Search Results - "Salomon, David S"

Sulforaphane Suppresses the Growth of Triple-negative Breast Cancer Stem-like Cells In vitro and In vivo by Castro, Nadia P, Rangel, Maria C, Merchant, Anand S, MacKinnon, Gabriel, Cuttitta, Frank, Salomon, David S, Kim, Young S

“…Triple-negative breast cancer (TNBC) represents the poorest prognosis among all of breast cancer subtypes with no currently available effective therapy. In…”
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Role of Cripto-1 during Epithelial-to-Mesenchymal Transition in Development and Cancer by Rangel, Maria C, Karasawa, Hideaki, Castro, Nadia P, Nagaoka, Tadahiro, Salomon, David S, Bianco, Caterina

“…Epithelial-to-mesenchymal transition (EMT) is a critical multistep process that converts epithelial cells to more motile and invasive mesenchymal cells,…”
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A model of cancer stem cells derived from mouse induced pluripotent stem cells by Chen, Ling, Kasai, Tomonari, Li, Yueguang, Sugii, Yuh, Jin, Guoliang, Okada, Masashi, Vaidyanath, Arun, Mizutani, Akifumi, Satoh, Ayano, Kudoh, Takayuki, Hendrix, Mary J C, Salomon, David S, Fu, Li, Seno, Masaharu

“…Cancer stem cells (CSCs) are capable of continuous proliferation and self-renewal and are proposed to play significant roles in oncogenesis, tumor growth,…”
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Epidermal growth factor receptor (EGFR) signaling in cancer by Normanno, Nicola, De Luca, Antonella, Bianco, Caterina, Strizzi, Luigi, Mancino, Mario, Maiello, Monica R., Carotenuto, Adele, De Feo, Gianfranco, Caponigro, Francesco, Salomon, David S.

“…The epidermal growth factor receptor (EGFR) belongs to the ErbB family of receptor tyrosine kinases (RTK). These trans-membrane proteins are activated…”
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Role of Cripto-1 in Stem Cell Maintenance and Malignant Progression by Bianco, Caterina, Rangel, Maria Cristina, Castro, Nadia P, Nagaoka, Tadahiro, Rollman, Kelly, Gonzales, Monica, Salomon, David S

“…Cripto-1 is critical for early embryonic development and, together with its ligand Nodal, has been found to be associated with the undifferentiated status of…”
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CRIPTO1 expression in EGFR-mutant NSCLC elicits intrinsic EGFR-inhibitor resistance by Park, Kang-Seo, Raffeld, Mark, Moon, Yong Wha, Xi, Liqiang, Bianco, Caterina, Pham, Trung, Lee, Liam C, Mitsudomi, Tetsuya, Yatabe, Yasushi, Okamoto, Isamu, Subramaniam, Deepa, Mok, Tony, Rosell, Rafael, Luo, Ji, Salomon, David S, Wang, Yisong, Giaccone, Giuseppe

“…The majority of non-small cell lung cancer (NSCLC) patients harbor EGFR-activating mutations that can be therapeutically targeted by EGFR tyrosine kinase…”
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Different pancreatic cancer microenvironments convert iPSCs into cancer stem cells exhibiting distinct plasticity with altered gene expression of metabolic pathways by Hassan, Ghmkin, Ohara, Toshiaki, Afify, Said M, Kumon, Kazuki, Zahra, Maram H, Fu, Xiaoying, Al Kadi, Mohamad, Seno, Akimasa, Salomon, David S, Seno, Masaharu

“…Cancer stem cells (CSCs) are generated under irregular microenvironment in vivo, of which mimic is quite difficult due to the lack of enough information of the…”
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Whence CRIPTO: The Reemergence of an Oncofetal Factor in 'Wounds' That Fail to Heal by Freeman, David W, Rodrigues Sousa, Elisa, Karkampouna, Sofia, Zoni, Eugenio, Gray, Peter C, Salomon, David S, Kruithof-de Julio, Marianna, Spike, Benjamin T

“…There exists a set of factors termed oncofetal proteins that play key roles in ontogeny before they decline or disappear as the organism's tissues achieve…”
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Selenophosphate synthetase 1 is an essential protein with roles in regulation of redox homoeostasis in mammals by Tobe, Ryuta, Carlson, Bradley A, Huh, Jang Hoe, Castro, Nadia P, Xu, Xue-Ming, Tsuji, Petra A, Lee, Sang-Goo, Bang, Jeyoung, Na, Ji-Woon, Kong, Young-Yun, Beaglehole, Daniel, Southon, Eileen, Seifried, Harold, Tessarollo, Lino, Salomon, David S, Schweizer, Ulrich, Gladyshev, Vadim N, Hatfield, Dolph L, Lee, Byeong Jae

“…Selenophosphate synthetase (SPS) was initially detected in bacteria and was shown to synthesize selenophosphate, the active selenium donor. However, mammals…”
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Cripto-1 as a novel therapeutic target for triple negative breast cancer by Castro, Nadia P, Fedorova-Abrams, Natalie D, Merchant, Anand S, Rangel, Maria Cristina, Nagaoka, Tadahiro, Karasawa, Hideaki, Klauzinska, Malgorzata, Hewitt, Stephen M, Biswas, Kajal, Sharan, Shyam K, Salomon, David S

“…Triple-negative breast cancer (TNBC) presents the poorest prognosis among the breast cancer subtypes and no current standard therapy. Here, we performed an…”
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Tumor-associated macrophages derived from cancer stem cells by Osman, Amira, Oze, Miharu, Afify, Said M., Hassan, Ghmkin, EL-Ghlban, Samah, Nawara, Hend M., Fu, Xiaoying, Zahra, Maram Hussein, Seno, Akimasa, Winer, Ira, Salomon, David S., Seno, Masaharu

“…Macrophages are the most abundant immune cells in the microenvironment of solid tumors. The present study displayed histological and immunohistochemical…”
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Efficient drug delivery of Paclitaxel glycoside: a novel solubility gradient encapsulation into liposomes coupled with immunoliposomes preparation by Shigehiro, Tsukasa, Kasai, Tomonari, Murakami, Masaharu, Sekhar, Sreeja C, Tominaga, Yuki, Okada, Masashi, Kudoh, Takayuki, Mizutani, Akifumi, Murakami, Hiroshi, Salomon, David S, Mikuni, Katsuhiko, Mandai, Tadakatsu, Hamada, Hiroki, Seno, Masaharu

“…Although the encapsulation of paclitaxel into liposomes has been extensively studied, its significant hydrophobic and uncharged character has generated…”
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Adaptation of Laser Microdissection Technique for the Study of a Spontaneous Metastatic Mammary Carcinoma Mouse Model by NanoString Technologies by Castro, Nadia P, Merchant, Anand S, Saylor, Karen L, Anver, Miriam R, Salomon, David S, Golubeva, Yelena G

“…Laser capture microdissection (LCM) of tissue is an established tool in medical research for collection of distinguished cell populations under direct…”
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Exogenous Cripto-1 Suppresses Self-Renewal of Cancer Stem Cell Model by Alam, Md Jahangir, Takahashi, Ryota, Afify, Said M, Oo, Aung Ko Ko, Kumon, Kazuki, Nawara, Hend M, Khayrani, Aprilliana Cahya, Du, Juan, Zahra, Maram H, Seno, Akimasa, Salomon, David S, Seno, Masaharu

“…Cripto-1 is a glycophosphatidylinositol (GPI) anchored signaling protein of epidermal growth factor (EGF)-Cripto-1-FRL1-Cryptic (CFC) family and plays a…”
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Growth-associated protein 43–positive sensory nerve fibers accompanied by immature vessels are located in or near peritoneal endometriotic lesions by Mechsner, Sylvia, M.D, Schwarz, Jessica, Thode, Johanna, Loddenkemper, Christoph, M.D, Salomon, David S., Ph.D, Ebert, Andreas D., M.D., Ph.D

“…Objective To investigate the topographical relationship between nerve fibers and peritoneal endometriotic lesions and to determine the origin of…”
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Targeting the embryonic gene Cripto-1 in cancer and beyond by Bianco, Caterina, Salomon, David S

“…Emerging evidence has clearly implicated an inappropriate activation of embryonic regulatory genes during cell transformation in adult tissues. An example of…”
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Cripto‐1 Is a Cell Surface Marker for a Tumorigenic, Undifferentiated Subpopulation in Human Embryonal Carcinoma Cells by Watanabe, Kazuhide, Meyer, Matthew J., Strizzi, Luigi, Lee, Joseph M., Gonzales, Monica, Bianco, Caterina, Nagaoka, Tadahiro, Farid, Shahram S., Margaryan, Naira, Hendrix, Mary J.C., Vonderhaar, Barbara K., Salomon, David S.

“…Deregulation of stem cells is associated with the generation and progression of malignant tumors. In addition, genes that are associated with early…”
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Embryonic stem cells are redirected to non-tumorigenic epithelial cell fate by interaction with the mammary microenvironment by Boulanger, Corinne A, Bruno, Robert D, Mack, David L, Gonzales, Monica, Castro, Nadia P, Salomon, David S, Smith, Gilbert H

“…Experiments were conducted to redirect mouse Embryonic Stem (ES) cells from a tumorigenic phenotype to a normal mammary epithelial phenotype in vivo. Mixing…”
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Requirement of Glycosylphosphatidylinositol Anchor of Cripto-1 for trans Activity as a Nodal Co-receptor by Watanabe, Kazuhide, Hamada, Shin, Bianco, Caterina, Mancino, Mario, Nagaoka, Tadahiro, Gonzales, Monica, Bailly, Veronique, Strizzi, Luigi, Salomon, David S.

“…Cripto-1 (CR-1) has an indispensable role as a Nodal co-receptor for patterning of body axis in embryonic development. CR-1 is reported to have a paracrine…”
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Potential for Cripto-1 in defining stem cell-like characteristics in human malignant melanoma by Strizzi, Luigi, Abbott, Daniel E., Salomon, David S., Hendrix, Mary J.C.

“…The diagnosis of melanoma is becoming ever more frequent. Although surgical excision of early lesions is associated with relatively significant high cure…”
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