Search Results - "Saludes, P"

Multiple strain analysis of Streptomyces species from Philippine marine sediments reveals intraspecies heterogeneity in antibiotic activities by Tenebro, Chuckcris P., Trono, Dana Joanne Von L., Vicera, Carmela Vannette B., Sabido, Edna M., Ysulat, Jovito A., Macaspac, Aaron Joseph M., Tampus, Kimberly A., Fabrigar, Trisha Alexis P., Saludes, Jonel P., Dalisay, Doralyn S.

“…The marine ecosystem has become the hotspot for finding antibiotic-producing actinomycetes across the globe. Although marine-derived actinomycetes display…”
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Drug development from marine natural products by Molinski, Tadeusz F, Dalisay, Doralyn S, Lievens, Sarah L, Saludes, Jonel P

“…Key Points The large-scale collection, screening and discovery of novel marine natural products has propelled new chemical entities into the clinic for the…”
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Acute stressor exposure modifies plasma exosome-associated heat shock protein 72 (Hsp72) and microRNA (miR-142-5p and miR-203) by Beninson, Lida A, Brown, Peter N, Loughridge, Alice B, Saludes, Jonel P, Maslanik, Thomas, Hills, Abigail K, Woodworth, Tyler, Craig, Wendy, Yin, Hang, Fleshner, Monika

“…Exosomes, biologically active nanoparticles (40-100 nm) released by hematopoietic and non-hematopoietic cells, contain a variety of proteins and small,…”
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Marine-Derived Anticancer Agents Targeting Apoptotic Pathways: Exploring the Depths for Novel Cancer Therapies by Dalisay, Doralyn S, Tenebro, Chuckcris P, Sabido, Edna M, Suarez, Angelica Faith L, Paderog, Melissa June V, Reyes-Salarda, Rikka, Saludes, Jonel P

“…Extensive research has been conducted on the isolation and study of bioactive compounds derived from marine sources. Several natural products have demonstrated…”
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Nipah virus attachment glycoprotein stalk C-terminal region links receptor binding to fusion triggering by Liu, Qian, Bradel-Tretheway, Birgit, Monreal, Abrrey I, Saludes, Jonel P, Lu, Xiaonan, Nicola, Anthony V, Aguilar, Hector C

“…Membrane fusion is essential for paramyxovirus entry into target cells and for the cell-cell fusion (syncytia) that results from many paramyxoviral infections…”
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Anthracycline Shunt Metabolites From Philippine Marine Sediment-Derived Streptomyces Destroy Cell Membrane Integrity of Multidrug-Resistant Staphylococcus aureus by Paderog, Melissa June V, Suarez, Angelica Faith L, Sabido, Edna M, Low, Zhen Jie, Saludes, Jonel P, Dalisay, Doralyn S

“…The rise of antibiotic resistance (ABR) and the drying up of the pipeline for the development of new antibiotics demands an urgent search for new antibiotic…”
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Publisher Correction: Multiple strain analysis of Streptomyces species from Philippine marine sediments reveals intraspecies heterogeneity in antibiotic activities by Tenebro, Chuckcris P., Trono, Dana Joanne Von L., Vicera, Carmela Vannette B., Sabido, Edna M., Ysulat, Jovito A., Macaspac, Aaron Joseph M., Tampus, Kimberly A., Fabrigar, Trisha Alexis P., Saludes, Jonel P., Dalisay, Doralyn S.

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The Isorhamnetin-Containing Fraction of Philippine Honey Produced by the Stingless Bee Tetragonula biroi Is an Antibiotic against Multidrug-Resistant Staphylococcus aureus by Suarez, Angelica Faith L, Tirador, April Dawn G, Villorente, Zenith M, Bagarinao, Cathrina F, Sollesta, Jan Vincent N, Dumancas, Gerard G, Sun, Zhe, Zhan, Zhao Qi, Saludes, Jonel P, Dalisay, Doralyn S

“…Honey exhibits antibacterial and antioxidant activities that are ascribed to its diverse secondary metabolites. In the Philippines, the antibacterial and…”
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In response: Blood CO 2 exchange monitoring, Haldane effect and other calculations in sepsis and critical illness by Mesquida, J, Saludes, P, Espinal, C, Gruartmoner, G

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In response: Blood CO2 exchange monitoring, Haldane effect and other calculations in sepsis and critical illness by Mesquida, J., Saludes, P., Espinal, C., Gruartmoner, G.

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Insights into the Variation in Bioactivities of Closely Related Streptomyces Strains from Marine Sediments of the Visayan Sea against ESKAPE and Ovarian Cancer by Sabido, Edna M, Tenebro, Chuckcris P, Trono, Dana Joanne Von L, Vicera, Carmela Vannette B, Leonida, Sheeny Fane L, Maybay, Jose Jeffrey Wayne B, Reyes-Salarda, Rikka, Amago, Diana S, Aguadera, Angelica Marie V, Octaviano, May C, Saludes, Jonel P, Dalisay, Doralyn S

“…Marine sediments host diverse actinomycetes that serve as a source of new natural products to combat infectious diseases and cancer. Here, we report the…”
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Central venous-to-arterial carbon dioxide difference combined with arterial-to-venous oxygen content difference (PcvaCO2/CavO2) reflects microcirculatory oxygenation alterations in early septic shock by Mesquida, J., Espinal, C., Saludes, P., Cortés, E., Pérez-Madrigal, A., Gruartmoner, G.

“…To explore the relationship between central venous-to-arterial carbon dioxide difference (PcvaCO2), PcvaCO2/arterial-venous oxygen content difference ratio…”
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Branched dimerization of Tat peptide improves permeability to HeLa and hippocampal neuronal cells by Monreal, I Abrrey, Liu, Qian, Tyson, Katherine, Bland, Tyler, Dalisay, Doralyn S, Adams, Erin V, Wayman, Gary A, Aguilar, Hector C, Saludes, Jonel P

“…A dimeric branched peptide TATp-D designed as an analogue of the HIV-Tat protein transduction domain (TATp), a prototypical cell penetrating peptide (CPP),…”
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Potential of Natural Honey in Controlling Obesity and its Related Complications by Zulkifli, Muhammad Faiz, Radzi, Mohd Naim Fadhli Mohd, Saludes, Jonel P., Dalisay, Doralyn S., Ismail, Wan Iryani Wan

“…Honey has a long history of therapeutic properties for multiple diseases, including inflammation and oxidative stress. This review aimed to provide a better…”
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Clinically Isolated β-Lactam-Resistant Gram-Negative Bacilli in a Philippine Tertiary Care Hospital Harbor Multi-Class β-Lactamase Genes by Abordo, Alecks Megxel S, Carascal, Mark B, Remenyi, Roland, Dalisay, Doralyn S, Saludes, Jonel P

“…In the Philippines, data are scarce on the co-occurrence of multiple β-lactamases (BLs) in clinically isolated Gram-negative bacilli. To investigate this…”
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Evolution over a 15-year period of the clinical characteristics and outcomes of critically ill patients with severe community-acquired pneumonia by Vallés, J, Diaz, E, Martín-Loeches, I, Bacelar, N, Saludes, P, Lema, J, Gallego, M, Fontanals, D, Artigas, A

“…Abstract Objectives To study the characteristics and outcomes of patients in the ICU with severe community-acquired pneumonia (SCAP) over a 15-year…”
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Central venous-to-arterial carbon dioxide difference and the effect of venous hyperoxia: A limiting factor, or an additional marker of severity in shock? by Saludes, P., Proença, L., Gruartmoner, G., Enseñat, L., Pérez-Madrigal, A., Espinal, C., Mesquida, J.

“…Central venous-to-arterial carbon dioxide difference (P cva CO 2 ) has demonstrated its prognostic value in critically ill patients suffering from shock, and…”
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Visualization of renal rotenone accumulation after oral administration and in situ detection of kidney injury biomarkers via MALDI mass spectrometry imaging by Tenebro, Chuckcris P, Marcial, Neaven Bon Joy M, Salcepuedes, Janine J, Torrecampo, Josie C, Hernandez, Rajelle D, Francisco, John Alfon P, Infante, Kristine Mae G, Belardo, Veronica J, Paderes, Monissa C, Alvero, Rita Grace Y, Saludes, Jonel P, Dalisay, Doralyn S

“…The examination of drug accumulation within complex biological systems offers valuable insights into the molecular aspects of drug metabolism and toxicity…”
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Synergy between Genome Mining, Metabolomics, and Bioinformatics Uncovers Antibacterial Chlorinated Carbazole Alkaloids and Their Biosynthetic Gene Cluster from Streptomyces tubbatahanensis sp. nov., a Novel Actinomycete Isolated from Sulu Sea, Philippines by Tenebro, Chuckcris P, Trono, Dana Joanne V L, Balida, Lex Aliko P, Bayog, Leah Katrine A, Bruna, Julyanna R, Sabido, Edna M, Caspe, Dion Paul C, de Los Santos, Emmanuel Lorenzo C, Saludes, Jonel P, Dalisay, Doralyn S

“…In this study, a novel actinomycete strain, DSD3025 , isolated from the underexplored marine sediments in Tubbataha Reefs Natural Park, Sulu Sea, Philippines,…”
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Respiratory quotient estimations as additional prognostic tools in early septic shock by Mesquida, J., Saludes, P., Pérez-Madrigal, A., Proença, L., Cortes, E., Enseñat, L., Espinal, C., Gruartmoner, G.

“…Central venous-to-arterial carbon dioxide difference (P cva CO 2 ), and its correction by the arterial-to-venous oxygen content difference (P cva CO 2 /C av O…”
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