Search Results - "Salinas, Edward"

Adapting OECD Aquatic Toxicity Tests for Use with Manufactured Nanomaterials: Key Issues and Consensus Recommendations by Petersen, Elijah J, Diamond, Stephen A, Kennedy, Alan J, Goss, Greg G, Ho, Kay, Lead, Jamie, Hanna, Shannon K, Hartmann, Nanna B, Hund-Rinke, Kerstin, Mader, Brian, Manier, Nicolas, Pandard, Pascal, Salinas, Edward R, Sayre, Phil

“…The unique or enhanced properties of manufactured nanomaterials (MNs) suggest that their use in nanoenabled products will continue to increase. This will…”
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Considerations of Environmentally Relevant Test Conditions for Improved Evaluation of Ecological Hazards of Engineered Nanomaterials by Holden, Patricia A, Gardea-Torresdey, Jorge L, Klaessig, Fred, Turco, Ronald F, Mortimer, Monika, Hund-Rinke, Kerstin, Cohen Hubal, Elaine A, Avery, David, Barceló, Damià, Behra, Renata, Cohen, Yoram, Deydier-Stephan, Laurence, Ferguson, P. Lee, Fernandes, Teresa F, Herr Harthorn, Barbara, Henderson, W. Matthew, Hoke, Robert A, Hristozov, Danail, Johnston, John M, Kane, Agnes B, Kapustka, Larry, Keller, Arturo A, Lenihan, Hunter S, Lovell, Wess, Murphy, Catherine J, Nisbet, Roger M, Petersen, Elijah J, Salinas, Edward R, Scheringer, Martin, Sharma, Monita, Speed, David E, Sultan, Yasir, Westerhoff, Paul, White, Jason C, Wiesner, Mark R, Wong, Eva M, Xing, Baoshan, Steele Horan, Meghan, Godwin, Hilary A, Nel, André E

“…Engineered nanomaterials (ENMs) are increasingly entering the environment with uncertain consequences including potential ecological effects. Various research…”
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Assessment of the bioaccumulation potential of four commonly used phenolic benzotriazoles based on in silico and experimental in vivo data by Leubner, Nadine, Pawlowski, Sascha, Salinas, Edward R., Wigh, Adriana, Dammann, Martina, Preibisch, Alina, Schmitt, Christian

“…Phenolic benzotriazoles (BTZs) are used globally as light stabilizers in various plastic products to protect them from photooxidative degradation. The same…”
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Are changes in vitellogenin concentrations in fish reliable indicators of chemical-induced endocrine activity? by Brown, Rebecca J., Panter, Grace H., Burden, Natalie, Salinas, Edward R., Weltje, Lennart, Wheeler, James R., Wolf, Yvonne, Lagadic, Laurent

“…Vitellogenin (VTG), a biomarker for endocrine activity, is a mechanistic component of the regulatory assessment of potential endocrine-disrupting properties of…”
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Endocrine disruption assessment in aquatic vertebrates – Identification of substance-induced thyroid-mediated effect patterns by Lagadic, Laurent, Coady, Katherine K., Körner, Oliver, Miller, Tara J., Mingo, Valentin, Salinas, Edward R., Sauer, Ursula G., Schopfer, Christel R., Weltje, Lennart, Wheeler, James R.

“…[Display omitted] •We propose a decision logic to identify thyroid disruption in aquatic vertebrates.•The decision logic is evidence-based and includes…”
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A Decision Logic for the Reliability Assessment and Interpretation of Vitellogenin Measurements by Brown, Rebecca J., Panter, Grace H., Burden, Natalie, Weltje, Lennart, Wheeler, James R., Salinas, Edward R., Wolf, Yvonne, Lagadic, Laurent

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Hormone data collection in support of endocrine disruption (ED) assessment for aquatic vertebrates: Pragmatic and animal welfare considerations by Wheeler, James R., Gao, Zhenglei, Lagadic, Laurent, Salinas, Edward R., Weltje, Lennart, Burden, Natalie

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Evaluation of the bioaccumulation of octocrylene after dietary and aqueous exposure by Pawlowski, Sascha, Lanzinger, Alexandra Christa, Dolich, Thomas, Füßl, Simone, Salinas, Edward R., Zok, Sabine, Weiss, Birgit, Hefner, Nicola, Van Sloun, Petra, Hombeck, Helena, Klingelmann, Eva, Petersen-Thiery, Mechtild

“…Octocrylene is used as UV filter in personal care products with a high production volume and can be detected in surface water and biota. It is liquid at…”
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Aquatic testing guidelines insufficiently control the influence of dilution water toc and hardness on cationic polymer toxicity – A proposal to improve standardized test procedures by Salinas, Edward R., Bozich, Jared S., Kolbenschlag, Sara, Kary-Heinrich, Miriam, Hopp, Philipp W., Lukas, Rüdiger, Zok, Sabine, Hidding, Björn

“…Cationic polymers (CPs) are widely used chemicals for wastewater treatment applications and in various “down-the-drain” household products. The aquatic…”
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An international cross-laboratory survey on fish vitellogenin analysis: Methodological challenges and opportunities for best practice by Burden, Natalie, Brown, Rebecca J., Holmes, Breanne, Panter, Grace H., Salinas, Edward R., Sewell, Fiona, Weltje, Lennart, Wheeler, James R., Wolf, Yvonne, Lagadic, Laurent

“…Vitellogenin (VTG) is a biomarker for possible endocrine activity of chemicals acting via the estrogen, androgen, or steroidogenesis pathways. VTG is assessed…”
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Intrinsic Xenobiotic Metabolizing Enzyme Activities in Early Life Stages of Zebrafish (Danio rerio) by Otte, Jens C, Schultz, Bernadette, Fruth, Daniela, Fabian, Eric, van Ravenzwaay, Bennard, Hidding, Björn, Salinas, Edward R

“…Early life stages of zebrafish (Danio rerio, zf) are gaining attention as an alternative invivo test system for drug discovery, early developmental toxicity…”
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Discovery of dysregulated circular RNAs in whole blood transcriptomes from cystic fibrosis patients – implication of a role for cellular senescence in cystic fibrosis by Salinas, Edward A., Macauley, Victor, Keeling, Kim M., Edwards, Yvonne J.K.

“…•This study highlights underexplored roles of circRNAs in cystic fibrosis (CF) with a perspective to provide a more complete molecular characterization of…”
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OECD validation study to assess intra- and inter-laboratory reproducibility of the zebrafish embryo toxicity test for acute aquatic toxicity testing by Busquet, François, Strecker, Ruben, Rawlings, Jane M., Belanger, Scott E., Braunbeck, Thomas, Carr, Gregory J., Cenijn, Peter, Fochtman, Przemyslaw, Gourmelon, Anne, Hübler, Nicole, Kleensang, André, Knöbel, Melanie, Kussatz, Carola, Legler, Juliette, Lillicrap, Adam, Martínez-Jerónimo, Fernando, Polleichtner, Christian, Rzodeczko, Helena, Salinas, Edward, Schneider, Katharina E., Scholz, Stefan, van den Brandhof, Evert-Jan, van der Ven, Leo T.M., Walter-Rohde, Susanne, Weigt, Stefan, Witters, Hilda, Halder, Marlies

“…•Zebrafish embryo acute toxicity test (ZFET) validated for aquatic toxicity testing.•20 chemicals tested in 11 laboratories with standardised ZFET…”
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Recommendations for Reducing the USE of Fish and Amphibians in Endocrine‐Disruption Testing of Biocides and Plant Protection Products in Europe by Lagadic, Laurent, Bender, Katrin, Burden, Natalie, Salinas, Edward R, Weltje, Lennart

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Aquatic toxicity tests with substances that are poorly soluble in water and consequences for environmental risk assessment by Weyman, Gabriel S., Rufli, Hans, Weltje, Lennart, Salinas, Edward R., Hamitou, Marc

“…Aquatic toxicity tests with substances that are poorly soluble in water have been conducted using different methods, and estimates of toxicity have varied…”
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MSPrecise: A molecular diagnostic test for multiple sclerosis using next generation sequencing by Rounds, William H., Salinas, Edward A., Wilks, Tom B., Levin, Mikhail K., Ligocki, Ann J., Ionete, Carolina, Pardo, Carlos A., Vernino, Steven, Greenberg, Benjamin M., Bigwood, Douglas W., Eastman, Eric M., Cowell, Lindsay G., Monson, Nancy L.

“…We have previously demonstrated that cerebrospinal fluid-derived B cells from early relapsing–remitting multiple sclerosis (RRMS) patients that express a VH4…”
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VDJML: a file format with tools for capturing the results of inferring immune receptor rearrangements by Toby, Inimary T, Levin, Mikhail K, Salinas, Edward A, Christley, Scott, Bhattacharya, Sanchita, Breden, Felix, Buntzman, Adam, Corrie, Brian, Fonner, John, Gupta, Namita T, Hershberg, Uri, Marthandan, Nishanth, Rosenfeld, Aaron, Rounds, William, Rubelt, Florian, Scarborough, Walter, Scott, Jamie K, Uduman, Mohamed, Vander Heiden, Jason A, Scheuermann, Richard H, Monson, Nancy, Kleinstein, Steven H, Cowell, Lindsay G

“…The genes that produce antibodies and the immune receptors expressed on lymphocytes are not germline encoded; rather, they are somatically generated in each…”
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Acute and chronic effects of nano- and non-nano-scale TiO2 and ZnO particles on mobility and reproduction of the freshwater invertebrate Daphnia magna by Wiench, Karin, Wohlleben, Wendel, Hisgen, Volker, Radke, Kristin, Salinas, Edward, Zok, Sabine, Landsiedel, Robert

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Cell-of-Origin Subtype Prediction of Diffuse Large B-Cell Lymphoma Using Gene Expression and Proteomic Data by Liu, Huiqing, Lu, Jin, Dong, Zhiwan, Liu, Hao, Salinas, Edward, Owens, Sherry, Pratta, Michael A., Smith, Michael F., Tada, Hiroomi, Newton, Robert C, Burn, Timothy

“…Introduction Diffuse large B-cell lymphoma (DLBCL) subtypes can be identified based on immunohistochemistry, somatic mutation and gene expression profiles…”
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A European perspective on alternatives to animal testing for environmental hazard identification and risk assessment by Scholz, Stefan, Sela, Erika, Blaha, Ludek, Braunbeck, Thomas, Galay-Burgos, Malyka, García-Franco, Mauricio, Guinea, Joaquin, Klüver, Nils, Schirmer, Kristin, Tanneberger, Katrin, Tobor-Kapłon, Marysia, Witters, Hilda, Belanger, Scott, Benfenati, Emilio, Creton, Stuart, Cronin, Mark T.D., Eggen, Rik I.L., Embry, Michelle, Ekman, Drew, Gourmelon, Anne, Halder, Marlies, Hardy, Barry, Hartung, Thomas, Hubesch, Bruno, Jungmann, Dirk, Lampi, Mark A., Lee, Lucy, Léonard, Marc, Küster, Eberhard, Lillicrap, Adam, Luckenbach, Till, Murk, Albertinka J., Navas, José M., Peijnenburg, Willie, Repetto, Guillermo, Salinas, Edward, Schüürmann, Gerrit, Spielmann, Horst, Tollefsen, Knut Erik, Walter-Rohde, Susanne, Whale, Graham, Wheeler, James R., Winter, Matthew J.

“…•Alternatives are yet only available for acute fish toxicity testing.•Limited access to animal test data hinders the development of alternatives.•Successful…”
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