Search Results - "Salminen, Marjo"

Seroprevalence and SARS-CoV-2 cross-reactivity of endemic coronavirus OC43 and 229E antibodies in Finnish children and adults by Tamminen, Kirsi, Salminen, Marjo, Blazevic, Vesna

“…Endemic human coronaviruses (hCoVs) are common causative agents of respiratory tract infections, affecting especially children. However, in the ongoing…”
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Matrix stiffness controls lymphatic vessel formation through regulation of a GATA2-dependent transcriptional program by Frye, Maike, Taddei, Andrea, Dierkes, Cathrin, Martinez-Corral, Ines, Fielden, Matthew, Ortsäter, Henrik, Kazenwadel, Jan, Calado, Dinis P., Ostergaard, Pia, Salminen, Marjo, He, Liqun, Harvey, Natasha L., Kiefer, Friedemann, Mäkinen, Taija

“…Tissue and vessel wall stiffening alters endothelial cell properties and contributes to vascular dysfunction. However, whether extracellular matrix (ECM)…”
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Mechanisms regulating GABAergic neuron development by Achim, Kaia, Salminen, Marjo, Partanen, Juha

“…Neurons using gamma-aminobutyric acid (GABA) as their neurotransmitter are the main inhibitory neurons in the mature central nervous system (CNS) and show…”
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Gata2 and Gata3 regulate the differentiation of serotonergic and glutamatergic neuron subtypes of the dorsal raphe by Haugas, Maarja, Tikker, Laura, Achim, Kaia, Salminen, Marjo, Partanen, Juha

“…Serotonergic and glutamatergic neurons of the dorsal raphe regulate many brain functions and are important for mental health. Their functional diversity is…”
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GATA2 is required for lymphatic vessel valve development and maintenance by Kazenwadel, Jan, Betterman, Kelly L, Chong, Chan-Eng, Stokes, Philippa H, Lee, Young K, Secker, Genevieve A, Agalarov, Yan, Demir, Cansaran Saygili, Lawrence, David M, Sutton, Drew L, Tabruyn, Sebastien P, Miura, Naoyuki, Salminen, Marjo, Petrova, Tatiana V, Matthews, Jacqueline M, Hahn, Christopher N, Scott, Hamish S, Harvey, Natasha L

“…Heterozygous germline mutations in the zinc finger transcription factor GATA2 have recently been shown to underlie a range of clinical phenotypes, including…”
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Rotavirus epidemiology 5-6 years after universal rotavirus vaccination: persistent rotavirus activity in older children and elderly by Markkula, Jukka, Hemming-Harlo, Maria, Salminen, Marjo T., Savolainen-Kopra, Carita, Pirhonen, Jaana, al-Hello, Haider, Vesikari, Timo

“…Background: Rotavirus (RV) vaccination using RotaTeq ® vaccine exclusively was introduced into Finnish National Immunization Program (NIP) in 2009, and soon…”
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Gata2 is required for the development of inner ear semicircular ducts and the surrounding perilymphatic space by Haugas, Maarja, Lilleväli, Kersti, Hakanen, Janne, Salminen, Marjo

“…Gata2 has essential roles in the development of many organs. During mouse inner ear morphogenesis, it is expressed in otic vesicle and the surrounding periotic…”
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Loss of the Hematopoietic Stem Cell Factor GATA2 in the Osteogenic Lineage Impairs Trabecularization and Mechanical Strength of Bone by Tolkachov, Alexander, Fischer, Cornelius, Ambrosi, Thomas H., Bothe, Melissa, Han, Chung-Ting, Muenzner, Matthias, Mathia, Susanne, Salminen, Marjo, Seifert, Georg, Thiele, Mario, Duda, Georg N., Meijsing, Sebastiaan H., Sauer, Sascha, Schulz, Tim J., Schupp, Michael

“…The transcription factor GATA2 is required for expansion and differentiation of hematopoietic stem cells (HSCs). In mesenchymal stem cells (MSCs), GATA2 blocks…”
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Gata2 is a tissue-specific post-mitotic selector gene for midbrain GABAergic neurons by Kala, Kaia, Haugas, Maarja, Lilleväli, Kersti, Guimera, Jordi, Wurst, Wolfgang, Salminen, Marjo, Partanen, Juha

“…Midbrain GABAergic neurons control several aspects of behavior, but regulation of their development and diversity is poorly understood. Here, we further refine…”
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Cyclase-associated protein 1 (CAP1) promotes cofilin-induced actin dynamics in mammalian nonmuscle cells by Bertling, Enni, Hotulainen, Pirta, Mattila, Pieta K, Matilainen, Tanja, Salminen, Marjo, Lappalainen, Pekka

“…Cyclase-associated proteins (CAPs) are highly conserved actin monomer binding proteins present in all eukaryotes. However, the mechanism by which CAPs…”
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ABBA regulates plasma-membrane and actin dynamics to promote radial glia extension by Saarikangas, Juha, Hakanen, Janne, Mattila, Pieta K, Grumet, Martin, Salminen, Marjo, Lappalainen, Pekka

“…Radial glia play key roles in neuronal migration, axon guidance, and neurogenesis during development of the central nervous system. However, the molecular…”
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Mouse MIM, a Tissue-specific Regulator of Cytoskeletal Dynamics, Interacts with ATP-Actin Monomers through Its C-terminal WH2 Domain by Mattila, Pieta K, Salminen, Marjo, Yamashiro, Takashi, Lappalainen, Pekka

“…The WH2 (WASP homology domain-2) is a small actin monomer-binding motif and is found in many proteins that regulate the actin cytoskeleton, including the…”
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The role of Tal2 and Tal1 in the differentiation of midbrain GABAergic neuron precursors by Achim, Kaia, Peltopuro, Paula, Lahti, Laura, Tsai, Hui-Hsin, Zachariah, Alyssa, Astrand, Mia, Salminen, Marjo, Rowitch, David, Partanen, Juha

“…Midbrain- and hindbrain-derived GABAergic interneurons are critical for regulation of sleep, respiratory, sensory-motor and motivational processes, and they…”
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Partially overlapping expression of Gata2 and Gata3 during inner ear development by Lilleväli, Kersti, Matilainen, Tanja, Karis, Alar, Salminen, Marjo

“…Gata2 and Gata3 belong to the Gata family of transcription factors in vertebrates that bind to a consensus “GATA” DNA sequence. The Gata3 gene is one of the…”
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Netrin 1 is required for semicircular canal formation in the mouse inner ear by Salminen, M, Meyer, B I, Bober, E, Gruss, P

“…The morphogenetic development of the mammalian inner ear is a complex multistep process, the molecular and cellular details of which are only beginning to be…”
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Mammals Have Two Twinfilin Isoforms Whose Subcellular Localizations and Tissue Distributions Are Differentially Regulated by Vartiainen, Maria K., Sarkkinen, Elisa M., Matilainen, Tanja, Salminen, Marjo, Lappalainen, Pekka

“…Twinfilin is a highly conserved actin monomer-binding protein that regulates cytoskeletal dynamics in organisms from yeast to mammals. In addition to the…”
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Analysis of Netrin 1 receptors during inner ear development by Matilainen, Tanja, Haugas, Maarja, Kreidberg, Jordan A, Salminen, Marjo

“…Netrin 1 plays key roles in axon guidance and neuronal migration during central nervous system (CNS) development. Outside the CNS, Netrin 1 has been shown to…”
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Apaf1-dependent programmed cell death is required for inner ear morphogenesis and growth by Cecconi, Francesco, Roth, Kevin A, Dolgov, Oleg, Munarriz, Eliana, Anokhin, Konstantin, Gruss, Peter, Salminen, Marjo

“…During inner ear development programmed cell death occurs in specific areas of the otic epithelium but the significance of it and the molecules involved have…”
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Defects in neural guidepost structures and failure to remove leptomeningeal cells from the septal midline behind the interhemispheric fusion defects in Netrin1 deficient mice by Hakanen, Janne, Salminen, Marjo

“…[Display omitted] •Midline glial structures are present in Ntn1 deficient mice.•Guidepost neurons are misplaced in Ntn1 deficient mice.•Nnt1 is expressed by…”
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Major reduction of rotavirus, but not norovirus, gastroenteritis in children seen in hospital after the introduction of RotaTeq vaccine into the National Immunization Programme in Finland by Hemming, Maria, Räsänen, Sirpa, Huhti, Leena, Paloniemi, Minna, Salminen, Marjo, Vesikari, Timo

“…Universal rotavirus (RV) vaccination is expected to reduce hospitalizations for acute gastroenteritis (GE) of children by eliminating most of severe RVGE, but…”
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