Search Results - "Salome, Cheryl"

Physiology of obesity and effects on lung function by Salome, Cheryl M, King, Gregory G, Berend, Norbert

“…1 Woolcock Institute of Medical Research, Glebe; ; 2 University of Sydney, Sydney; and ; 3 Department of Respiratory Medicine, Royal North Shore Hospital, St…”
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Asthma and obesity: A known association but unknown mechanism by FARAH, CLAUDE S., SALOME, CHERYL M.

“…ABSTRACT The obese asthma phenotype is an increasingly common encounter in our clinical practice. Epidemiological data indicate that obesity increases the…”
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The role of the small airways in the clinical expression of asthma in adults by Farah, Claude S., MBBS, King, Gregory G., MBChB, PhD, Brown, Nathan J., PhD, Downie, Sue R., PhD, Kermode, Jessica A., BSc (Hons1), Hardaker, Kate M., BSc, Peters, Matthew J., MD, Berend, Norbert, MD, Salome, Cheryl M., PhD

“…Background The clinical relevance of increased ventilation heterogeneity, a marker of small-airways disease, in asthmatic patients is unclear. Ventilation…”
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The effect of low lung volume on airway function in obesity by Mahadev, Sriram, Salome, Cheryl M, Berend, Norbert, King, Gregory G

“…Highlights • Obesity is associated with reduced operating lung volume. • Breathing at low operating lung volume leads to airway closure during tidal breathing…”
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Peripheral airway dysfunction and relationship with symptoms in smokers with preserved spirometry by Jetmalani, Kanika, Thamrin, Cindy, Farah, Claude S., Bertolin, Amy, Chapman, David G., Berend, Norbert, Salome, Cheryl M., King, Gregory G.

“…ABSTRACT Background and objective Smokers develop respiratory symptoms and peripheral airway dysfunction even when spirometry is preserved. Multiple breath…”
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Ventilation heterogeneity predicts asthma control in adults following inhaled corticosteroid dose titration by Farah, Claude S., MBBS, King, Gregory G., MBChB, PhD, Brown, Nathan J., PhD, Peters, Matthew J., MD, Berend, Norbert, MD, Salome, Cheryl M., PhD

“…Background Asthma guidelines recommend inhaled corticosteroid (ICS) dose titration for patients on the basis of an assessment of current asthma control…”
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Peripheral ventilation heterogeneity determines the extent of bronchoconstriction in asthma by Farrow, Catherine E, Salome, Cheryl M, Harris, Benjamin E, Bailey, Dale L, Berend, Norbert, King, Gregory G

“…In asthma, bronchoconstriction causes topographically heterogeneous airway narrowing, as measured by three-dimensional ventilation imaging. Computation…”
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Obesity Is a Determinant of Asthma Control Independent of Inflammation and Lung Mechanics by Farah, Claude S., MBBS, Kermode, Jessica A., BSc(Hons1), Downie, Sue R., PhD, Brown, Nathan J., PhD, Hardaker, Kate M., BSc, Berend, Norbert, MD, FCCP, King, Gregory G., MBChB, PhD, Salome, Cheryl M., PhD

“…Background It is unclear why obesity is associated with worse asthma control. We hypothesized that (1) obesity affects asthma control independent of…”
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The Relationship Between Airflow Obstruction, Emphysema Extent, and Small Airways Function in COPD by Timmins, Sophie C., MBBS (Hons 1), Diba, Chantale, PhD, Farrow, Catherine E., BSpSc, Schoeffel, Robin E., MHSc, Berend, Norbert, MD, FCCP, Salome, Cheryl M., PhD, King, Gregory G., PhD

“…Background The severities of COPD (FEV1 % predicted) and airflow obstruction (FEV1 /FVC) are considered to be due to both emphysema and small airways disease…”
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Ventilation heterogeneity is a major determinant of airway hyperresponsiveness in asthma, independent of airway inflammation by Downie, Sue R, Salome, Cheryl M, Verbanck, Sylvia, Thompson, Bruce, Berend, Norbert, King, Gregory G

“…Background: Airway hyperresponsiveness is the ability of airways to narrow excessively in response to inhaled stimuli and is a key feature of asthma. Airway…”
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Effect of methacholine on peripheral lung mechanics and ventilation heterogeneity in asthma by Downie, Sue R, Salome, Cheryl M, Verbanck, Sylvia, Thompson, Bruce R, Berend, Norbert, King, Gregory G

“…The forced oscillation technique (FOT) and multiple-breath nitrogen washout (MBNW) are noninvasive tests that are potentially sensitive to peripheral airways,…”
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Airway closure on imaging relates to airway hyperresponsiveness and peripheral airway disease in asthma by Farrow, Catherine E, Salome, Cheryl M, Harris, Benjamin E, Bailey, Dale L, Bailey, Elizabeth, Berend, Norbert, Young, Iven H, King, Gregory G

“…The regional pattern and extent of airway closure measured by three-dimensional ventilation imaging may relate to airway hyperresponsiveness (AHR) and…”
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Obesity, expiratory flow limitation and asthma symptoms by Mahadev, Sriram, Farah, Claude S, King, Gregory G, Salome, Cheryl M

“…Abstract Obesity is associated with poor asthma control, but the reason for this is unclear. Reduction in operating lung volume, as occurs in obesity, and…”
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Predictors of Airway Hyperresponsiveness Differ Between Old and Young Patients With Asthma by Hardaker, Kate M., BSc, Downie, Sue R., PhD, Kermode, Jessica A., BSc (Hons1), Farah, Claude S., MBBS, Brown, Nathan J., PhD, Berend, Norbert, MD, FCCP, King, Gregory G., PhD, Salome, Cheryl M., PhD

“…Background Age-related increases in morbidity and mortality due to asthma may be due to changes in pathophysiology as patients with asthma get older. There is…”
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Airway Distensibility in Adults with Asthma and Healthy Adults, Measured by Forced Oscillation Technique by Brown, Nathan J, Salome, Cheryl M, Berend, Norbert, Thorpe, C. William, King, Gregory G

“…Reduced airway distensibility in subjects with asthma compared with control subjects may be related to differences in lung elastic recoil and bronchomotor…”
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Changes in oscillatory impedance and nitrogen washout with combination fluticasone/salmeterol therapy in COPD by Timmins, Sophie C, Diba, Chantale, Schoeffel, Robin E, Salome, Cheryl M, King, Gregory G, Thamrin, Cindy

“…Summary Introduction Combination inhaled corticosteroid/long-acting bronchodilator (ICS/LABA) therapy reduces the exacerbation rate and improves spirometry and…”
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Expiratory flow limitation relates to symptoms during COPD exacerbations requiring hospital admission by Jetmalani, Kanika, Timmins, Sophie, Brown, Nathan J, Diba, Chantale, Berend, Norbert, Salome, Cheryl M, Wen, Fu-Qiang, Chen, Peng, King, Gregory G, Farah, Claude S

“…Expiratory flow limitation (EFL) is seen in some patients presenting with a COPD exacerbation; however, it is unclear how EFL relates to the clinical features…”
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Mechanisms of airway hyperresponsiveness in asthma by BEREND, Norbert, SALOME, Cheryl M., KING, Greg G.

“…:  Airway hyperresponsiveness (AHR) is a fundamental abnormality in asthma. There are many potential factors contributing to the excessive airway response…”
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Predictive markers of asthma exacerbation during stepwise dose reduction of inhaled corticosteroids by LEUPPI, Jörg D, SALOME, Cheryl M, CHAN, Hak-Kim, WOOLCOCK, Ann J, JENKINS, Christine R, ANDERSON, Sandra D, WEI XUAN, MARKS, Guy B, KOSKELA, Heikki, BRANNAN, John D, FREED, Ruth, ANDERSSON, Morgan

“…To determine predictors for failed reduction of inhaled corticosteroids (ICS), in 50 subjects with well-controlled asthma (age 43.7 [18-69]; 22 males) taking a…”
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Day-to-day variability of oscillatory impedance and spirometry in asthma and COPD by Timmins, Sophie C, Coatsworth, Nicholas, Palnitkar, Gaurie, Thamrin, Cindy, Farrow, Catherine E, Schoeffel, Robin E, Berend, Norbert, Diba, Chantale, Salome, Cheryl M, King, Gregory G

“…Highlights ► Impedance measured by FOT is highly repeatable in health, asthma, and COPD. ► Repeatability of total and inspiratory components of Rrs and Xrs in…”
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