Jose

“…Disuse muscle wasting will likely affect everyone in his or her lifetime in response to pathologies such as joint immobilization, inactivity or bed rest. There…”
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Overexpression of G6PD as a model of robustness by Coralie, Arc-Chagnaud, Andrea, Salvador-Pascual, Aitor, Carretero, Thomas, Brioche, Angèle, Chopard, Fernandez-Marcos, PJ, Serrano, M, Carmen, Gomez-Cabrera Mari, Jose, Viña

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Disinfection by-products effect on swimmers oxidative stress and respiratory damage by Llana-Belloch, Salvador, Priego Quesada, Jose Ignacio, Pérez-Soriano, Pedro, Lucas-Cuevas, Ángel G., Salvador-Pascual, Andrea, Olaso-González, Gloria, Moliner-Martinez, Yolanda, Verdú-Andres, Jorge, Campins-Falco, Pilar, Gómez-Cabrera, M. Carmen

“…Disinfection by-products (DBPs) are generated through the reaction of chlorine with organic and inorganic matter in indoor swimming pools. Different DBPs are…”
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Peroxiredoxin 6 suppresses ferroptosis in lung endothelial cells by Torres-Velarde, Julia Maria, Allen, Kaitlin, Salvador-Pascual, Andrea, Ensminger, David, Vazquez-Medina, Jose Pablo

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Fasting ameliorates oxidative stress: A review of physiological strategies across life history events in wild vertebrates by Ensminger, David C., Salvador-Pascual, Andrea, Arango, B. Gabriela, Allen, Kaitlin N., Vázquez-Medina, José Pablo

“…Fasting is a component of many species' life history due to environmental factors or behavioral patterns that limit access to food. Despite metabolic and…”
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A New Frailty Score for Experimental Animals Based on the Clinical Phenotype: Inactivity as a Model of Frailty by Gomez-Cabrera, Mari Carmen, Garcia-Valles, Rebeca, Rodriguez-Mañas, Leocadio, Garcia-Garcia, Francisco Jose, Olaso-Gonzalez, Gloria, Salvador-Pascual, Andrea, Tarazona-Santabalbina, Francisco Jose, Viña, Jose

“…The development of animal models to study human frailty is important to test interventions to be translated to the clinical practice. The aim of this work was…”
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Peroxiredoxin 6 suppresses ferroptosis in lung endothelial cells by Torres-Velarde, Julia María, Allen, Kaitlin N., Salvador-Pascual, Andrea, Leija, Roberto G., Luong, Diamond, Moreno-Santillán, Diana Daniela, Ensminger, David C., Vázquez-Medina, José Pablo

“…Peroxiredoxin 6 (Prdx6) repairs peroxidized membranes by reducing oxidized phospholipids, and by replacing oxidized sn-2 fatty acyl groups through…”
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PL-08 - Modulation of ROS levels as a strategy to improve healthy aging by Carmen Gomez-Cabrera, Mari, Salvador-Pascual, Andrea, Viña, Jose

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Modulation of ROS levels as a strategy to improve healthy aging by Carmen Gomez-Cabrera, Mari, Salvador-Pascual, Andrea, Viña, Jose

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Biology of frailty: Modulation of ageing genes and its importance to prevent age-associated loss of function by Viña, Jose, Tarazona-Santabalbina, Francisco Jose, Pérez-Ros, Pilar, Martínez-Arnau, Francisco Miguel, Borras, Consuelo, Olaso-Gonzalez, Gloria, Salvador-Pascual, Andrea, Gomez-Cabrera, Mari Carmen

“…Frailty is associated with loss of functional reserve as well as with the prediction of adverse events in the old population. The traditional criteria of…”
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Early reductive stress followed by a late onset oxidative stress in acute myocardial infarction by Carretero, Aitor, Rios-Navarro, Cesar, Diaz, Ana, Salvador-Pascual, Andrea, Millan, Fernando, Garcia-Dominguez, Esther, Garcia-Correas, Angela, Garcia-Dominguez, Cristina, De la Rosa, Adrian, Arc-Chagnaud, Coralie, Olaso-Gonzalez, Gloria, Bodi, Vicent, Gomez-Cabrera, Mari Carmen, Viña, José

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