Search Results - "Sales, Maria E."
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1
Denatonium and Naringenin Promote SCA-9 Tumor Growth and Angiogenesis: Participation of Arginase
Published in Nutrition and cancer (04-07-2017)“…Submandibular gland (SMG) is one of the major salivary glands, and is formed by acinar cells that are conveyed to the oral cavity by a duct system. We had…”
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Topoisomerase Enzyme Inhibitors as Potential Drugs Against Cancer: What Makes Them Selective or Dual? - A Review
Published in Current pharmaceutical design (01-01-2022)“…Topoisomerase inhibitors are extensively used in cancer chemotherapy. In the process of identifying novel anticancer compounds, biological evaluations are…”
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3
A natural antiviral and immunomodulatory compound with antiangiogenic properties
Published in Microvascular research (01-11-2012)“…Meliacine (MA), an antiviral principle present in partially purified leaf extracts of Melia azedarach L., reduces viral load and abolishes the inflammatory…”
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4
The metronomic combination of paclitaxel with cholinergic agonists inhibits triple negative breast tumor progression. Participation of M2 receptor subtype
Published in PloS one (10-09-2020)“…Triple negative tumors are more aggressive than other breast cancer subtypes and there is a lack of specific therapeutic targets on them. Since muscarinic…”
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5
Angiogenesis signaling in breast cancer models is induced by hexachlorobenzene and chlorpyrifos, pesticide ligands of the aryl hydrocarbon receptor
Published in Toxicology and applied pharmacology (15-08-2020)“…Breast cancer incidence is increasing globally and pesticides exposure may impact risk of developing this disease. Hexachlorobenzene (HCB) and chlorpyrifos…”
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Overview of the New Bioactive Heterocycles as Targeting Topoisomerase Inhibitors Useful Against Colon Cancer
Published in Anti-cancer agents in medicinal chemistry (01-01-2024)“…Colorectal cancer (CRC) is the third most common cancer globally, with high mortality. Metastatic CRC is incurable in most cases, and multiple drug therapy can…”
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7
Macrophages derived from septic mice modulate nitric oxide synthase and angiogenic mediators in the heart
Published in Journal of cellular physiology (01-07-2013)“…Macrophages (Mps) can exert the defense against invading pathogens. During sepsis, bacterial lipopolisaccharide (LPS) activates the production of inflammatory…”
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8
Role of non-neuronal cholinergic system in breast cancer progression
Published in Life sciences (1973) (30-05-2007)“…We have previously reported the expression of functional muscarinic acetylcholine receptors (mAChR) in two different murine mammary adenocarcinoma cell lines…”
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9
Effect of bitter compounds on amylase secretion in murine submandibular glands: Signaling pathway mechanisms
Published in Biochimica et biophysica acta (01-12-2011)“…Amylase is synthesized in submandibular glands (SMG) and released into the oral cavity to degrade carbohydrates in the mouth. Bitter taste receptors (T2R)…”
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10
Immunoglobulin G from Breast Cancer Patients Regulates MCF-7 Cells Migration and MMP-9 Activity by Stimulating Muscarinic Acetylcholine Receptors
Published in Journal of clinical immunology (01-02-2013)“…Purpose We have previously reported the expression of muscarinic acetylcholine receptors (mAChR) in human breast tumors. The activation of these receptors…”
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11
Activation of muscarinic cholinergic receptors induces MCF-7 cells proliferation and angiogenesis by stimulating nitric oxide synthase activity
Published in Cancer biology & therapy (01-07-2007)“…Muscarinic acetylcholine receptors (mAChR) are members of the G-protein coupled receptor family. These receptors play key physiological roles and changes in…”
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12
Proliferative actions of muscarinic receptors expressed in macrophages derived from normal and tumor bearing mice
Published in Biochimica et biophysica acta (01-02-2008)“…Macrophages (Mps) are essential cellular components of the innate immune system. They are released from the bone marrow as immature monocytes and after…”
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13
Role of Muscarinic Acetylcholine Receptors in Breast Cancer: Design of Metronomic Chemotherapy
Published in Current clinical pharmacology (01-01-2019)“…muscarinic acetylcholine receptors (mAChRs) have attracted interest as targets for therapeutic interventions in different illnesses like Alzheimer´s disease,…”
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14
Muscarinic receptors participation in angiogenic response induced by macrophages from mammary adenocarcinoma-bearing mice
Published in Breast cancer research : BCR (01-01-2005)“…The role of macrophages in tumor progression has generated contradictory evidence. We had previously demonstrated the ability of peritoneal macrophages from…”
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15
The Power of Molecular Dynamics Simulations and Their Applications to Discover Cysteine Protease Inhibitors
Published in Mini reviews in medicinal chemistry (01-01-2024)“…A large family of enzymes with the function of hydrolyzing peptide bonds, called peptidases or cysteine proteases (CPs), are divided into three categories…”
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16
Bioprospecting of Nitrogenous Heterocyclic Scaffolds with Potential Action for Neglected Parasitosis: A Review
Published in Current pharmaceutical design (01-01-2020)“…Neglected parasitic diseases are a group of infections currently considered as a worldwide concern. This fact can be attributed to the migration of these…”
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17
The metronomic combination of paclitaxel with cholinergic agonists inhibits triple negative breast tumor progression. Participation of M.sub.2 receptor subtype
Published in PloS one (10-09-2020)“…Triple negative tumors are more aggressive than other breast cancer subtypes and there is a lack of specific therapeutic targets on them. Since muscarinic…”
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18
Reactivity of tumor-draining lymph nodes and the nitric oxide pathway
Published in International journal of oncology (01-01-2002)“…Regional lymph nodes are important in the generation of tumor-directed immune responses. The relationship between nitric oxide synthase (NOS) expression and…”
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19
Different muscarinc receptors are involved in the proliferation of murine mammary adenocarcinoma cell lines
Published in International journal of molecular medicine (01-02-2004)“…We described that two different murine mammary adenocarcinoma cell lines, LM3 and LM2 constitutively expressed muscarinic acetylcholine receptors (mAchR). We…”
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20
Educação feminina no Brasil: o que dizem as pesquisas publicadas no Portal da Capes (2015-2019)
Published in Práticas educativas, memórias e oralidades (Online) (01-05-2020)“…O objetivo deste estudo foi construir um inventário das produções científicas publicadas no Portal de Periódicos CAPES/MEC, referente à educação feminina no…”
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