Search Results - "Saliba, Youakim"

VEGF‐C attenuates renal damage in salt‐sensitive hypertension by Beaini, Shadia, Saliba, Youakim, Hajal, Joelle, Smayra, Viviane, Bakhos, Jules‐Joel, Joubran, Najat, Chelala, Dania, Fares, Nassim

“…Salt‐sensitive hypertension is a major risk factor for renal impairment leading to chronic kidney disease. High‐salt diet leads to hypertonic skin interstitial…”
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Evidence of a Role for Fibroblast Transient Receptor Potential Canonical 3 Ca2+ Channel in Renal Fibrosis by Saliba, Youakim, Karam, Ralph, Smayra, Viviane, Aftimos, Georges, Abramowitz, Joel, Birnbaumer, Lutz, Farès, Nassim

“…Transient receptor potential canonical (TRPC) Ca(2+)-permeant channels, especially TRPC3, are increasingly implicated in cardiorenal diseases. We studied the…”
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Hypothyroidism and its rapid correction alter cardiac remodeling by Hajje, Georges, Saliba, Youakim, Itani, Tarek, Moubarak, Majed, Aftimos, Georges, Farès, Nassim

“…The cardiovascular effects of mild and overt thyroid disease include a vast array of pathological changes. As well, thyroid replacement therapy has been…”
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Circadian Rhythm Perturbation Aggravates Gut Microbiota Dysbiosis in Dextran Sulfate Sodium-Induced Colitis in Mice by Amara, Joseph, Itani, Tarek, Hajal, Joelle, Bakhos, Jules-Joel, Saliba, Youakim, Aboushanab, Saied A, Kovaleva, Elena G, Fares, Nassim, Mondragon, Alicia C, Miranda, Jose Manuel

“…Circadian rhythm disruption is increasingly considered an environmental risk factor for the development and exacerbation of inflammatory bowel disease. We have…”
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New insights in gut-liver axis in wild-type murine imiquimod-induced lupus by Maalouly, Georges, Hajal, Joelle, Noujeim, Charbel, Choueiry, Michel, Nassereddine, Hussein, Smayra, Viviane, Saliba, Youakim, Fares, Nassim

“…Background Intestinal and hepatic manifestations of lupus seem to be underestimated in comparison to other major organ lesions. Although recent data point to…”
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Critical Role for Stromal Interaction Molecule 1 in Cardiac Hypertrophy by HULOT, Jean-Sébastien, FAUCONNIER, Jeremy, HADRI, Lahouaria, JEONG, Dongtak, MÜHLSTEDT, Silke, SCHMITT, Joachim, BRAUN, Attila, BENARD, Ludovic, SALIBA, Youakim, LAGGERBAUER, Bernhard, NIESWANDT, Bernhard, LACAMPAGNE, Alain, RAMANUJAM, Deepak, HAJJAR, Roger J, LOMPRE, Anne-Marie, ENGELHARDT, Stefan, CHAANINE, Antoine, AUBART, Fleur, SASSI, Yassine, MERKLE, Sabine, CAZORLA, Olivier, OUILLE, Aude, DUPUIS, Morgan

“…Cardiomyocytes use Ca2+ not only in excitation-contraction coupling but also as a signaling molecule promoting, for example, cardiac hypertrophy. It is largely…”
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Blood Donation in Lebanon: A Six-Year Retrospective Study of a Decentralized Fragmented Blood Management System by Bakhos, Jules-Joel, Khalife, Myra, Teyrouz, Yorgui, Saliba, Youakim

“…Introduction In developing countries, the lack of a sufficient and safe blood supply is a significant impediment to providing health care. Lebanon is notable…”
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Antioxidant and Anti-Apoptotic Neuroprotective Effects of Cinnamon in Imiquimod-Induced Lupus by Maalouly, Georges, Martin, Christine-Marie-Anne, Baz, Yara, Saliba, Youakim, Baramili, Anna-Maria, Fares, Nassim

“…Despite accumulating evidence correlating oxidative stress with lupus disease activity, the brain redox pathways are still poorly investigated. Cinnamomum…”
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TRPC3 Regulates Islet Beta‐Cell Insulin Secretion by Rached, Gaëlle, Saliba, Youakim, Maddah, Dina, Hajal, Joelle, Smayra, Viviane, Bakhos, Jules‐Joel, Groschner, Klaus, Birnbaumer, Lutz, Fares, Nassim

“…Insulin release is tightly controlled by glucose‐stimulated calcium (GSCa) through hitherto equivocal pathways. This study investigates TRPC3, a non‐selective…”
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Mifepristone reduces hypothalamo-pituitary-adrenal axis activation and restores weight loss in rats subjected to dietary restriction and methylphenidate administration by Bou Khalil, Rami, Smayra, Viviane, Saliba, Youakim, Hajal, Joelle, Bakhos, Jules-Joël, Souaiby, Lama, Richa, Sami, Tamraz, Jean, Farès, Nassim

“…•Food restriction and methylphenidate administration can increase the activation of the hypothalamo-pituitary-adrenal axis.•Methylphenidate is responsible for…”
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Differential Gender-Dependent Patterns of Cardiac Fibrosis and Fibroblast Phenotypes in Aging Mice by Achkar, Angela, Fares, Nassim, Saliba, Youakim

“…Aging is characterized by physiological changes within the heart leading to fibrosis and dysfunction even in individuals without underlying pathologies. Gender…”
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Redox Imbalance and Mitogen-Activated Protein Kinase (MAPK) Activation Mediates Pneumoperitoneum-Induced Kidney Injury: FR-PO160 by Chalouhy, Charbel, Saliba, Youakim, Hajal, Joelle, Ajaimy, Maria, Fares, Nassim

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TRPC3, a Key Target in Cisplatin-Induced Renal Fibrosis: SA-PO124 by Najem, Hinda, Hajal, Joelle, Saliba, Youakim, Fares, Nassim

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PD17-03 REDOX IMBALANCE AND MAPK ACTIVATION MEDIATES PNEUMOPERITONEUM-INDUCED KIDNEY INJURY DURING MINIMALLY INVASIVE SURGERY by Chalouhy, Charbel, Fares, Nassim, Saliba, Youakim, Maria, Pedro, Aboumoouhamed, Ahmed, Kassis, Marwan, Small, Alexander, Loloi, Justin

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Hydrocortisone mitigates ICU-AW by fine-tuning of muscle atrophic and hypertrophic signaling pathways in a sepsis model with limb immobilization by Habr, Bassem, Saliba, Youakim, Hajal, Joelle, Smayra, Viviane, Riachy, Moussa, Fares, Nassim

“…Intensive care unit-acquired weakness (ICU-AW) is a complex spectrum of disability that delays recovery of critically ill-immobilized patients with sepsis…”
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Pirfenidone mitigates TGF-β1-mediated fibrosis in an idiopathic inflammatory myositis-associated interstitial lung disease model by Layoun, Habib, Hajal, Joelle, Saliba, Youakim, Smayra, Viviane, Habr, Bassem, Fares, Nassim

“…[Display omitted] Idiopathic inflammatory myositis (IIM) is a group of rare diseases of unknown etiology, with a pathognomonic muscular deficiency…”
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The Impact of Long‐Term Intake of Phenolic Compounds‐Rich Grape Pomace on Rat Gut Microbiota by Chacar, Stéphanie, Itani, Tarek, Hajal, Joelle, Saliba, Youakim, Louka, Nicolas, Faivre, Jean‐François, Maroun, Richard, Fares, Nassim

“…The aim of this work is to evaluate the impact on the rat microbiota of long‐term feeding with phenolic compounds (PC) rich grape pomace extracts. Thirty,…”
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Circadian Rhythm Disruption Aggravates DSS-Induced Colitis in Mice with Fecal Calprotectin as a Marker of Colitis Severity by Amara, Joseph, Saliba, Youakim, Hajal, Joelle, Smayra, Viviane, Bakhos, Jules-Joel, Sayegh, Raymond, Fares, Nassim

“…Background Inflammatory bowel disease (IBD) is a chronic immunologically mediated pathology that remains a major health burden. Circadian rhythm disruption…”
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Calcitriol Supplementation Protects Against Apoptosis and Alleviates the Severity of Abdominal Aortic Aneurysm Induced by Angiotensin II and Anti-TGFβ by Jreije, Afaf, Medlej-Hashim, Myrna, Hajal, Joelle, Saliba, Youakim, Chacar, Stephanie, Fares, Nassim, Khouzami, Lara

“…The present study aims to assess the effect of vitamin D deficiency (VDD) and its supplementation on the severity of AAA in mice. AAA was induced by AngII and…”
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Association between vitamin D deficiency and lipid and non-lipid markers of cardiovascular diseases in the middle east region by Nakhl, Sahar, Sleilaty, Ghassan, El Samad, Salam, Saliba, Youakim, Chahine, Ramez, Farès, Nassim

“…Background Previous studies have associated vitamin D deficiency with cardiovascular disease (CVD) markers. The underlying mechanism remains elusive. Lipid and…”
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