Search Results - "Salman, Aydın"

Synthesis, antimycobacterial and antitumor activities of new (1,1-dioxido-3-oxo-1,2-benzisothiazol-2(3H)-yl)methyl N,N-disubstituted dithiocarbamate/O-alkyldithiocarbonate derivatives by Güzel, Özlen, Salman, Aydın

“…Reaction of 2-chloromethylsaccharin with substituted potassium dithiocarbamates and substituted potassium dithiocarbonates furnished…”
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Synthesis and biological evaluation of new 5-methyl-N-(3-oxo-1-thia-4-azaspiro[4.5]-dec-4-yl)-3-phenyl-1H-indole-2-carboxamide derivatives by Güzel, Özlen, Terzioğlu, Nalan, Çapan, Gültaze, Salman, Aydın

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N -(2,6-Dimethyl-3-oxo-1-thia-4-azaspiro[4.5]dec-4-yl)-2-hydroxy-2,2-diphenylacetamide by Yalçın, Şerife Pınar, Akkurt, Mehmet, Şahin, Ertan, Güzel, Özlen, Salman, Aydın, İhan, Eser

“…In the title compound, C24H28N2O3S, the pendant methyl C atom bonded to the cyclohexane ring is disordered over two sites in a 0.580 (11):0.420 (11) ratio. The…”
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Synthesis of new spiroindolinones incorporating a benzothiazole moiety as antioxidant agents by Karalı, Nilgün, Güzel, Özlen, Özsoy, Nurten, Özbey, Süheyla, Salman, Aydın

“…3 H-Spiro[1,3-benzothiazole-2,3′-indol]-2′(1′ H)-ones 3a– c and 4a– e were synthesized from treating the 5-substituted 1 H-indole-2,3-diones with…”
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Discovery of Low Nanomolar and Subnanomolar Inhibitors of the Mycobacterial β-Carbonic Anhydrases Rv1284 and Rv3273 by Güzel, Özlen, Maresca, Alfonso, Scozzafava, Andrea, Salman, Aydın, Balaban, Alexandru T, Supuran, Claudiu T

“…A series of 2-(hydrazinocarbonyl)-3-aryl-1H-indole-5-sulfonamides has been derivatized by reaction with 2,4,6-trimethylpyrylium perchlorate, leading to…”
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Carbonic anhydrase inhibitors. Aromatic/heterocyclic sulfonamides incorporating phenacetyl, pyridylacetyl and thienylacetyl tails act as potent inhibitors of human mitochondrial isoforms VA and VB by Güzel, Özlen, Innocenti, Alessio, Scozzafava, Andrea, Salman, Aydın, Supuran, Claudiu T.

“…K i (hCA I) = 263 nM, K i (hCA II) = 395 nM K i (hCA VA) = 7.1 nM, Ki (hCA VB) = 5.9 nM. A series of aromatic/heterocyclic sulfonamides incorporating…”
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Carbonic anhydrase inhibitors. Phenacetyl-, pyridylacetyl- and thienylacetyl-substituted aromatic sulfonamides act as potent and selective isoform VII inhibitors by Güzel, Özlen, Innocenti, Alessio, Scozzafava, Andrea, Salman, Aydın, Supuran, Claudiu T.

“…K i (hCA I) = 108 nM, K i (hCA II) = 107 nM K i (hCA VII) = 4.7 nM. A series of aromatic/heterocyclic sulfonamides incorporating phenyl(alkyl),…”
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Türkiye'de üretilen ilaç etken maddeleri: Prof. Dr. Nedime Ergenç, Prof. Dr. Serpil Salman, Doç. Dr. Aydın Salman by Ergenç, Nedime, Salman, Serpil, Salman, Aydın

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Synthesis and antituberculosis activity of 5-methyl/trifluoromethoxy-1 H-indole-2,3-dione 3-thiosemicarbazone derivatives by Güzel, Özlen, Karalı, Nilgün, Salman, Aydın

“…New series of 5-methyl/trifluoromethoxy-1 H-indole-2,3-dione 3-thiosemicarbazones 3a-t, 1-methyl-5-methyl/trifluoromethoxy-1 H-indole-2,3-dione…”
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Synthesis and biological evaluation of new 4-thiazolidinone derivatives by Güzel, Ozlen, Salman, Aydin

“…A series of new 2-aryl-4-thiazolidinones (3 and 4) was synthesized from 2-hydroxy-2,2-diphenyl-N'-[(substituted phenyl)methylene]acetohydrazides (2) and…”
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Carbonic anhydrase inhibitors. Synthesis of 2,4,6-trimethylpyridinium derivatives of 2-(hydrazinocarbonyl)-3-aryl-1H-indole-5-sulfonamides acting as potent inhibitors of the tumor-associated isoform IX and XII by Güzel, Özlen, Maresca, Alfonso, Scozzafava, Andrea, Salman, Aydın, Balaban, Alexandru T., Supuran, Claudiu T.

“…KI (hCA I)=7.6nM; KI (hCA II)=65nM, KI (hCA IX)=8.3nM; KI (hCA XII)=9.5nM. A series of 2-(hydrazinocarbonyl)-3-aryl-1H-indole-5-sulfonamides possessing various…”
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Carbonic anhydrase inhibitors: Synthesis and inhibition studies against mammalian isoforms I–XV with a series of 2-(hydrazinocarbonyl)-3-substituted-phenyl-1 H-indole-5-sulfonamides by Güzel, Özlen, Innocenti, Alessio, Scozzafava, Andrea, Salman, Aydın, Parkkila, Seppo, Hilvo, Mika, Supuran, Claudiu T.

“…A series of 2-(hydrazinocarbonyl)-3-substitutedphenyl-1 H-indole-5-sulfonamides possessing various 2-, 3- or 4- substituted phenyl groups with methyl-,…”
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Carbonic anhydrase inhibitors. Interaction of 2-(hydrazinocarbonyl)-3-phenyl-1 H-indole-5-sulfonamide with 12 mammalian isoforms: Kinetic and X-ray crystallographic studies by Güzel, Özlen, Temperini, Claudia, Innocenti, Alessio, Scozzafava, Andrea, Salman, Aydın, Supuran, Claudiu T.

“…2-(Hydrazinocarbonyl)-3-phenyl-1 H-indole-5-sulfonamide was tested for its interaction with 12 carbonic anhydrase (CA, EC 4.2.1.1) isoforms in the search of…”
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Crystal Structure of (1,1-Dioxido-3-oxo-1,2-benzisothiazol-2(3H)-yl)methyl O-propyl dithiocarbonate by AKKURT, Mehmet, YALÇIN, Serife Pinar, BÜYÜKGÜNGÖR, Orhan, GÜZEL, Özlen, SALMAN, Aydin

“…The title compound, C12H13NO4S3, crystalizes in the monoclinic P1 space group. The unit-cell parameters of the title compound are a = 6.7172(6), b = 8.7344(8),…”
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Synthesis and antituberculosis activity of 5-methyl/trifluoromethoxy-1H-indole-2,3-dione 3-thiosemicarbazone derivatives by Güzel, Ozlen, Karali, Nilgün, Salman, Aydin

“…New series of 5-methyl/trifluoromethoxy-1H-indole-2,3-dione 3-thiosemicarbazones 3a-t, 1-methyl-5-methyl/trifluoromethoxy-1H-indole-2,3-dione…”
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Crystal structure of 1,1,3-trioxo-2,3-dihydro-1,2-benzisothiazol-2-ylmethyl 4-phenyl piperazine-1-carbodithioate, C 19 H 19 N 3 O 3 S 3 by Akkurt, Mehmet, Yalçın, Şerife Pınar, Güzel, Özlen, Salman, Aydın, Büyükgüngör, Orhan

“…Abstract only…”
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Crystal structure of 1,1,3-trioxo-2,3-dihydro-1,2-benzisothiazol-2-ylmethyl 4-phenyl piperazine-1-carbodithioate, C 19 H 19 N 3 O 3 S 3 by Akkurt, Mehmet, Yalçın, Şerife Pınar, Güzel, Özlen, Salman, Aydın, Büyükgüngör, Orhan

“…Abstract only…”
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Carbonic anhydrase inhibitors. Interaction of 2-(hydrazinocarbonyl)-3-phenyl-1H-indole-5-sulfonamide with 12 mammalian isoforms : Kinetic and X-ray crystallographic studies by GÜZEL, Ozlen, TEMPERINI, Claudia, INNOCENTI, Alessio, SCOZZAFAVA, Andrea, SALMAN, Aydin, SUPURAN, Claudiu T

“…2-(Hydrazinocarbonyl)-3-phenyl-1H-indole-5-sulfonamide was tested for its interaction with 12 carbonic anhydrase (CA, EC 4.2.1.1) isoforms in the search of…”
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Synthesis and antituberculosis activity of 5-methyl/trifluoromethoxy-lH-indole-2,3-dione 3-thiosemicarbazone derivatives by GÜZEL, Ozlen, KARALI, Nilgün, SALMAN, Aydin

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Spectrophotometric determination of drugs having primary amine group with p-dimethylaminocinnamaldehyde by GÜZEL, Özlem, SALMAN, Aydın

“…İki farklı tablet preparatındaki dapson ve metoklopramid HCl'in tayini için yeni bir metod verilmektedir. Reaksiyonlar oda sıcaklığında sırasıyla 9 ve 20…”
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