Search Results - "Salmons, Brian"

Oncogenic Viruses and Breast Cancer: Mouse Mammary Tumor Virus (MMTV), Bovine Leukemia Virus (BLV), Human Papilloma Virus (HPV), and Epstein-Barr Virus (EBV) by Lawson, James S, Salmons, Brian, Glenn, Wendy K

“…Although the risk factors for breast cancer are well established, namely female gender, early menarche and late menopause plus the protective influence of…”
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The Role of a Betaretrovirus in Human Breast Cancer: Enveloping a Conundrum by Gunzburg, Walter H, Salmons, Brian

“…Most of the evidence that a human betaretrovirus (HBRV/HMTV) highly related to mouse mammary tumour virus (MMTV) has an etiological role in breast cancer has…”
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Long-Term Survival of Cellulose Sulphate-Encapsulated Cells and Metronomic Ifosfamide Control Tumour Growth in Pancreatic Cancer Models-A Prelude to Treating Solid Tumours Effectively in Pets and Humans by Salmons, Brian, Gunzburg, Walter H

“…The use of encapsulated cells for the in vivo delivery of biotherapeutics is a promising new technology to potentiate the effectiveness of cell-based therapies…”
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Efficient protection of microorganisms for delivery to the intestinal tract by cellulose sulphate encapsulation by Gunzburg, Walter H, Aung, Myo Myint, Toa, Pauline, Ng, Shirelle, Read, Eliot, Tan, Wee Jin, Brandtner, Eva Maria, Dangerfield, John, Salmons, Brian

“…Abstract Background Gut microbiota in humans and animals play an important role in health, aiding in digestion, regulation of the immune system and protection…”
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Recent developments linking retroviruses to human breast cancer: infectious agent, enemy within or both? by Salmons, Brian, Lawson, James S, Günzburg, Walter H

“…Evidence is accumulating that one or more beta-retrovirus is associated with human breast cancer. Retroviruses can exist as an infectious (exogenous) virus or…”
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Semipermeable Cellulose Beads Allow Selective and Continuous Release of Small Extracellular Vesicles (sEV) From Encapsulated Cells by Zavala, Gabriela, Ramos, María-Paz, Figueroa-Valdés, Aliosha I., Cisternas, Pablo, Wyneken, Ursula, Hernández, Macarena, Toa, Pauline, Salmons, Brian, Dangerfield, John, Gunzburg, Walter H., Khoury, Maroun

“…The clinical benefit of therapies using Mesenchymal Stem Cells (MSCs) is attributable to their pleiotropic effect over cells and tissues, mainly through their…”
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Mouse Mammary Tumor Virus Integration Site Selection in Human and Mouse Genomes by FASCHINGER, Alexander, ROUAULT, Francoise, SOLLNER, Johannes, LUKAS, Arno, SALMONS, Brian, GÜNZBURG, Walter H, INDIK, Stanislav

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Correction of distortion due to thermal drift in scanning probe microscopy by Salmons, Brian S., Katz, Daniel R., Trawick, Matthew L.

“…A common source of distortion in scanning probe microscope (SPM) images is “thermal drift,” the slow thermal expansion of different materials in the sample and…”
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Phase I/II clinical trial of encapsulated, cytochrome P450 expressing cells as local activators of cyclophosphamide to treat spontaneous canine tumours by Michałowska, Monika, Winiarczyk, Stanislaw, Adaszek, Łukasz, Łopuszyński, Wojciech, Grądzki, Zbigniew, Salmons, Brian, Günzburg, Walter H

“…Based upon promising preclinical studies, a clinical trial was performed in which encapsulated cells overexpressing cytochrome P450 enzyme isoform 2B1 were…”
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Evaluation of a gene-directed enzyme-product therapy (GDEPT) in human pancreatic tumor cells and their use as in vivo models for pancreatic cancer by Hlavaty, Juraj, Petznek, Helga, Holzmüller, Harry, Url, Angelika, Jandl, Gerrit, Berger, André, Salmons, Brian, Günzburg, Walter H, Renner, Matthias

“…Gene-directed enzyme prodrug therapy (GDEPT) is a two-step treatment protocol for solid tumors that involves the transfer of a gene encoding a…”
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Rapid spread of mouse mammary tumor virus in cultured human breast cells by Indik, Stanislav, Günzburg, Walter H, Kulich, Pavel, Salmons, Brian, Rouault, Francoise

“…The role of mouse mammary tumor virus (MMTV) as a causative agent in human breast carcinogenesis has recently been the subject of renewed interest. The…”
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Human Endogenous Retroviral Long Terminal Repeat Sequences as Cell Type-Specific Promoters in Retroviral Vectors by SCHÖN, Ulrike, DIEM, Olivia, LEITNER, Laura, GÜNZBURG, Walter H, MAGER, Dixie L, SALMONS, Brian, LEIB-MÖSCH, Christine

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Comparative evaluation of preclinical in vivo models for the assessment of replicating retroviral vectors for the treatment of glioblastoma by Hlavaty, Juraj, Jandl, Gerrit, Liszt, Melissa, Petznek, Helga, König-Schuster, Marielle, Sedlak, Jenny, Egerbacher, Monika, Weissenberger, Jakob, Salmons, Brian, Günzburg, Walter H., Renner, Matthias

“…Despite impressive improvements in neurosurgical techniques, radiation and chemotherapy during the past few years, little progress has been made in the…”
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Small agarose microcapsules with cell-enclosing hollow core for cell therapy: transplantation of Ifosfamide-activating cells to the mice with preestablished subcutaneous tumor by Sakai, Shinji, Hashimoto, Ichiro, Tanaka, Shinji, Salmons, Brian, Kawakami, Koei

“…Cell transplantation after enclosing in microcapsules has been studied as an alternative approach for treatment of wide variety of diseases. In the present…”
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Encapsulated cells expressing a chemotherapeutic activating enzyme allow the targeting of subtoxic chemotherapy and are safe and efficacious: data from two clinical trials in pancreatic cancer by Löhr, J Matthias, Haas, Stephan L, Kröger, Jens C, Friess, Helmut M, Höft, Raimund, Goretzki, Peter E, Peschel, Christian, Schweigert, Markus, Salmons, Brian, Gunzburg, Walter H

“…Despite progress in the treatment of pancreatic cancer, there is still a need for improved therapies. In this manuscript, we report clinical experience with a…”
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A year in review and looking to the future by Salmons, Brian, Langa, Arturo

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Tissue- and Tumor-Specific Targeting of Murine Leukemia Virus-Based Replication-Competent Retroviral Vectors by METZL, Christian, MISCHEK, Daniela, SALMONS, Brian, GÜNZBURG, Walter H, RENNER, Matthias, PORTSMOUTH, Daniel

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Effects of Viral Strain, Transgene Position, and Target Cell Type on Replication Kinetics, Genomic Stability, and Transgene Expression of Replication-Competent Murine Leukemia Virus-Based Vectors by PAAR, Matthias, SCHWAB, Sonja, ROSENFELLNER, Doris, SALMONS, Brian, GÜNZBURG, Walter H, RENNER, Matthias, PORTSMOUTH, Daniel

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Treatment of inoperable pancreatic carcinoma using a cell-based local chemotherapy: results of a phase I/II clinical trial by Salmons, Brian, Löhr, Matthias, Günzburg, Walter H

“…The use of ifosfamide for conventional chemotherapy of pancreatic tumors is limited by systemic toxicity caused, in part, by its activation by liver-specific…”
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Subsieve-size agarose capsules enclosing ifosfamide-activating cells: a strategy toward chemotherapeutic targeting to tumors by Sakai, Shinji, Kawabata, Kenji, Tanaka, Shinji, Harimoto, Norifumi, Hashimoto, Ichiro, Mu, Changjun, Salmons, Brian, Ijima, Hiroyuki, Kawakami, Koei

“…Localized activation of the prodrug ifosfamide in or close to tumors by implanting encapsulated ifosfamide-activating cells is an efficacious strategy for…”
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