Search Results - "Sallés, Joan"
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Isolation of Platelet-Derived Exosomes from Human Platelet-Rich Plasma: Biochemical and Morphological Characterization
Published in International journal of molecular sciences (05-03-2022)“…Platelet-Rich Plasma (PRP) is enriched in molecular messengers with restorative effects on altered tissue environments. Upon activation, platelets release a…”
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Tadalafil crosses the blood–brain barrier and reverses cognitive dysfunction in a mouse model of AD
Published in Neuropharmacology (01-01-2013)“…Previous studies have demonstrated that cognitive function can be restored in mouse models of Alzheimer's disease (AD) following administration of sildenafil,…”
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Tuning the properties of peptide imprinted nanoparticles for protein immunoprecipitation using magnetic streptavidin beads
Published in Mikrochimica acta (1966) (01-11-2024)“…Maximizing the binding properties of thermoresponsive molecularly imprinted nanoparticles (MIN) was aimed to explore their feasibility as antibody substitutes…”
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Subsynaptic Distribution, Lipid Raft Targeting and G Protein-Dependent Signalling of the Type 1 Cannabinoid Receptor in Synaptosomes from the Mouse Hippocampus and Frontal Cortex
Published in Molecules (Basel, Switzerland) (16-11-2021)“…Numerous studies have investigated the roles of the type 1 cannabinoid receptor (CB1) in glutamatergic and GABAergic neurons. Here, we used the…”
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Intermittent ethanol exposure during adolescence impairs cannabinoid type 1 receptor-dependent long-term depression and recognition memory in adult mice
Published in Neuropsychopharmacology (New York, N.Y.) (01-01-2020)“…Binge drinking is a significant problem in adolescent populations, and because of the reciprocal interactions between ethanol (EtOH) consumption and the…”
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Endocannabinoid 2-Arachidonoylglycerol Synthesis and Metabolism at Neuronal Nuclear Matrix Fractions Derived from Adult Rat Brain Cortex
Published in International journal of molecular sciences (01-02-2023)“…In this report, we describe the kinetics characteristics of the diacylglycerol lipase-α (DGLα) located at the nuclear matrix of nuclei derived from adult…”
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Solid-phase synthesis of imprinted nanoparticles as artificial antibodies against the C-terminus of the cannabinoid CB1 receptor: exploring a viable alternative for bioanalysis
Published in Mikrochimica acta (1966) (01-11-2021)“…The production of artificial anti-CB1 antibodies in nanoparticle format is described using the solid-phase imprinting approach. Instead of whole protein…”
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Fit-for-purpose based testing and validation of antibodies to amino- and carboxy-terminal domains of cannabinoid receptor 1
Published in Histochemistry and cell biology (01-11-2021)“…Specific and selective anti-CB 1 antibodies are among the most powerful research tools to unravel the complex biological processes mediated by the CB 1…”
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Allosteric modulation of 5-HT1A receptors by zinc: Binding studies
Published in Neuropharmacology (01-02-2009)“…5-HT1A receptors were studied via [3H]WAY-100635 and [3H]8-OH-DPAT binding to rat brain cortical membranes. We characterized the effect of zinc (Zn2+) on the…”
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Effects of Platelet-Rich Plasma on Cellular Populations of the Central Nervous System: The Influence of Donor Age
Published in International journal of molecular sciences (09-02-2021)“…Platelet-rich plasma (PRP) is a biologic therapy that promotes healing responses across multiple medical fields, including the central nervous system (CNS)…”
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Design and validation of recombinant protein standards for quantitative Western blot analysis of cannabinoid CB1 receptor density in cell membranes: an alternative to radioligand binding methods
Published in Microbial cell factories (15-09-2022)“…Abstract Background Replacement of radioligand binding assays with antibody-antigen interaction-based approaches for quantitative analysis of G protein-coupled…”
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Lack of the Transient Receptor Potential Vanilloid 1 Shifts Cannabinoid-Dependent Excitatory Synaptic Plasticity in the Dentate Gyrus of the Mouse Brain Hippocampus
Published in Frontiers in neuroanatomy (07-07-2021)“…The transient receptor potential vanilloid 1 (TRPV1) participates in synaptic functions in the brain. In the dentate gyrus, post-synaptic TRPV1 in the granule…”
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PLCβ1 by-passes early growth response -1 to induce the differentiation of neuronal cells
Published in Cell death discovery (24-05-2024)“…The Gα q /phospholipase C-β (PLCβ) signaling system mediates calcium responses to a variety of hormones and neurotransmitters. Recent studies suggest that…”
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Selective up-regulation of cannabinoid CB1 receptor coupling to Go-proteins in suicide victims with mood disorders
Published in Biochemical pharmacology (01-11-2018)“…[Display omitted] Brain endocannabinoid system is proposed to play a role in the pathogenesis of affective disorders. In the present study, we analyzed the…”
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The Absence of the Transient Receptor Potential Vanilloid 1 Directly Impacts on the Expression and Localization of the Endocannabinoid System in the Mouse Hippocampus
Published in Frontiers in neuroanatomy (22-02-2021)“…The transient receptor potential vanilloid 1 (TRPV1) is a non-selective ligand-gated cation channel involved in synaptic transmission, plasticity, and brain…”
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Up-regulation of CB1 cannabinoid receptors located at glutamatergic terminals in the medial prefrontal cortex of the obese Zucker rat
Published in Frontiers in neuroanatomy (18-10-2022)“…The present study describes a detailed neuroanatomical distribution map of the cannabinoid type 1 (CB 1 ) receptor, along with the biochemical characterization…”
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New Insights into Gene Delivery to Human Neuronal Precursor NT2 Cells: A Comparative Study between Lipoplexes, Nioplexes, and Polyplexes
Published in Molecular pharmaceutics (02-11-2015)“…The transfection of human NTera2/D1 teratocarcinoma-derived cell line (or NT2 cells) represents a promising strategy for the delivery of exogenous proteins or…”
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EBI2 regulates CXCL13‐mediated responses by heterodimerization with CXCR5
Published in The FASEB journal (01-12-2012)“…B‐cell movement into lymphoid follicles depends on the expression of the chemokine receptor CXCR5 and the recently reported Epstein‐Barr virus‐induced receptor…”
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Nuclear diacylglycerol lipase‐α in rat brain cortical neurons: evidence of 2‐arachidonoylglycerol production in concert with phospholipase C‐β activity
Published in Journal of neurochemistry (01-03-2015)“…In this report, we describe the localization of diacylglycerol lipase‐α (DAGLα) in nuclei from adult cortical neurons, as assessed by double‐immunofluorescence…”
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