Search Results - "Saltzman, Arneet L"
-
1
Regulation of alternative splicing by the core spliceosomal machinery
Published in Genes & development (15-02-2011)“…Alternative splicing (AS) plays a major role in the generation of proteomic diversity and in gene regulation. However, the role of the basal splicing machinery…”
Get full text
Journal Article -
2
Robotic microinjection enables large-scale transgenic studies of Caenorhabditis elegans
Published in Nature communications (14-10-2024)“…The nematode Caenorhabditis elegans is widely employed as a model organism to study basic biological mechanisms. However, transgenic C. elegans are generated…”
Get full text
Journal Article -
3
Regulation of Multiple Core Spliceosomal Proteins by Alternative Splicing-Coupled Nonsense-Mediated mRNA Decay
Published in Molecular and Cellular Biology (01-07-2008)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text
Journal Article -
4
Emerging Roles for Chromo Domain Proteins in Genome Organization and Cell Fate in C. elegans
Published in Frontiers in cell and developmental biology (23-10-2020)“…In most eukaryotes, the genome is packaged with histones and other proteins to form chromatin. One of the major mechanisms for chromatin regulation is through…”
Get full text
Journal Article -
5
Pathogenic bacteria modulate pheromone response to promote mating
Published in Nature (London) (12-01-2023)“…Pathogens generate ubiquitous selective pressures and host–pathogen interactions alter social behaviours in many animals 1 – 4 . However, very little is known…”
Get full text
Journal Article -
6
Mechanisms of epigenetic regulation by C. elegans nuclear RNA interference pathways
Published in Seminars in cell & developmental biology (01-07-2022)“…RNA interference (RNAi) is a highly conserved gene regulatory phenomenon whereby Argonaute/small RNA (AGO/sRNA) complexes target transcripts by antisense…”
Get full text
Journal Article -
7
Transgenerational Epigenetic Inheritance Is Negatively Regulated by the HERI-1 Chromodomain Protein
Published in Genetics (Austin) (01-12-2018)“…Transgenerational epigenetic inheritance (TEI) is the inheritance of epigenetic information for two or more generations. In most cases, TEI is limited to a…”
Get full text
Journal Article -
8
Multiple Histone Methyl-Lysine Readers Ensure Robust Development and Germline Immortality in Caenorhabditis elegans
Published in Genetics (Austin) (01-11-2018)“…Chromatin modifications, including methylation of histone H3 at lysine 27 (H3K27me) by the Polycomb group proteins, play a broadly conserved role in the…”
Get full text
Journal Article -
9
Technologies for the global discovery and analysis of alternative splicing
Published in Advances in experimental medicine and biology (2007)“…During the past approximately 20 years, studies on alternative splicing (AS) have largely been directed at the identification and characterization of factors…”
Get more information
Journal Article -
10
Analysis of Transgenerational Epigenetic Inheritance in C. elegans Using a Fluorescent Reporter and Chromatin Immunoprecipitation (ChIP)
Published in Journal of visualized experiments (05-05-2023)“…Transgenerational epigenetic inheritance (TEI) allows the transmission of information through the germline without changing the genome sequence, through…”
Get more information
Journal Article -
11
Microarray analysis of RNA processing and modification
Published in Methods in enzymology (2006)“…Most RNAs are processed from precursors by mechanisms that include covalent modifications, as well as the removal of flanking and intervening sequences…”
Get more information
Journal Article -
12
Quantitative microarray profiling provides evidence against widespread coupling of alternative splicing with nonsense-mediated mRNA decay to control gene expression
Published in Genes & development (15-01-2006)“…Sequence-based analyses have predicted that approximately 35% of mammalian alternative splicing (AS) events produce premature termination codon…”
Get full text
Journal Article -
13
Assessing the in vitro Binding Specificity of Histone Modification Reader Proteins Using Histone Peptide Arrays
Published in Bio-protocol (20-09-2021)“…In the field of chromatin biology, a major goal of understanding the roles of histone post-translational modifications is to identify the proteins and domains…”
Get full text
Journal Article -
14
Revealing Global Regulatory Features of Mammalian Alternative Splicing Using a Quantitative Microarray Platform
Published in Molecular cell (22-12-2004)“…We describe the application of a microarray platform, which combines information from exon body and splice-junction probes, to perform a quantitative analysis…”
Get full text
Journal Article -
15
Functional coordination of alternative splicing in the mammalian central nervous system
Published in Genome biology (12-06-2007)“…Alternative splicing (AS) functions to expand proteomic complexity and plays numerous important roles in gene regulation. However, the extent to which AS…”
Get full text
Journal Article -
16
Tools for Mos1-mediated single copy insertion (mosSCI) with excisable unc-119(+) or NeoR (G418) selection cassettes
Published in microPublication biology (27-08-2019)Get full text
Journal Article -
17
Regulation of Core Splicing Factors by Alternative Splicing and Nonsense-mediated mRNA Decay
Published 01-01-2011“…The majority of human genes are transcribed into a precursor messenger RNA (pre-mRNA) that is processed to produce multiple mRNA variants through alternative…”
Get full text
Dissertation