Search Results - "Salie, Henrike"

SARS-CoV-2 vaccination can elicit a CD8 T-cell dominant hepatitis by Boettler, Tobias, Csernalabics, Benedikt, Salié, Henrike, Luxenburger, Hendrik, Wischer, Lara, Salimi Alizei, Elahe, Zoldan, Katharina, Krimmel, Laurenz, Bronsert, Peter, Schwabenland, Marius, Prinz, Marco, Mogler, Carolin, Neumann-Haefelin, Christoph, Thimme, Robert, Hofmann, Maike, Bengsch, Bertram

“…Autoimmune hepatitis episodes have been described following SARS-CoV-2 infection and vaccination but their pathophysiology remains unclear. Herein, we report…”
Get full text

Imaging mass cytometry for high-dimensional tissue profiling in the eye by Schlecht, Anja, Boneva, Stefaniya, Salie, Henrike, Killmer, Saskia, Wolf, Julian, Hajdu, Rozina Ida, Auw-Haedrich, Claudia, Agostini, Hansjürgen, Reinhard, Thomas, Schlunck, Günther, Bengsch, Bertram, Lange, Clemens AK

“…Background Imaging mass cytometry (IMC) combines the principles of flow cytometry and mass spectrometry (MS) with laser scanning spatial resolution and offers…”
Get full text

T-cell dysfunction in the glioblastoma microenvironment is mediated by myeloid cells releasing interleukin-10 by Ravi, Vidhya M., Neidert, Nicolas, Will, Paulina, Joseph, Kevin, Maier, Julian P., Kückelhaus, Jan, Vollmer, Lea, Goeldner, Jonathan M., Behringer, Simon P., Scherer, Florian, Boerries, Melanie, Follo, Marie, Weiss, Tobias, Delev, Daniel, Kernbach, Julius, Franco, Pamela, Schallner, Nils, Dierks, Christine, Carro, Maria Stella, Hofmann, Ulrich G., Fung, Christian, Sankowski, Roman, Prinz, Marco, Beck, Jürgen, Salié, Henrike, Bengsch, Bertram, Schnell, Oliver, Heiland, Dieter Henrik

“…Despite recent advances in cancer immunotherapy, certain tumor types, such as Glioblastomas, are highly resistant due to their tumor microenvironment disabling…”
Get full text

Deep spatial profiling of human COVID-19 brains reveals neuroinflammation with distinct microanatomical microglia-T-cell interactions by Schwabenland, Marius, Salié, Henrike, Tanevski, Jovan, Killmer, Saskia, Lago, Marilyn Salvat, Schlaak, Alexandra Emilia, Mayer, Lena, Matschke, Jakob, Püschel, Klaus, Fitzek, Antonia, Ondruschka, Benjamin, Mei, Henrik E., Boettler, Tobias, Neumann-Haefelin, Christoph, Hofmann, Maike, Breithaupt, Angele, Genc, Nafiye, Stadelmann, Christine, Saez-Rodriguez, Julio, Bronsert, Peter, Knobeloch, Klaus-Peter, Blank, Thomas, Thimme, Robert, Glatzel, Markus, Prinz, Marco, Bengsch, Bertram

“…COVID-19 can cause severe neurological symptoms, but the underlying pathophysiological mechanisms are unclear. Here, we interrogated the brain stems and…”
Get full text

Spatially resolved multi-omics deciphers bidirectional tumor-host interdependence in glioblastoma by Ravi, Vidhya M, Will, Paulina, Kueckelhaus, Jan, Sun, Na, Joseph, Kevin, Salié, Henrike, Vollmer, Lea, Kuliesiute, Ugne, von Ehr, Jasmin, Benotmane, Jasim K, Neidert, Nicolas, Follo, Marie, Scherer, Florian, Goeldner, Jonathan M, Behringer, Simon P, Franco, Pamela, Khiat, Mohammed, Zhang, Junyi, Hofmann, Ulrich G, Fung, Christian, Ricklefs, Franz L, Lamszus, Katrin, Boerries, Melanie, Ku, Manching, Beck, Jürgen, Sankowski, Roman, Schwabenland, Marius, Prinz, Marco, Schüller, Ulrich, Killmer, Saskia, Bengsch, Bertram, Walch, Axel K, Delev, Daniel, Schnell, Oliver, Heiland, Dieter Henrik

“…Glioblastomas are malignant tumors of the central nervous system hallmarked by subclonal diversity and dynamic adaptation amid developmental hierarchies. The…”
Get full text

T-cell exhaustion and residency dynamics inform clinical outcomes in hepatocellular carcinoma by Barsch, Maryam, Salié, Henrike, Schlaak, Alexandra Emilia, Zhang, Zhen, Hess, Moritz, Mayer, Lena Sophie, Tauber, Catrin, Otto-Mora, Patricia, Ohtani, Takuya, Nilsson, Tobias, Wischer, Lara, Winkler, Frances, Manne, Sasikant, Rech, Andrew, Schmitt-Graeff, Annette, Bronsert, Peter, Hofmann, Maike, Neumann-Haefelin, Christoph, Boettler, Tobias, Fichtner-Feigl, Stefan, van Boemmel, Florian, Berg, Thomas, Rimassa, Lorenza, Di Tommaso, Luca, Saeed, Anwaar, D’Alessio, Antonio, Pinato, David J., Bettinger, Dominik, Binder, Harald, John Wherry, E., Schultheiss, Michael, Thimme, Robert, Bengsch, Bertram

“…Despite recent translation of immunotherapies into clinical practice, the immunobiology of hepatocellular carcinoma (HCC), in particular the role and clinical…”
Get full text

In-Depth Molecular Characterization of Neovascular Membranes Suggests a Role for Hyalocyte-to-Myofibroblast Transdifferentiation in Proliferative Diabetic Retinopathy by Boneva, Stefaniya Konstantinova, Wolf, Julian, Hajdú, Rozina Ida, Prinz, Gabriele, Salié, Henrike, Schlecht, Anja, Killmer, Saskia, Laich, Yannik, Faatz, Henrik, Lommatzsch, Albrecht, Busch, Martin, Bucher, Felicitas, Stahl, Andreas, Böhringer, Daniel, Bengsch, Bertram, Schlunck, Günther, Agostini, Hansjürgen, Lange, Clemens A K

“…Retinal neovascularization (RNV) membranes can lead to a tractional retinal detachment, the primary reason for severe vision loss in end-stage disease…”
Get full text

Anti-PD-1 cancer immunotherapy induces central nervous system immune-related adverse events by microglia activation by Vinnakota, Janaki Manoja, Adams, Rachael C, Athanassopoulos, Dimitrios, Schmidt, Dominik, Biavasco, Francesca, Zähringer, Alexander, Erny, Daniel, Schwabenland, Marius, Langenbach, Marlene, Wenger, Valentin, Salié, Henrike, Cook, James, Mossad, Omar, Andrieux, Geoffroy, Dersch, Rick, Rauer, Sebastian, Duquesne, Sandra, Monaco, Gianni, Wolf, Phillipp, Blank, Thomas, Häne, Philipp, Greter, Melanie, Becher, Burkhard, Henneke, Philipp, Pfeifer, Dietmar, Blazar, Bruce R, Duyster, Justus, Boerries, Melanie, Köhler, Natalie, Chhatbar, Chintan M, Bengsch, Bertram, Prinz, Marco, Zeiser, Robert

“…Cancer treatment with anti-PD-1 immunotherapy can cause central nervous system immune-related adverse events (CNS-irAEs). The role of microglia in anti-PD-1…”
Get more information

The spatial distribution and detailed composition of infiltrating immune cells define autoimmune- and checkpoint-therapy associated hepatitis by Krimmel, Laurenz, Salie, Henrike, Killmer, Saskia, Lago, Marilyn Salvat, Rana, Nisha, Bronsert, Peter, Rafei-Shamsabadi, David, Meiss, Frank, Ehmer, Ursula, Krackhardt, Angela, Schwabenland, Marius, Prinz, Marco, Neumann-Haefelin, Christoph, Hofmann, Maike, Schultheiss, Michael, Thimme, Robert, Mogler, Carolin, Bengsch, Bertram

Get full text

Targeting TGFβ-activated kinase-1 activation in microglia reduces CAR T immune effector cell-associated neurotoxicity syndrome by Vinnakota, Janaki Manoja, Biavasco, Francesca, Schwabenland, Marius, Chhatbar, Chintan, Adams, Rachael C, Erny, Daniel, Duquesne, Sandra, El Khawanky, Nadia, Schmidt, Dominik, Fetsch, Viktor, Zähringer, Alexander, Salié, Henrike, Athanassopoulos, Dimitrios, Braun, Lukas M, Javorniczky, Nora R, Ho, Jenny N H G, Kierdorf, Katrin, Marks, Reinhard, Wäsch, Ralph, Simonetta, Federico, Andrieux, Geoffroy, Pfeifer, Dietmar, Monaco, Gianni, Capitini, Christian, Fry, Terry J, Blank, Thomas, Blazar, Bruce R, Wagner, Eva, Theobald, Matthias, Sommer, Clemens, Stelljes, Matthias, Reicherts, Christian, Jeibmann, Astrid, Schittenhelm, Jens, Monoranu, Camelia-Maria, Rosenwald, Andreas, Kortüm, Martin, Rasche, Leo, Einsele, Hermann, Meyer, Philipp T, Brumberg, Joachim, Völkl, Simon, Mackensen, Andreas, Coras, Roland, von Bergwelt-Baildon, Michael, Albert, Nathalie L, Bartos, Laura M, Brendel, Matthias, Holzgreve, Adrien, Mack, Matthias, Boerries, Melanie, Mackall, Crystal L, Duyster, Justus, Henneke, Philipp, Priller, Josef, Köhler, Natalie, Strübing, Felix, Bengsch, Bertram, Ruella, Marco, Subklewe, Marion, von Baumgarten, Louisa, Gill, Saar, Prinz, Marco, Zeiser, Robert

“…Cancer immunotherapy with chimeric antigen receptor (CAR) T cells can cause immune effector cell-associated neurotoxicity syndrome (ICANS). However, the…”
Get full text

OS-025-YI Spatial single-cell profiling and network analysis reveal the immune architecture of hepatocellular carcinoma associated with immune checkpoint inhibitor therapy outcome by Salié, Henrike, Wischer, Lara, Godbole, Ira, Otto-Mora, Patricia, Beck, Juergen, D'Alessio, Antonio, Neumann, Olaf, Stenzinger, Albrecht, Blaumeiser, Andreas, Boerries, Melanie, Hofmann, Maike, Thimme, Robert, Pinato, David J., Longerich, Thomas, Bengsch, Bertram

Get full text

Immune-Effector-Cell-Associated-Neurotoxicity-Syndrome (ICANS) Pathophysiology Is Mediated By Microglia TGF-β-Activated Kinase-1 Signaling by Vinnakota, Janaki Manoja, Biavasco, Francesca, Schwabenland, Marius, Chhatbar, Chintan, Adams, Rachael C, Erny, Daniel, Duquesne, Sandra, El Khawanky, Nadia, Salié, Henrike, Athanassopoulos, Dimitrios, Braun, Lukas, Schmidt, Dominik, Fetsch, Viktor, Javorniczky, Rebeka N., Ho, Jenny N.H.G, Marks, Reinhard, Wäsch, Ralph, Simonetta, Federico, Andrieux, Geoffroy, Pfeifer, Dietmar, Monaco, Gianni, Capitini, Christian, Fry, Terry J., Blank, Thomas, Blazar, Bruce R, Wagner Drouet, Eva-Maria, Theobald, Matthias, Sommer, Clemens, Stelljes, Matthias, Reicherts, Christian, Jeibmann, Astrid, Schittenhelm, Jens, Monoranu, Camelia-Maria, Rosenwald, Andreas, Kortüm, K. Martin, Rasche, Leo, Einsele, Hermann, Meyer, Philipp Tobias, Brumberg, Joachim, Mackensen, Andreas, von Bergwelt-Baildon, Michael, Coras, Roland, Albert, Nathalie L., Bartos, Laura M., Brendel, Matthias, Holzgreve, Adrien, Boerries, Melanie, Mackall, Crystal L., Duyster, Justus, Koehler, Natalie, Strübing, Felix, Bengsch, Bertram, Ruella, Marco, Subklewe, Marion, Baumgarten, Louisa von, Gill, Saar, Prinz, Marco, Zeiser, Robert

“…Chimeric antigen receptor (CAR)-T cell therapy has revolutionized the field of immune therapy in treating relapsed and refractory B cell malignancies. Despite…”
Get full text

Abstract 4539: Tumor evolution and immune microenvironment dynamics define response to neoadjuvant treatment of esophageal adenocarcinoma by Barroux, Melissa, Househam, Jacob, Lakatos, Eszter, Ronel, Tahel, Baker, Ann-Marie, Salié, Henrike, Mossner, Max, Smith, Kane, Kimberley, Chris, Nowinski, Salpie, Berner, Alison, Gunasri, Vinaya, Jansen, Marnix, Caravagna, Giulio, Slotta-Huspenina, Julia, Weichert, Wilko, Alberstmeier, Markus, Chain, Benny, Friess, Helmut, Bengsch, Bertram, Schmid, Roland M., Siveke, Jens T., Quante, Michael, Graham, Trevor A.

“…Introduction: Locally advanced esophageal adenocarcinoma (EAC) remains difficult to treat, and resistance is common. The ecological and evolutionary dynamics…”
Get full text