Search Results - "Salvà, Francesc"

Ongoing and evolving clinical trials enhancing future colorectal cancer treatment strategies by Ros, Javier, Saoudi, Nadia, Salvà, Francesc, Baraibar, Iosune, Alonso, Guzman, Tabernero, Josep, Elez, Elena

“…Molecular profiling has led to significantly longer survival in metastatic colorectal cancer (CRC) patients. Clinical guidelines recommend testing for and…”
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Combined Treatment with Immunotherapy-Based Strategies for MSS Metastatic Colorectal Cancer by Baraibar, Iosune, Mirallas, Oriol, Saoudi, Nadia, Ros, Javier, Salvà, Francesc, Tabernero, Josep, Élez, Elena

“…In recent years, deepening knowledge of the complex interactions between the immune system and cancer cells has led to the advent of effective immunotherapies…”
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Immunotherapy for Colorectal Cancer with High Microsatellite Instability: The Ongoing Search for Biomarkers by Ros, Javier, Baraibar, Iosune, Saoudi, Nadia, Rodriguez, Marta, Salvà, Francesc, Tabernero, Josep, Élez, Elena

“…Microsatellite instability (MSI) is a biological condition associated with inflamed tumors, high tumor mutational burden (TMB), and responses to immune…”
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Determinants of Metastatic Colorectal Cancer With Permanent Liver- Limited Disease by Salvà, Francesc, Saoudi, Nadia, Rodríguez, Marta, Baraibar, Iosune, Ros, Javier, García, Ariadna, Tabernero, Josep, Elez, Elena

“…•Around 20%-25% of patients with colorectal cancer (CRC) will develop exclusively hepatic metastatic disease throughout their disease history.•Patients with…”
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A Comprehensive Biomarker Analysis of Microsatellite Unstable/Mismatch Repair Deficient Colorectal Cancer Cohort Treated with Immunotherapy by Élez, Elena, Mulet-Margalef, Núria, Sanso, Miriam, Ruiz-Pace, Fiorella, Mancuso, Francesco M, Comas, Raquel, Ros, Javier, Argilés, Guillem, Martini, Giulia, Sanz-Garcia, Enrique, Baraibar, Iosune, Salvà, Francesc, Noguerido, Alba, Cuadra-Urteaga, Jose Luis, Fasani, Roberta, Garcia, Ariadna, Jimenez, Jose, Aguilar, Susana, Landolfi, Stefania, Hernández-Losa, Javier, Braña, Irene, Nuciforo, Paolo, Dienstmann, Rodrigo, Tabernero, Josep, Salazar, Ramon, Vivancos, Ana

“…The search for immunotherapy biomarkers in Microsatellite Instability High/Deficient Mismatch Repair system (MSI-H/dMMR) metastatic colorectal cancer (mCRC) is…”
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EGFR Amplification in Metastatic Colorectal Cancer by Randon, Giovanni, Yaeger, Rona, Hechtman, Jaclyn F, Manca, Paolo, Fucà, Giovanni, Walch, Henry, Lee, Jeeyun, Élez, Elena, Seligmann, Jenny, Mussolin, Benedetta, Pagani, Filippo, Germani, Marco Maria, Ambrosini, Margherita, Rossini, Daniele, Ratti, Margherita, Salvà, Francesc, Richman, Susan D, Wood, Henry, Nanjangud, Gouri, Gloghini, Annunziata, Milione, Massimo, Bardelli, Alberto, de Braud, Filippo, Morano, Federica, Cremolini, Chiara, Pietrantonio, Filippo

“…EGFR amplification occurs in about 1% of metastatic colorectal cancers (mCRCs) but is not routinely tested as a prognostic or predictive biomarker for patients…”
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Dynamic nature of BRAF or KRAS p.G12C mutations in second-line therapy for advanced colorectal cancer patients: do early and late effects exist? by Contreras-Toledo, Débora, Jiménez-Fonseca, Paula, López, Carlos López, Montes, Ana Fernández, López Muñoz, Ana María, Vázquez Rivera, Francisca, Alonso, Vicente, Alcaide, Julia, Salvà, Francesc, Covela Rúa, Marta, Guillot, Mónica, Martín Carnicero, Alfonso, Jimeno Mate, Raquel, Cameselle García, Soledad, Asensio Martínez, Elena, González Astorga, Beatriz, Fernandez-Diaz, Amaya B., González Villaroel, Paula, Virgili Manrique, Anna C., Melián Sosa, Marcos, Alonso, Beatriz, Cousillas Castiñeiras, Antia, Castañón López, Carmen, Aparicio, Jorge, Carmona-Bayonas, Alberto

“…Introduction The mitogen-activated protein kinase (MAPK) signalling network aberrations in metastatic colorectal cancer (mCRC) generate intrinsic dynamic…”
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Impact of the COVID-19 pandemic in the early-onset colorectal cancer by Baraibar, Iosune, García, Ariadna, Salvà, Francesc, Ros, Javier, Saoudi, Nadia, Comas, Raquel, Castillo, Gloria, Sanchis, Mireia, García-Álvarez, Alejandro, Hernando, Jorge, Capdevila, Jaume, Castells, Marta R, Martí, Marc, Landolfi, Stefania, Espín, Eloy, Navalpotro, Begoña, Guevara, Jorge, Dopazo, Cristina, Nuciforo, Paolo, Vivancos, Ana, Tabernero, Josep, Élez, Elena

“…•Patients with EOCRC faced multiple challenges during the COVID19 pandemic and in some institutions it could jeopardize cancer diagnosis and care delivery.•We…”
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Cost-minimisation analysis of rectal cancer neoadjuvant chemoradiotherapy based on fluoropyrimidines (capecitabine versus 5-fluorouracil) by Marin, Sergio, Pérez-Cordón, Laia, Salvà, Francesc, Camps, Marcel·la, Campins, Lluís, Lianes, Pilar

“…ObjectivesThe current standard treatment for patients with rectal cancer stage II–III is neoadjuvant chemoradiotherapy followed by surgery. Neoadjuvant…”
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Neoadjuvant chemotherapy in early-stage non-small cell lung cancer by Salvà, Francesc, Felip, Enriqueta

“…Surgical resection followed by adjuvant chemotherapy is the standard of care for completely resected stages II and III non-small cell lung cancer (NSCLC)…”
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The role of pro‐, pre‐ and symbiotics in cancer: A systematic review by Miarons, Marta, Roca, Maria, Salvà, Francesc

“…What is known and objective Cancer is one of the most important causes of morbidity and mortality worldwide. Pro‐, pre‐ and symbiotics can modulate host…”
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BRAF, MEK and EGFR inhibition as treatment strategies in BRAF V600E metastatic colorectal cancer by Ros, Javier, Baraibar, Iosune, Sardo, Emilia, Mulet, Nuria, Salvà, Francesc, Argilés, Guillem, Martini, Giulia, Ciardiello, Davide, Cuadra, José Luis, Tabernero, Josep, Élez, Elena

“…Introduction: BRAF driver mutations are found in up to 15% of patients with colorectal cancer (CRC) and lead to constitutive activation of BRAF kinase and…”
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Advances in immune checkpoint inhibitor combination strategies for microsatellite stable colorectal cancer by Ros, Javier, Balconi, Francesca, Baraibar, Iosune, Saoudi Gonzalez, Nadia, Salva, Francesc, Tabernero, Josep, Elez, Elena

“…Immune checkpoint inhibitors have reshaped the prognostic of several tumor types, including metastatic colorectal tumors with microsatellite instability (MSI)…”
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Epidermal growth factor receptor antagonists in colorectal cancer: emerging strategies for precision therapy by González, Nadia Saoudi, Marchese, Paola Valeria, Baraibar, Iosune, Ros, Javier, Salvà, Francesc, Rodríguez, Marta, Salvà, Clara, Vaghi, Caterina, Alcaraz, Adriana, García, Ariadna, Tabernero, Josep, Élez, Elena

“…The global prevalence of colorectal cancer highlights the need to enhance treatment strategies for improved patient outcomes. The pivotal role of epidermal…”
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The Evolving Role of Consensus Molecular Subtypes: a Step Beyond Inpatient Selection for Treatment of Colorectal Cancer by Ros, Javier, Baraibar, Iosune, Martini, Giulia, Salvà, Francesc, Saoudi, Nadia, Cuadra‑Urteaga, José Luis, Dienstmann, Rodrigo, Tabernero, Josep, Élez, Elena

“…Opinion statement The heterogenous nature of colorectal cancer (CRC) renders it a major clinical challenge. Increasing genomic understanding of CRC has…”
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The impact of clinical and translational research on the quality of life during the metastatic colorectal cancer patient journey by Rodriguez Castells, Marta, Baraibar, Iosune, Ros, Javier, Saoudi, Nadia, Salvà, Francesc, García, Ariadna, Alcaraz, Adriana, Tabernero, Josep, Élez, Elena

“…The journey of metastatic colorectal cancer patients is complex and challenging, requiring coordination and collaboration between multiple healthcare…”
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Molecular subtypes and the evolution of treatment management in metastatic colorectal cancer by Martini, Giulia, Dienstmann, Rodrigo, Ros, Javier, Baraibar, Iosune, Cuadra-Urteaga, Jose Luis, Salva, Francesc, Ciardiello, Davide, Mulet, Nuria, Argiles, Guillem, Tabernero, Josep, Elez, Elena

“…Colorectal cancer (CRC) is a heterogeneous disease representing a therapeutic challenge, which is further complicated by the common occurrence of several…”
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Targeting KRAS G12C Mutation in Colorectal Cancer, A Review: New Arrows in the Quiver by Ros, Javier, Vaghi, Caterina, Baraibar, Iosune, Saoudi González, Nadia, Rodríguez-Castells, Marta, García, Ariadna, Alcaraz, Adriana, Salva, Francesc, Tabernero, Josep, Elez, Elena

“…Kirsten rat sarcoma virus oncogene homolog ( ) is the most frequently mutated oncogene in human cancer. In colorectal cancer (CRC), mutations are present in…”
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Unravelling the Complexity of Colorectal Cancer: Heterogeneity, Clonal Evolution, and Clinical Implications by Saoudi González, Nadia, Salvà, Francesc, Ros, Javier, Baraibar, Iosune, Rodríguez-Castells, Marta, García, Ariadna, Alcaráz, Adriana, Vega, Sharela, Bueno, Sergio, Tabernero, Josep, Elez, Elena

“…Colorectal cancer (CRC) is a global health concern and a leading cause of death worldwide. The disease’s course and response to treatment are significantly…”
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Current and Emerging Treatment Paradigms in Colorectal Cancer: Integrating Hallmarks of Cancer by Salva de Torres, Clara, Baraibar, Iosune, Saoudi González, Nadia, Ros, Javier, Salva, Francesc, Rodríguez-Castells, Marta, Alcaraz, Adriana, García, Ariadna, Tabernero, Josep, Élez, Elena

“…The treatment of unresectable metastatic colorectal cancer has evolved over the last two decades, as knowledge of cancer biology has broadened and new targets…”
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