Search Results - "Salmen, Wilhelm"
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Broadly cross-reactive human antibodies that inhibit genogroup I and II noroviruses
Published in Nature communications (14-07-2021)“…The rational development of norovirus vaccine candidates requires a deep understanding of the antigenic diversity and mechanisms of neutralization of the…”
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Glycan recognition in globally dominant human rotaviruses
Published in Nature communications (06-07-2018)“…Rotaviruses (RVs) cause life-threatening diarrhea in infants and children worldwide. Recent biochemical and epidemiological studies underscore the importance…”
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3
Atomic structure of the predominant GII.4 human norovirus capsid reveals novel stability and plasticity
Published in Nature communications (10-03-2022)“…Human noroviruses (HuNoVs) cause sporadic and epidemic viral gastroenteritis worldwide. The GII.4 variants are responsible for most HuNoV infections, and GII.4…”
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Author Correction: Broadly cross-reactive human antibodies that inhibit genogroup I and II noroviruses
Published in Nature communications (14-10-2021)Get full text
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CLIC and membrane wound repair pathways enable pandemic norovirus entry and infection
Published in Nature communications (28-02-2023)“…Globally, most cases of gastroenteritis are caused by pandemic GII.4 human norovirus (HuNoV) strains with no approved therapies or vaccines available. The…”
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A single nanobody neutralizes multiple epochally evolving human noroviruses by modulating capsid plasticity
Published in Nature communications (16-10-2023)“…Acute gastroenteritis caused by human noroviruses (HuNoVs) is a significant global health and economic burden and is without licensed vaccines or antiviral…”
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Antiviral Activity of Olanexidine-Containing Hand Rub against Human Noroviruses
Published in mBio (26-04-2022)“…Human norovirus (HuNoV) is the leading cause of epidemic and sporadic acute gastroenteritis worldwide. HuNoV transmission occurs predominantly by direct…”
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Novel fold of rotavirus glycan-binding domain predicted by AlphaFold2 and determined by X-ray crystallography
Published in Communications biology (05-05-2022)“…The VP8* domain of spike protein VP4 in group A and C rotaviruses, which cause epidemic gastroenteritis in children, exhibits a conserved galectin-like fold…”
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Bile Goes Viral
Published in Viruses (27-05-2021)“…Laboratory cultivation of viruses is critical for determining requirements for viral replication, developing detection methods, identifying drug targets, and…”
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Positive and Negative Affinity Chromatography to Purify Norovirus P-Domain Protein
Published in Methods in molecular biology (Clifton, N.J.) (2022)“…Affinity chromatography enables the separation and isolation of proteins of interest from complex milieu of biochemicals. Nickel-charged affinity resins and…”
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Structural basis of glycan specificity in human rotaviruses
Published in Acta crystallographica. Section A, Foundations and advances (20-07-2018)“…Abstract only…”
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