Search Results - "Saluja, K."

Protective effect of rutin on humoral and cell mediated immunity in rat model by Ganeshpurkar, Aditya, Saluja, Ajay K.

“…Diet and dietary intake can persuade the development, safeguard and proper functioning of immune system. Ruin, an important bioflavonoid, is abundantly found…”
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Vascular Disease Patient Information Page: Addressing disparities in peripheral artery disease-related amputation by Alabi, Olamide, Mahabamunuge, Saluja K

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Impaired Synthesis of Stromal Components in Response to Minnelide Improves Vascular Function, Drug Delivery, and Survival in Pancreatic Cancer by Banerjee, Sulagna, Modi, Shrey, McGinn, Olivia, Zhao, Xianda, Dudeja, Vikas, Ramakrishnan, Sundaram, Saluja, Ashok K

“…Pancreatic cancer stromal microenvironment is considered to be the major reason for failure of conventional and targeted therapy for this disease. The…”
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Relevance of Animal Models of Pancreatic Cancer and Pancreatitis to Human Disease by Saluja, Ashok K, Dudeja, Vikas

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Release of Cathepsin B in Cytosol Causes Cell Death in Acute Pancreatitis by Talukdar, Rupjyoti, Sareen, Archana, Zhu, Hongyan, Yuan, Zuobiao, Dixit, Ajay, Cheema, Hassam, George, John, Barlass, Usman, Sah, Raghuwansh, Garg, Sushil K, Banerjee, Sulagna, Garg, Pramod, Dudeja, Vikas, Dawra, Rajinder, Saluja, Ashok K

“…Background & Aims Experimental studies in acute pancreatitis (AP) suggest a strong association of acinar cell injury with cathepsin B–dependent intracellular…”
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Pathogenic mechanisms of acute pancreatitis by Sah, Raghuwansh P, Garg, Pramod, Saluja, Ashok K

“…PURPOSE OF REVIEWIn this article, recent advances in the pathogenesis of acute pancreatitis have been reviewed. RECENT FINDINGSPathologic intra-acinar…”
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A preclinical evaluation of Minnelide as a therapeutic agent against pancreatic cancer by Chugh, Rohit, Sangwan, Veena, Patil, Satish P, Dudeja, Vikas, Dawra, Rajinder K, Banerjee, Sulagna, Schumacher, Robert J, Blazar, Bruce R, Georg, Gunda I, Vickers, Selwyn M, Saluja, Ashok K

“…Pancreatic cancer is one of the most lethal human malignancies with an all-stage 5-year survival frequency of <5%, which highlights the urgent need for more…”
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CD133 initiates tumors, induces epithelial-mesenchymal transition and increases metastasis in pancreatic cancer by Nomura, Alice, Banerjee, Sulagna, Chugh, Rohit, Dudeja, Vikas, Yamamoto, Masato, Vickers, Selwyn M, Saluja, Ashok K

“…CD133 has been implicated as a cancer stem cell (CSC) surface marker in several malignancies including pancreatic cancer. However, the functional role of this…”
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Triptolide induces the expression of miR-142-3p: a negative regulator of heat shock protein 70 and pancreatic cancer cell proliferation by MacKenzie, Tiffany N, Mujumdar, Nameeta, Banerjee, Sulagna, Sangwan, Veena, Sarver, Aaron, Vickers, Selwyn, Subramanian, Subbaya, Saluja, Ashok K

“…Pancreatic ductal adenocarcinoma (PDAC), one of the deadliest malignancies, is resistant to current chemotherapies. We previously showed that triptolide…”
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Triptolide induces pancreatic cancer cell death via inhibition of heat shock protein 70 by PHILLIPS, Phoebe A, DUDEJA, Vikas, MCCARROLL, Joshua A, BORJA-CACHO, Daniel, DAWRA, Rajinder K, GRIZZLE, William E, VICKERS, Selwyn M, SALUJA, Ashok K

“…Pancreatic cancer is highly resistant to current chemotherapy agents. We therefore examined the effects of triptolide (a diterpenoid triepoxide) on pancreatic…”
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Elevated intracellular trypsin exacerbates acute pancreatitis and chronic pancreatitis in mice by Zhan, Xianbao, Wan, Jianhua, Zhang, Guowei, Song, Lele, Gui, Fu, Zhang, Yuebo, Li, Yinghua, Guo, Jia, Dawra, Rajinder K, Saluja, Ashok K, Haddock, Ashley N, Zhang, Lizhi, Bi, Yan, Ji, Baoan

“…Intra-acinar trypsinogen activation occurs in the earliest stages of pancreatitis and is believed to play important roles in pancreatitis pathogenesis…”
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Triptolide Induces Cell Death in Pancreatic Cancer Cells by Apoptotic and Autophagic Pathways by Mujumdar, Nameeta, Mackenzie, Tiffany N, Dudeja, Vikas, Chugh, Rohit, Antonoff, Mara B, Borja–Cacho, Daniel, Sangwan, Veena, Dawra, Rajinder, Vickers, Selwyn M, Saluja, Ashok K

“…Background & Aims Pancreatic adenocarcinoma, among the most lethal human malignancies, is resistant to current chemotherapies. We previously showed that…”
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Comprehensive analysis of microRNA signature of mouse pancreatic acini: overexpression of miR-21-3p in acute pancreatitis by Dixit, Ajay Kumar, Sarver, Anne E, Yuan, Zuobiao, George, John, Barlass, Usman, Cheema, Hassam, Sareen, Archana, Banerjee, Sulagna, Dudeja, Vikas, Dawra, Rajinder, Subramanian, Subbaya, Saluja, Ashok K

“…In the current study, we have characterized the global miRNA expression profile in mouse pancreatic acinar cells and during acute pancreatitis using…”
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Acute Pancreatitis: Bench to the Bedside by Pandol, Stephen J, Saluja, Ashok K, Imrie, Clement W, Banks, Peter A

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Development of a new mouse model of acute pancreatitis induced by administration of L-arginine by Dawra, Rajinder, Sharif, Rifat, Phillips, Phoebe, Dudeja, Vikas, Dhaulakhandi, Dhara, Saluja, Ashok K

“…The pathogenesis of acute pancreatitis is not fully understood. Experimental animal models that mimic human disease are essential to better understand the…”
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Evolution of novel therapeutic options for pancreatic cancer by Saluja, Ashok K, Dudeja, Vikas, Banerjee, Sulagna

“…PURPOSE OF REVIEWPancreatic cancer is the most devastating of all cancers with an extremely poor prognosis. In US alone, over 50 000 new cases of pancreatic…”
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Morphine worsens the severity and prevents pancreatic regeneration in mouse models of acute pancreatitis by Barlass, Usman, Dutta, Raini, Cheema, Hassam, George, John, Sareen, Archana, Dixit, Ajay, Yuan, Zuobiao, Giri, Bhuwan, Meng, Jingjing, Banerjee, Santanu, Banerjee, Sulagna, Dudeja, Vikas, Dawra, Rajinder K, Roy, Sabita, Saluja, Ashok K

“…Opioids such as morphine are widely used for the management of pain associated with acute pancreatitis. Interestingly, opioids are also known to affect the…”
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Why does pancreatic overstimulation cause pancreatitis? by Saluja, Ashok K, Lerch, Markus M, Phillips, Phoebe A, Dudeja, Vikas

“…Many animal models are available to investigate the pathogenesis of pancreatitis, an inflammatory disorder of the pancreas. However, the secretagogue…”
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Inhibition of Sp1 prevents ER homeostasis and causes cell death by lysosomal membrane permeabilization in pancreatic cancer by Dauer, Patricia, Gupta, Vineet K., McGinn, Olivia, Nomura, Alice, Sharma, Nikita S., Arora, Nivedita, Giri, Bhuwan, Dudeja, Vikas, Saluja, Ashok K., Banerjee, Sulagna

“…Endoplasmic reticulum (ER) stress initiates an important mechanism for cell adaptation and survival, named the unfolded protein response (UPR). Severe or…”
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Autophagy in pancreatic cancer: An emerging mechanism of cell death by Mujumdar, Nameeta, Saluja, Ashok K.

“…Pancreatic cancer, the fourth leading cause of cancer-related death in the United States, is resistant to current chemotherapies. Therefore, identification of…”
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