Myocardial involvement in coronavirus disease 19

Myocardial involvement in coronavirus disease 19

Background In late 2019, a cohort of patients presenting with pneumonia of unclear etiology in Wuhan, China, heralded the outbreak of coronavirus disease 19 (COVID-19). Previous severe acute respiratory syndrome (SARS) beta-coronavirus infections have been associated with tachyarrhythmias and signs...

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Bibliographic Details
Published in:Herz Vol. 45; no. 8; pp. 719 - 725
Main Authors: Saleh, Ahmed, Matsumori, Akira, Abdelrazek, Sherif, Eltaweel, Sara, Salous, Amjad, Neumann, Franz-Josef, Antz, Matthias
Format: Journal Article
Language:English
Published: Heidelberg Springer Medizin 01-12-2020
Springer Nature B.V
Subjects:
Adult
Betacoronavirus
Cardiology
Cardiovascular diseases
China - epidemiology
Congestive heart failure
Coronaviridae
Coronavirus
Coronavirus Infections - diagnosis
Coronavirus Infections - epidemiology
Coronaviruses
COVID-19
Epidemics
Etiology
Germany - epidemiology
Humans
Infections
Internal Medicine
Laboratories
Medicine
Medicine & Public Health
Myocardium - pathology
Original
Original Articles
Pandemics
Pneumonia, Viral
Prospective Studies
Respiratory diseases
SARS-CoV-2
Severe acute respiratory syndrome
Severe acute respiratory syndrome coronavirus 2
Signs and symptoms
Viral diseases
Viruses
China
Germany
COVID-19
NT-proBNP
Herz-Kreislauf-Erkrankung
Cardiovascular disease
SARS-CoV‑2
Kardiales Troponin T
Cardiac troponin T
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Summary:Background In late 2019, a cohort of patients presenting with pneumonia of unclear etiology in Wuhan, China, heralded the outbreak of coronavirus disease 19 (COVID-19). Previous severe acute respiratory syndrome (SARS) beta-coronavirus infections have been associated with tachyarrhythmias and signs and symptoms of heart failure. The emergence of SARS coronavirus 2 (SARS-CoV-2), which causes COVID-19, has rapidly developed into a pandemic, and a large number of infected patients have been reported to have underlying cardiovascular disease. Objective Since there are only scant published data regarding cardiovascular burden in the wake of viral epidemics, this study aimed to evaluate cardiac involvement in COVID-19. Material and methods This prospective cohort study included 40 adult inpatients at two centers in Germany. Adult patients diagnosed with COVID-19 in accordance with World Health Organization (WHO) interim guidance were included in the study, which focused on the potential cardiac involvement of SARS-CoV‑2. It was based on laboratory parameters as well as electro- and echocardiographic values to determine the impact of SARS-CoV‑2 virus on heart tissues. Results The conducted investigations confirmed the relationship between the presence of acute cardiac injury and COVID-19. Conclusion Myocardial injury and impaired myocardial function due to COVID-19 are common; however, no correlation was established between cardiac laboratory or echocardiographic values and mortality. Cardiovascular monitoring upon COVID-19 infection is crucial to determine the burden of cardiac involvement.
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ISSN:0340-9937
1615-6692
DOI:10.1007/s00059-020-05001-2