Search Results - "Sallee, V L"

Preclinical efficacy of travoprost, a potent and selective FP prostaglandin receptor agonist by Hellberg, M R, Sallee, V L, McLaughlin, M A, Sharif, N A, Desantis, L, Dean, T R, Zinke, P W

“…Travoprost is the isopropyl ester prodrug of a high affinity, selective FP prostaglandin full receptor agonist. In contrast to travoprost acid's high affinity…”
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Determinants of fatty acid and alcohol monomer activities in mixed micellar solutions by Sallee, V L

“…The determinants of monomer activities of lipids dissolved in micellar bile salt solutions have been studied using polyethylene discs as the organic phase of a…”
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Permeation of long-chain fatty acids and alcohols in rat intestine by Sallee, V L

“…Uptake of long-chain fatty acids and alcohols from micellar bile salt solutions has been studied with everted sacs of rat jejunum. These unidirectional uptake…”
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Unstirred water layers and absorption across the intestinal mucosa by Dietschy, J M, Sallee, V L, Wilson, F A

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Determination of unidirectional uptake rates for lipids across the intestinal brush border by Sallee, V L, Wilson, F A, Dietschy, J M

“…An in vitro method is presented which measures valid, unidirectional uptake rates for lipids across the intestinal brush border. This method combines analysis…”
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Comparison of the effects of prostaglandins and their esters on blood-aqueous barrier integrity and intraocular pressure in rabbits by DeSantis, Jr, L L, Sallee, V L

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Extraction of corticosterone from cell homogenates and subcellular fractions of the rat adrenal cortex. III. ACTH-induced temporal subcellular redistributions of steroid precursors to corticosterone by Mathew, J, Sallee, V L, Curtis, J, Mrotek, J

“…Cholesterol, pregnenolone, progesterone, 11-deoxycorticosterone (11-DOC) and corticosterone were quantitated in subcellular fractions isolated from in vivo…”
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Fatty acid and alcohol partitioning with intestinal brush border and erythrocyte membranes by Sallee, V L

“…Relative partition coefficients of fatty acids and alcohols between aqueous buffers and biological membranes have been determined from the linear relationship…”
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Determinants of intestinal mucosal uptake of short- and medium-chain fatty acids and alcohols by Sallee, V L, Dietschy, J M

“…Uptake rates across the jejunal brush border have been measured for water-soluble fatty acids and alcohols and analyzed to determine the relative roles of the…”
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Apparent monomer activity of saturated fatty acids in micellar bile salt solutions measured by a polyethylene partitioning system by Sallee, Verney L.

“…Partitioning of saturated fatty acids between discs of polyethylene film and aqueous buffer has been characterized and subsequently used to measure monomer…”
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Effects of topically applied falintolol: a new beta-adrenergic antagonist for treatment of glaucoma by Himber, J, Sallee, V L, Andermann, G, Bouzoubaa, M, Leclerc, G, De Santis, L

“…Changes in intraocular pressure (IOP) following topical administration of falintolol (0.5%-0.25%), a new beta-blocking agent, were studied in conscious albino…”
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A simple, inexpensive method for the measurement of in vivo intestinal activity by Sallee, V L, Gaugl, J F

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Identification and Characterization of the Ocular Hypotensive Efficacy of Travoprost, a Potent and Selective FP Prostaglandin Receptor Agonist, and AL-6598, a DP Prostaglandin Receptor Agonist by Hellberg, Mark R., McLaughlin, Marsha A., Sharif, Naj A., DeSantis, Louis, Dean, Tom R., Kyba, Evan P., Bishop, John E., Klimko, Peter G., Zinke, Paul W., Selliah, Robert D., Barnes, George, DeFaller, Joseph, Kothe, Angela, Landry, Theresa, Sullivan, E.Kenneth, Andrew, Russell, Davis, Alberta A., Silver, Lewis, Bergamini, Michael V.W., Robertson, Stella, Weiner, Alan L., Sallee, Verney L.

“…The structure-activity studies that led to the identification of travoprost, a highly selective and potent FP prostaglandin analog, and AL-6598, a DP…”
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3-Oxa-15-cyclohexyl prostaglandin DP receptor agonists as topical antiglaucoma agents by Hellberg, Mark R., Conrow, Raymond E., Sharif, Najam A., McLaughlin, Marsha A., Bishop, John E., Crider, Julie Y., Dean, W.Dennis, DeWolf, Kevin A., Pierce, David R., Sallee, Verney L., Selliah, Robert D., Severns, Bryon S., Sproull, Steven J., Williams, Gary W., Zinke, Paul W., Klimko, Peter G.

“…A series of prostaglandin DP agonists containing a 3-oxa-15-cyclohexyl motif was synthesized and evaluated in several in vitro and in vivo biological assays…”
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Apparent monomer activity of saturated fatty acids im micellar bile salt solutions measured by a polyethylene partitioning system by Sallee, V L

“…Partitioning of saturated fatty acids between discs of polyethylene film and aqueous buffer has been characterized and subsequently used to measure monomer…”
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Unstirred Water Layers in Intestine: Rate Determinant of Fatty Acid Absorption from Micellar Solutions by Wilson, Frederick A., Sallee, Verney L., Dietschy, John M.

“…Bile acid and fatty acid uptake from micellar solutions by intestinal cells fails to reflect the incremental free energy changes expected for permeation that…”
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A Simple, Inexpensive Method for the Measurement of in vivo Intestinal Activity by Sallee, V. L, Gaugl, J. F

“…Describes a system that monitors intestinal motility in vivo which is very sensitive, minimally injurious to the tissue, and inexpensive. Used are two…”
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