Search Results - "Salker, Madhuri S."
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1
Uterine Selection of Human Embryos at Implantation
Published in Scientific reports (06-02-2014)“…Human embryos frequently harbor large-scale complex chromosomal errors that impede normal development. Affected embryos may fail to implant although many first…”
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Disordered IL-33/ST2 activation in decidualizing stromal cells prolongs uterine receptivity in women with recurrent pregnancy loss
Published in PloS one (27-12-2012)“…Decidualization renders the endometrium transiently receptive to an implanting blastocyst although the underlying mechanisms remain incompletely understood…”
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3
Up-regulation of FGF23 release by aldosterone
Published in Biochemical and biophysical research communications (05-02-2016)“…The fibroblast growth factor (FGF23) plasma level is high in cardiac and renal failure and is associated with poor clinical prognosis of these disorders. Both…”
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Overexpression of human alpha-Synuclein leads to dysregulated microbiome/metabolites with ageing in a rat model of Parkinson disease
Published in Molecular neurodegeneration (04-07-2023)“…Braak's hypothesis states that sporadic Parkinson's disease (PD) follows a specific progression of pathology from the peripheral to the central nervous system,…”
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Gut Bacterial Metabolite Urolithin A Decreases Actin Polymerization and Migration in Cancer Cells
Published in Molecular nutrition & food research (01-04-2020)“…Scope Urolithin A (UA) is a gut‐derived bacterial metabolite from ellagic acid found in pomegranates, berries, and nuts can downregulate cell proliferation and…”
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Enhanced Suicidal Erythrocyte Death Contributing to Anemia in the Elderly
Published in Cellular physiology and biochemistry (01-05-2015)“…Background/Aims: Anemia, a common condition in the elderly, could result from impaired formation and/or from accelerated loss of circulating erythrocytes. The…”
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Negative Effect of Ellagic Acid on Cytosolic pH Regulation and Glycolytic Flux in Human Endometrial Cancer Cells
Published in Cellular physiology and biochemistry (01-01-2017)“…Background/Aims: Key properties of tumor cells include enhanced glycolytic flux with excessive consumption of glucose and formation of lactate. As glycolysis…”
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8
Deregulation of the serum- and glucocorticoid-inducible kinase SGK1 in the endometrium causes reproductive failure
Published in Nature medicine (01-11-2011)“…Jan Brosens and his colleagues have found that deregulation of a single kinase—SGK1, a kinase involved in fluid balance—in two distinct cellular compartments…”
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Downregulation of endometrial mesenchymal marker SUSD2 causes cell senescence and cell death in endometrial carcinoma cells
Published in PloS one (25-08-2017)“…The cause of death among the majority of endometrial cancer patients involves migration of cancer cells within the peritoneal cavity and subsequent…”
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Rel Family Transcription Factor NFAT5 Upregulates COX2 via HIF-1α Activity in Ishikawa and HEC1a Cells
Published in International journal of molecular sciences (01-04-2024)“…Nuclear factor of activated T cells 5 (NFAT5) and cyclooxygenase 2 (COX2; ) both participate in diverse pathologies including cancer progression. However, the…”
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Gut Bacterial Metabolite Urolithin A (UA) Mitigates Ca2+ Entry in T Cells by Regulating miR-10a-5p
Published in Frontiers in immunology (31-07-2019)“…The gut microbiota influences several biological functions including immune responses. Inflammatory bowel disease is favorably influenced by consumption of…”
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LEFTY2/endometrial bleeding-associated factor up-regulates Na+ Coupled Glucose Transporter SGLT1 expression and Glycogen Accumulation in Endometrial Cancer Cells
Published in PloS one (01-04-2020)“…LEFTY2 (endometrial bleeding associated factor; EBAF or LEFTYA), a cytokine released shortly before menstrual bleeding, is a negative regulator of cell…”
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Placental growth factor mediates pathological uterine angiogenesis by activating the NFAT5-SGK1 signaling axis in the endometrium: implications for preeclampsia development
Published in Biological research (17-08-2024)“…After menstruation the uterine spiral arteries are repaired through angiogenesis. This process is tightly regulated by the paracrine communication between…”
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LEFTY2 Controls Migration of Human Endometrial Cancer Cells via Focal Adhesion Kinase Activity (FAK) and miRNA-200a
Published in Cellular physiology and biochemistry (01-01-2016)“…Background: LEFTY2, a suppressor of cell proliferation, tumor growth, regulator of stemness and embryonic differentiation, is a negative regulator of cancer…”
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DJ-1 (Park7) affects the gut microbiome, metabolites and the development of innate lymphoid cells (ILCs)
Published in Scientific reports (30-09-2020)“…The proper communication between gut and brain is pivotal for the maintenance of health and, dysregulation of the gut-brain axis can lead to several clinical…”
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LeftyA decreases Actin Polymerization and Stiffness in Human Endometrial Cancer Cells
Published in Scientific reports (11-07-2016)“…LeftyA, a cytokine regulating stemness and embryonic differentiation, down-regulates cell proliferation and migration. Cell proliferation and motility require…”
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Green Tea Polyphenol-Sensitive Calcium Signaling in Immune T Cell Function
Published in Frontiers in nutrition (Lausanne) (28-01-2021)“…Polyphenol compounds found in green tea have a great therapeutic potential to influence multiple human diseases including malignancy and inflammation. In this…”
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Alkaline Cytosolic pH and High Sodium Hydrogen Exchanger 1 (NHE1) Activity in Th9 Cells
Published in The Journal of biological chemistry (04-11-2016)“…CD4+ T helper 9 (Th9) cells are a newly discovered Th cell subset that produce the pleiotropic cytokine IL-9. Th9 cells can protect against tumors and provide…”
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Acid Sphingomyelinase (ASM) is a Negative Regulator of Regulatory T Cell (Treg) Development
Published in Cellular physiology and biochemistry (01-01-2016)“…Background/Aims: Regulatory T cell (Treg) is required for the maintenance of tolerance to various tissue antigens and to protect the host from autoimmune…”
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SGLT1 Deficiency Turns Listeria Infection into a Lethal Disease in Mice
Published in Cellular physiology and biochemistry (01-01-2017)“…Abstract Background: Cellular glucose uptake may involve either non-concentrative glucose carriers of the GLUT family or Na+-coupled glucose-carrier SGLT1,…”
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