Search Results - "Salstrom, Jennifer L."
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Stochastic modeling reveals an evolutionary mechanism underlying elevated rates of childhood leukemia
Published in Proceedings of the National Academy of Sciences - PNAS (26-01-2016)“…Young children have higher rates of leukemia than young adults. This fact represents a fundamental conundrum, because hematopoietic cells in young children…”
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Intratumoral Injection of Clostridium novyi -NT Spores in Patients with Treatment-refractory Advanced Solid Tumors
Published in Clinical cancer research (01-01-2021)“…Intratumorally injected -NT (nontoxic; lacking the alpha toxin), an attenuated strain of , replicates within hypoxic tumor regions resulting in tumor-confined…”
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Pediatric patients who receive antibiotics for fever and neutropenia in less than 60min have decreased intensive care needs
Published in Pediatric blood & cancer (01-05-2015)“…BackgroundAntibiotic delivery to patients with fever and neutropenia (F&N) in <60 min is an increasingly important quality measure for oncology centers, but…”
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Pediatric patients who receive antibiotics for fever and neutropenia in less than 60 min have decreased intensive care needs
Published in Pediatric blood & cancer (01-05-2015)“…Background Antibiotic delivery to patients with fever and neutropenia (F&N) in <60 min is an increasingly important quality measure for oncology centers, but…”
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X-inactivation and the dynamic maintenance of gene silencing
Published in Molecular genetics and metabolism (01-09-2007)“…X-inactivation has long been a topic of fascination for educators, researchers, and clinicians alike. From complex patterns of inheritance to phenotypic…”
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Toddlers with anasarca and severe anemia: a lesson in preventive medicine
Published in Current opinion in pediatrics (01-02-2012)“…Two toddlers presented to their primary medical providers with anasarca and severe anemia. Laboratory evaluation revealed iron deficiency along with…”
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Genetic dissection of a rat model for rheumatoid arthritis : significant gender influences on autosomal modifier loci
Published in Human molecular genetics (22-09-2000)“…Rheumatoid arthritis (RA) is a common, chronic, autoimmune, inflammatory disease that is influenced by genetic factors including gender. Many studies suggest…”
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Stochastic modeling indicates that aging and somatic evolution in the hematopoietic system are driven by non-cell-autonomous processes
Published in Aging (Albany, NY.) (17-12-2014)“…Age-dependent tissue decline and increased cancer incidence are widely accepted to be rate-limited by the accumulation of somatic mutations over time. Current…”
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Localization of the Mutation Responsible for Osteopetrosis in the op Rat to a 1.5‐cM Genetic Interval on Rat Chromosome 10: Identification of Positional Candidate Genes by Radiation Hybrid Mapping
Published in Journal of bone and mineral research (01-10-2002)“…Osteopetrosis is caused by a heterogenous group of bone diseases that result in an increase in skeletal mass because of inadequate osteoclastic bone…”
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An Integrated Genetic Linkage Map with 1137 Markers Constructed from Five F2 Crosses of Autoimmune Disease-Prone and -Resistant Inbred Rat Strains
Published in Genomics (San Diego, Calif.) (15-01-2000)“…The rat (Rattus norvegicus) is an important experimental model for many human diseases including arthritis, diabetes, and other autoimmune and chronic…”
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Stochastic modeling indicates that aging and somatic evolution in the hematopoetic system are driven by non-cell-autonomous processes
Published in Aging (Albany, NY.) (01-12-2014)“…Age-dependent tissue decline and increased cancer incidence are widely accepted to be rate-limited by the accumulation of somatic mutations over time. Current…”
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Modulation of multiple experimental arthritis models by collagen‐induced arthritis quantitative trait loci isolated in congenic rat lines: Different effects of non–major histocompatibility complex quantitative trait loci in males and females
Published in Arthritis and rheumatism (01-08-2002)“…Objective Collagen‐induced arthritis (CIA) is a model of inflammatory arthritis with many similarities to rheumatoid arthritis (RA). We previously mapped in F2…”
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Genetic Variation in Rates of Nondisjunction: Association of Two Naturally Occurring Polymorphisms in the Chromokinesin nod With Increased Rates of Nondisjunction in Drosophila melanogaster
Published in Genetics (Austin) (01-08-1999)“…Genetic variation in nondisjunction frequency among X chromosomes from two Drosophila melanogaster natural populations is examined in a sensitized assay. A…”
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Genetic dissection of collagen-induced arthritis in Chromosome 10 quantitative trait locus speed congenic rats: evidence for more than one regulatory locus and sex influences
Published in Immunogenetics (New York) (01-09-2000)“…Rat Chromosome 10 (RNO10) harbors Cia5, a non-MHC quantitative trait locus (QTL) that regulates the severity of type II collagen-induced arthritis (CIA) in…”
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Polymorphisms of the tumor necrosis factor receptor type 1 locus among autoimmune susceptible and resistant inbred rat strains
Published in Immunogenetics (New York) (01-07-2001)“…Among inbred rat strains, susceptibility to and severity of autoimmune diseases varies dramatically. For example, DA/Bkl (DA), LEW/NHsd (LEW), and BB/(DR)/Wor…”
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