Search Results - "Salles, Jerome"
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Chemokine Expression in Inflamed Adipose Tissue Is Mainly Mediated by NF-κB
Published in PloS one (18-06-2013)“…Immune cell infiltration of expanding adipose tissue during obesity and its role in insulin resistance has been described and involves chemokines. However,…”
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2
Skeletal Muscle Proteome Modifications following Antibiotic-Induced Microbial Disturbances in Cancer Cachexia
Published in Journal of proteome research (05-07-2024)“…Cancer cachexia is an involuntary loss of body weight, mostly of skeletal muscle. Previous research favors the existence of a microbiota-muscle crosstalk, so…”
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3
Obesity-associated Inflammation Induces microRNA-155 Expression in Adipocytes and Adipose Tissue: Outcome on Adipocyte Function
Published in The journal of clinical endocrinology and metabolism (01-04-2016)“…Context: Obesity alters adipose tissue's metabolic and endocrine functions and causes a chronic local and systemic low-grade inflammatory state to develop,…”
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4
Physiopathological Mechanism of Sarcopenia
Published in Clinics in geriatric medicine (01-08-2011)“…The etiology of sarcopenia is multifactorial but still poorly understood, and the sequelae of this phenomenon represent a major public health issue…”
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5
Citrulline directly modulates muscle protein synthesis via the PI3K/MAPK/4E-BP1 pathway in a malnourished state: evidence from in vivo, ex vivo, and in vitro studies
Published in American journal of physiology: endocrinology and metabolism (01-01-2017)“…Citrulline (CIT) is an endogenous amino acid produced by the intestine. Recent literature has consistently shown CIT to be an activator of muscle protein…”
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6
Atrophy-related ubiquitin ligases, atrogin-1 and MuRF1 are up-regulated in aged rat Tibialis Anterior muscle
Published in Mechanisms of ageing and development (01-10-2006)“…A phenotypic feature of aging is skeletal muscle wasting. It is characterized by a loss of muscle mass and strength. Age-related loss of muscle mass occurs…”
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7
Reduced adiponectin expression after high‐fat diet is associated with selective up‐regulation of ALDH1A1 and further retinoic acid receptor signaling in adipose tissue
Published in The FASEB journal (01-01-2017)“…Adiponectin is an adipocyte‐derived adipokine with potent antidiabetic, anti‐inflammatory, and antiatherogenic activity. Long‐term, high‐fat diet results in…”
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8
Circulating Amino Acid Concentration after the Consumption of Pea or Whey Proteins in Young and Older Adults Affects Protein Synthesis in C2C12 Myotubes
Published in Nutrients (27-08-2024)“…As older adults tend to reduce their intake of animal-source proteins, plant-source proteins may offer valuable resources for better protein intake. The aim of…”
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9
Muscle ectopic fat deposition contributes to anabolic resistance in obese sarcopenic old rats through eIF2α activation
Published in Aging cell (01-12-2014)“…Summary Obesity and aging are characterized by decreased insulin sensitivity (IS) and muscle protein synthesis. Intramuscular ceramide accumulation has been…”
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10
Fast-digestive protein supplement for ten days overcomes muscle anabolic resistance in healthy elderly men
Published in Clinical nutrition (Edinburgh, Scotland) (01-06-2016)“…Summary Background/objective Adequate protein intake is crucial to maintain muscle protein content in elderly subjects, but quality of dietary proteins should…”
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Inhibition of the endocannabinoid system reverses obese phenotype in aged mice and partly restores skeletal muscle function
Published in American journal of physiology: endocrinology and metabolism (01-02-2023)“…Sarcopenia, the age-related loss of skeletal muscle mass, is associated with lipid accumulation and anabolic resistance; phenomena also observed in obesity and…”
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Paclitaxel therapy potentiates cold hyperalgesia in streptozotocin-induced diabetic rats through enhanced mitochondrial reactive oxygen species production and TRPA1 sensitization
Published in Pain (Amsterdam) (01-03-2012)“…Paclitaxel potentiates cold hyperalgesia in streptozotocin-induced diabetic rats through the combination of paclitaxel-induced increase in mitochondrial…”
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Isocaloric Diets with Different Protein-Carbohydrate Ratios: The Effect on Sleep, Melatonin Secretion and Subsequent Nutritional Response in Healthy Young Men
Published in Nutrients (01-12-2022)“…This study aimed to determine the short-term effect of two isocaloric diets differing in the ratio of protein−carbohydrate on melatonin levels, sleep, and…”
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1,25(OH)2-vitamin D3 enhances the stimulating effect of leucine and insulin on protein synthesis rate through Akt/PKB and mTOR mediated pathways in murine C2C12 skeletal myotubes
Published in Molecular nutrition & food research (01-12-2013)“…Scope In recent years, there has been a growing body of evidence pointing to an effect of vitamin D on muscle mass and function. Our aim was to investigate the…”
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15
Pea Proteins Have Anabolic Effects Comparable to Milk Proteins on Whole Body Protein Retention and Muscle Protein Metabolism in Old Rats
Published in Nutrients (25-11-2021)“…Plant proteins are attracting rising interest due to their pro-health benefits and environmental sustainability. However, little is known about the nutritional…”
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Associating Inulin with a Pea Protein Improves Fast-Twitch Skeletal Muscle Mass and Muscle Mitochondrial Activities in Old Rats
Published in Nutrients (01-09-2023)“…Aging is associated with a decline in muscle mass and function, leading to increased risk for mobility limitations and frailty. Dietary interventions…”
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Sarcopenia in older mice is characterized by a decreased anabolic response to a protein meal
Published in Archives of gerontology and geriatrics (01-03-2017)“…Highlights • Compared to young mice (10 months), old mice (25 months) display significantly lower skeletal muscle mass, strength and function. • Together with…”
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Alterations of the endocannabinoid system and circulating and peripheral tissue levels of endocannabinoids in sarcopenic rats
Published in Journal of cachexia, sarcopenia and muscle (01-02-2022)“…Background Activation of the endocannabinoid system (ECS) is associated with the development of obesity and insulin resistance, and with perturbed skeletal…”
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Deleterious Effect of High-Fat Diet on Skeletal Muscle Performance Is Prevented by High-Protein Intake in Adult Rats but Not in Old Rats
Published in Frontiers in physiology (17-01-2022)“…The phenotype of sarcopenic obesity is frequently associated with impaired muscle strength and performance. Ectopic lipid deposition may interfere with muscle…”
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Nutritional evaluation of mixed wheat–faba bean pasta in growing rats: impact of protein source and drying temperature on protein digestibility and retention
Published in British journal of nutrition (14-03-2019)“…This study aimed to evaluate the nutritional value of pasta enriched with legume or wheat gluten proteins and dried at varying temperature. A total of four…”
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