Search Results - "Saliganan, Allen"

Detection of IL12/23p40 via PET Visualizes Inflammatory Bowel Disease by Rezazadeh, Farzaneh, Ramos, Nicholas, Saliganan, Allen-Dexter, Al-Hallak, Najeeb, Chen, Kang, Mohamad, Bashar, Wiesend, Wendy N, Viola, Nerissa T

“…Inflammatory bowel disease (IBD), which includes both Crohn disease and ulcerative colitis, is a relapsing inflammatory disease of the gastrointestinal tract…”
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p62/SQSTM1-induced caspase-8 aggresomes are essential for ionizing radiation-mediated apoptosis by Lee, Su Hyun, Cho, Won Jin, Najy, Abdo J., Saliganan, Allen-Dexter, Pham, Tri, Rakowski, Joseph, Loughery, Brian, Ji, Chang Hoon, Sakr, Wael, Kim, Seongho, Kato, Ikuko, Chung, Weon Kuu, Kim, Harold E., Kwon, Yong Tae, Kim, Hyeong-Reh C.

“…The autophagy–lysosome pathway and apoptosis constitute vital determinants of cell fate and engage in a complex interplay in both physiological and…”
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Evaluation and selection of a lead diabody for interferon-γ PET imaging by Rezazadeh, Farzaneh, Ramos, Nicholas, Saliganan, Allen-Dexter, Barr, Stephen, Peraino, Nicholas, Schomburg, Fritz, Rancour, David, Viola, Nerissa T.

“…Interferon-γ (IFN-γ) is an appealing target to evaluate immune response in cancer immunotherapy as it is a hallmark of an active immune system. Imaging and…”
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PTEN loss mediated Akt activation promotes prostate tumor growth and metastasis via CXCL12/CXCR4 signaling by Conley-LaComb, M Katie, Saliganan, Allen, Kandagatla, Pridvi, Chen, Yong Q, Cher, Michael L, Chinni, Sreenivasa R

“…The chemokine CXCL12, also known as SDF-1, and its receptor, CXCR4, are overexpressed in prostate cancers and in animal models of prostate-specific PTEN…”
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Discoidin Domain Receptors, DDR1b and DDR2, Promote Tumour Growth within Collagen but DDR1b Suppresses Experimental Lung Metastasis in HT1080 Xenografts by Wasinski, Benjamin, Sohail, Anjum, Bonfil, R. Daniel, Kim, Seongho, Saliganan, Allen, Polin, Lisa, Bouhamdan, Mohamad, Kim, Hyeong-Reh C., Prunotto, Marco, Fridman, Rafael

“…The Discoidin Domain Receptors (DDRs) constitute a unique set of receptor tyrosine kinases that signal in response to collagen. Using an inducible expression…”
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Platelet‐Derived Growth Factor‐D Overexpression Contributes to Epithelial‐Mesenchymal Transition of PC3 Prostate Cancer Cells by Kong, Dejuan, Wang, Zhiwei, Sarkar, Sarah H., Li, Yiwei, Banerjee, Sanjeev, Saliganan, Allen, Kim, Hyeong‐Reh Choi, Cher, Michael L., Sarkar, Fazlul H.

“…The majority of human malignancies are believed to have epithelial origin, and the progression of cancer is often associated with a transient process named…”
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Bone‐induced c‐kit expression in prostate cancer: A driver of intraosseous tumor growth by Mainetti, Leandro E., Zhe, Xiaoning, Diedrich, Jonathan, Saliganan, Allen D., Cho, Won Jin, Cher, Michael L., Heath, Elisabeth, Fridman, Rafael, Kim, Hyeong‐Reh Choi, Bonfil, R. Daniel

“…Loss of BRCA2 function stimulates prostate cancer (PCa) cell invasion and is associated with more aggressive and metastatic tumors in PCa patients…”
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In vitro and in vivo molecular evidence for better therapeutic efficacy of ABT-627 and taxotere combination in prostate cancer by BANERJEE, Sanjeev, HUSSAIN, Maha, ZHIWEI WANG, SALIGANAN, Allen, MINGXIN CHE, BONFIL, Daniel, CHER, Michael, SARKAR, Fazlul H

“…Bone is the key metastatic site for prostate cancer. Endothelin 1 (ET-1) produced abundantly by prostate cancer cells binds to its receptor present on bone…”
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Bone marrow stromal cells enhance prostate cancer cell invasion through type I collagen in an MMP‐12 dependent manner by Nabha, Sanaa M., dos Santos, Emanuel Burck, Yamamoto, Hamilto A., Belizi, Abdelfettah, Dong, Zhong, Meng, Hong, Saliganan, Allen, Sabbota, Aaron, Bonfil, R. Daniel, Cher, Michael L.

“…At the cellular level, the process of bone metastasis involves many steps. Circulating cancer cells enter the marrow, proliferate, induce neovascularization,…”
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Prostate Cancer Cell-Derived Urokinase-Type Plasminogen Activator Contributes to Intraosseous Tumor Growth and Bone Turnover by Dong, Zhong, Saliganan, Allen D., Meng, Hong, Nabha, Sanaa M., Sabbota, Aaron L., Sheng, Shijie, Bonfil, R. Daniel, Cher, Michael L.

“…A variety of proteases have been implicated in prostate cancer (PC) bone metastasis, but the individual contributions of these enzymes remain unclear…”
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The Inactive 44-kDa Processed Form of Membrane Type 1 Matrix Metalloproteinase (MT1-MMP) Enhances Proteolytic Activity via Regulation of Endocytosis of Active MT1-MMP by Cho, Jin-Ah, Osenkowski, Pamela, Zhao, Huiren, Kim, Seaho, Toth, Marta, Cole, Kristina, Aboukameel, Amro, Saliganan, Allen, Schuger, Lucia, Bonfil, R. Daniel, Fridman, Rafael

“…Membrane type 1 (MT1) matrix metalloproteinase (MMP-14) is a membrane-tethered MMP considered to be a major mediator of pericellular proteolysis. MT1-MMP is…”
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The mouse prostate: a basic anatomical and histological guideline by Oliveira, Daniel S M, Dzinic, Sijana, Bonfil, Alan I, Saliganan, Allen D, Sheng, Shijie, Bonfil, R Daniel

“…Despite substantial similarities in embryological, cellular and molecular biology features, human and mouse prostates differ in organ morphology and tissue…”
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Selective ablation of TRA-1-60 + pluripotent stem cells suppresses tumor growth of prostate cancer by White, Jordan M, Ramos, Nicholas, Saliganan, Allen-Dexter, Chung, Joon-Yong, Bell, Meghan, Lindquist, Jacob, Conner, Kayla, Wiesend, Wendy N, Schopperle, Michael, Patrick, Steve M, Kim, Seongho, Heath, Elisabeth I, Escorcia, Freddy E, Viola, Nerissa T

“…TRA-1-60 (TRA) is an established transcription factor of embryonic signaling and a well-known marker of pluripotency. It has been implicated in tumorigenesis…”
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Abstract 2135: Complex roles of discoidin domain receptors (DDRs) in tumor growth and experimental metastasis: role of collagen I in DDR-mediated tumor growth by Wasinski, Benjamin D., Bonfil, R. Daniel, Sohail, Anjum, Kim, Seong Ho, Polin, Lisa, Saliganan, Allen-Dexter, Bouhamdan, Mohamad, Nabi, Sayed, Kim, Hyeong-Reh C., Prunotto, Marco, Fridman, Rafael A.

“…Abstract DDR1 and DDR2 constitute a unique set of receptor tyrosine kinases that signal in response to collagen. Evidence indicates that DDRs play key roles in…”
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Abstract 1070: Discoidin domain receptor 1 (DDR1): A potential suppressor of prostate cancer progression by Bonfil, R. Daniel, Sohail, Anjum, Vranić, Semir, Oliveira, Daniel S., Shi, Dongping, Chen, Wei, Jang, Hyejeong, Saliganan, Allen D., Wasinski, Benjamin D., Kim, Hyeong-Reh C., Fridman, Rafael A.

“…Abstract Discoidin domain receptors DDR1 and DDR2 are the only receptor tyrosine kinases that bind to and signal in response to collagen. In cancer, DDRs have…”
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Bone-induced c-kit expression in prostate cancer: A driver of intraosseous tumor growth: Targeting c-kit inhibits intraosseous prostate tumors and upregulates BRCA2 by Mainetti, Leandro E., Zhe, Xiaoning, Diedrich, Jonathan, Saliganan, Allen D., Cho, Won Jin, Cher, Michael L., Heath, Elisabeth, Fridman, Rafael, Kim, Hyeong-Reh Choi, Bonfil, R. Daniel

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Abstract 4088: PTEN loss mediated Akt activation promotes prostate tumor growth via CXCL12/CXCR4 signaling by Conley-Lacomb, Katie, Saliganan, Allen, Chen, Yong Q., Kim, Hyeong-Reh C., Cher, Michael L., Chinni, Sreenivasa R.

“…Abstract Introduction: Chemokines are a family of cytokines known to regulate the migration of cells. The chemokine CXCL12, also known as SDF-1, and its…”
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Maspin expression in prostate tumor elicits host anti-tumor immunity by Dzinic, Sijana H, Chen, Kang, Thakur, Archana, Kaplun, Alexander, Bonfil, R Daniel, Li, Xiaohua, Liu, Jason, Bernardo, M Margarida, Saliganan, Allen, Back, Jessica B, Yano, Hiroshi, Schalk, Dana L, Tomaszewski, Elyse N, Beydoun, Ahmed S, Dyson, Gregory, Mujagic, Adelina, Krass, David, Dean, Ivory, Mi, Qing-Sheng, Heath, Elisabeth, Sakr, Wael, Lum, Lawrence G, Sheng, Shijie

“…The goal of the current study is to examine the biological effects of epithelial-specific tumor suppressor maspin on tumor host immune response. Accumulated…”
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Cediranib inhibits both the intraosseous growth of PDGF D-Positive prostate cancer cells and the associated bone reaction by Najy, Abdo J., Jung, Young Suk, Won, Joshua J., Conley-LaComb, M. Katie, Saliganan, Allen, Kim, Chong Jai, Heath, Elisabeth, Cher, Michael L., Bonfil, R. Daniel, Kim, Hyeong-Reh Choi

“…BACKGROUND The major cause of death in prostate cancer (PCa) cases is due to distant metastatic lesions, with the bone being the most prevalent site for…”
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Abstract B10: A novel mechanism of prostate cancer metastasis through the PDGF D/β-PDGFR axis by Najy, Abdo J., Saliganan, Allen, Bonfil, Daniel, Kim, Hyeong-Reh C.

“…Abstract Cancer metastasis is a multi-step process permitting malignant cells to invade into a secondary niche. Prostate cancer has a high prevalence of bone…”
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