Search Results - "Salom, Barbara"

Establishment and genomic characterization of the new chordoma cell line Chor-IN-1 by Bosotti, Roberta, Magnaghi, Paola, Di Bella, Sebastiano, Cozzi, Liviana, Cusi, Carlo, Bozzi, Fabio, Beltrami, Nicola, Carapezza, Giovanni, Ballinari, Dario, Amboldi, Nadia, Lupi, Rosita, Somaschini, Alessio, Raddrizzani, Laura, Salom, Barbara, Galvani, Arturo, Stacchiotti, Silvia, Tamborini, Elena, Isacchi, Antonella

“…Chordomas are rare, slowly growing tumors with high medical need, arising in the axial skeleton from notochord remnants. The transcription factor “brachyury”…”
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Afatinib Is a New Therapeutic Approach in Chordoma with a Unique Ability to Target EGFR and Brachyury by Magnaghi, Paola, Salom, Barbara, Cozzi, Liviana, Amboldi, Nadia, Ballinari, Dario, Tamborini, Elena, Gasparri, Fabio, Montagnoli, Alessia, Raddrizzani, Laura, Somaschini, Alessio, Bosotti, Roberta, Orrenius, Christian, Bozzi, Fabio, Pilotti, Silvana, Galvani, Arturo, Sommer, Josh, Stacchiotti, Silvia, Isacchi, Antonella

“…Chordomas are rare bone tumors with no approved therapy. These tumors express several activated tyrosine kinase receptors, which prompted attempts to treat…”
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Stereoselective synthesis of 3,4‐dihydropyrrolo[1,2‐a]pyrazin‐1(2H)‐one derivatives as PIM kinase inhibitors inspired from marine alkaloids by Casuscelli, Francesco, Ardini, Elena, Avanzi, Nilla, Badari, Alessandra, Casale, Elena, Disingrini, Teresa, Donati, Daniele, Ermoli, Antonella, Felder, Eduard R., Galvani, Arturo, Isacchi, Antonella, Menichincheri, Maria, Montemartini, Marisa, Orrenius, Christian, Piutti, Claudia, Salom, Barbara, Papeo, Gianluca

“…We previously demonstrated that natural product‐inspired 3,4‐dihydropyrrolo[1,2‐a]pyrazin‐1(2H)‐ones derivatives delivered potent and selective PIM kinases…”
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Stereoselective synthesis of 3,4‐dihydropyrrolopyrazin‐1(2H)‐one derivatives as PIM kinase inhibitors inspired from marine alkaloids by Casuscelli, Francesco, Ardini, Elena, Avanzi, Nilla, Badari, Alessandra, Casale, Elena, Disingrini, Teresa, Donati, Daniele, Ermoli, Antonella, Felder, Eduard R, Galvani, Arturo, Isacchi, Antonella, Menichincheri, Maria, Montemartini, Marisa, Orrenius, Christian, Piutti, Claudia, Salom, Barbara, Papeo, Gianluca

“…We previously demonstrated that natural product‐inspired 3,4‐dihydropyrrolo[1,2‐a]pyrazin‐1(2H)‐ones derivatives delivered potent and selective PIM kinases…”
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Discovery and optimization of pyrrolo[1,2-a]pyrazinones leads to novel and selective inhibitors of PIM kinases by Casuscelli, Francesco, Ardini, Elena, Avanzi, Nilla, Casale, Elena, Cervi, Giovanni, D’Anello, Matteo, Donati, Daniele, Faiardi, Daniela, Ferguson, Ronald D., Fogliatto, Gianpaolo, Galvani, Arturo, Marsiglio, Aurelio, Mirizzi, Danilo G., Montemartini, Marisa, Orrenius, Christian, Papeo, Gianluca, Piutti, Claudia, Salom, Barbara, Felder, Eduard R.

“…A novel series of PIM inhibitors was derived from a combined effort in natural product-inspired library generation and screening. The novel…”
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Discovery of 2‑(Cyclohexylmethylamino)pyrimidines as a New Class of Reversible Valosine Containing Protein Inhibitors by Cervi, Giovanni, Magnaghi, Paola, Asa, Daniela, Avanzi, Nilla, Badari, Alessandra, Borghi, Daniela, Caruso, Michele, Cirla, Alessandra, Cozzi, Liviana, Felder, Eduard, Galvani, Arturo, Gasparri, Fabio, Lomolino, Antonio, Magnuson, Steven, Malgesini, Beatrice, Motto, Ilaria, Pasi, Maurizio, Rizzi, Simona, Salom, Barbara, Sorrentino, Graziella, Troiani, Sonia, Valsasina, Barbara, O’Brien, Thomas, Isacchi, Antonella, Donati, Daniele, D’Alessio, Roberto

“…Valosine-containing protein (VCP), also known as p97 or cdc48 in yeast, is a highly abundant protein belonging to the AAA ATPase family involved in a number of…”
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Abstract 74: Establishment and characterization of the new sacral chordoma cell line Chor-IN-1 by Magnaghi, Paola, Bosotti, Roberta, Amboldi, Nadia, Cozzi, Liviana, Somaschini, Alessio, Stacchiotti, Silvia, Bozzi, Fabio, Tamborini, Elena, Conca, Elena, Pilotti, Silvana, Pierotti, Marco A., Di Bella, Sebastiano, Cusi, Carlo, Ballinari, Dario, Galvani, Arturo, Salom, Barbara, Isacchi, Antonella

“…Abstract Chordomas are rare, slowly growing but locally invasive bone tumors, derived from notocord remnants and characterized by the expression of “Brachyury”…”
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The generation of purinome-targeted libraries as a means to diversify ATP-mimetic chemical classes for lead finding by Felder, Eduard R., Badari, Alessandra, Disingrini, Teresa, Mantegani, Sergio, Orrenius, Christian, Avanzi, Nilla, Isacchi, Antonella, Salom, Barbara

“…The generation of novel chemotypes in support of our oncology research projects expanded in recent years from a canonical design of kinase-targeted compound…”
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A new method for the solution and solid phase synthesis of chiral β-sulfonopeptides under mild conditions by Gude, Markus, Piarulli, Umberto, Potenza, Donatella, Salom, Barbara, Gennari, Cesare

“…Chiral β-sulfonopeptides were synthesized both in solution and in the solid phase using the sulfonyl chlorides derived from enantiomerically pure 2-substituted…”
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Hotel housekeepers and occupational health: experiences and perceived risks by Chela-Alvarez, Xènia, Bulilete, Oana, Garcia-Illan, Encarna, Vidal-Thomàs, MClara, Llobera, Joan

“…BackgroundHotel housekeepers are one of the most important occupational group within tourism hotel sector; various health problems related to their job have…”
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Synthesis of Combinatorial Libraries of Vinylogous Sulfonamidopeptides (vs-Peptides) by Gennari, Cesare, Longari, Chiara, Ressel, Stefano, Salom, Barbara, Piarulli, Umberto, Ceccarelli, Simona, Mielgo, Antonia

“…Chiral vinylogous sulfonamidopeptides (vs‐peptides) were synthesized on TentaGel resin employing (S)‐ and (R)‐N‐Boc‐vinylogous sulfonyl chlorides 2a–i as…”
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Synthesis of Chiral Vinylogous Sulfonamidopeptides (vs-Peptides) by Gennari, Cesare, Longari, Chiara, Ressel, Stefano, Salom, Barbara, Mielgo, Antonia

“…Chiral vinylogous amino sulfonic acids (vs‐amino acids) were synthesized starting from either L‐ or D‐α‐amino acids via N‐Boc–α‐amino aldehydes. Wittig‐Horner…”
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