Search Results - "Salu, Philip"
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Nanocarrier mediated entinostat and oxaliplatin combination therapy displayed enhanced efficacy against pancreatic cancer
Published in Biomedicine & pharmacotherapy (01-06-2024)“…Pancreatic cancer is the third leading cause of cancer-related death in the United States, with a 5-year survival rate of only 12%. The poor prognosis of…”
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Abstract LB192: AGR2 knockdown reduces cell proliferation and increases endoplasmic reticulum proteotoxic stress in pancreatic cancer
Published in Cancer research (Chicago, Ill.) (05-04-2024)“…Abstract Pancreatic ductal adenocarcinoma (PDAC) is a highly lethal solid malignancy with low survival rates due to a dense stroma, abnormal gene expression…”
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AGR2 knockdown induces ER stress and mitochondria fission to facilitate pancreatic cancer cell death
Published in Biochimica et biophysica acta. Molecular cell research (01-01-2025)“…Anterior gradient 2 (AGR2) is often overexpressed in many human cancers, including pancreatic ductal adenocarcinoma (PDAC). Elevated AGR2 expression is known…”
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Advancements in Preclinical Models of Pancreatic Cancer
Published in Pancreas (01-02-2024)“…Pancreatic cancer remains one of the deadliest of all cancer types with a 5-year overall survival rate of just 12%. Preclinical models available for…”
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Mesenchymal stem cell-delivered paclitaxel nanoparticles exhibit enhanced efficacy against a syngeneic orthotopic mouse model of pancreatic cancer
Published in International journal of pharmaceutics (05-12-2024)“…[Display omitted] •Nano-MSCs were generated by incubating MSCs with drug-loaded nanoparticles.•Drug loading on MSCs was performed by endocytosis and surface…”
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Advancements in Circulating Tumor Cell Research: Bridging Biology and Clinical Applications
Published in Cancers (20-03-2024)“…Circulating tumor cells (CTCs) are cells released from the primary and metastatic tumor and intravasate into the blood or lymphatic vessels, where they are…”
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