Search Results - "Sales, Caroline B.S."
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1
Ru(II)-thymine complex causes DNA damage and apoptotic cell death in human colon carcinoma HCT116 cells mediated by JNK/p38/ERK1/2 via a p53-independent signaling
Published in Scientific reports (31-07-2019)“…Ru(II)-thymine complex [Ru(PPh 3 ) 2 (Thy)(bipy)]PF 6 (where PPh 3 = triphenylphosphine, Thy = thyminate and bipy = 2,2′-bipyridine) is a potent cytotoxic…”
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2
Ruthenium(II) complexes with 6-methyl-2-thiouracil selectively reduce cell proliferation, cause DNA double-strand break and trigger caspase-mediated apoptosis through JNK/p38 pathways in human acute promyelocytic leukemia cells
Published in Scientific reports (07-08-2019)“…Ruthenium(II) complexes with 6-methyl-2-thiouracil cis -[Ru(6m2tu) 2 (PPh 3 ) 2 ] ( 1 ) and [Ru(6m2tu) 2 (dppb)] ( 2 ) (where PPh 3 = triphenylphosphine; dppb…”
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3
In vitro and in vivo growth inhibition of human acute promyelocytic leukemia HL-60 cells by Guatteria megalophylla Diels (Annonaceae) leaf essential oil
Published in Biomedicine & pharmacotherapy (01-02-2020)“…Guatteria megalophylla Diels (Annonaceae) is an 8−10 m tall tree that grows near streams and is widely spread throughout Colombian, Ecuadorian, Peruvian,…”
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4
Essential oil from leaves of Conobea scoparioides (Cham. & Schltdl.) Benth. (Plantaginaceae) causes cell death in HepG2 cells and inhibits tumor development in a xenograft model
Published in Biomedicine & pharmacotherapy (01-09-2020)“…Conobea scoparioides (Cham. & Schltdl.) Benth. (syn. Sphaerotheca scoparioides Cham. & Schldtl.) (Plantaginaceae), popularly known as "pataqueira",…”
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5
MCM3: A Novel Proliferation Marker in Oral Squamous Cell Carcinoma
Published in Applied immunohistochemistry & molecular morphology (01-02-2018)“…The present study sought to evaluate and compare the immunoexpression of proteins minichromosome maintenance (MCM) 3 and Ki-67 in oral squamous cell carcinoma…”
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In vitro and in vivo anti-leukemia activity of the stem bark of Salacia impressifolia (Miers) A. C. Smith (Celastraceae)
Published in Journal of ethnopharmacology (01-03-2019)“…Salacia impressifolia (Miers) A. C. Smith (family Celastraceae) is a traditional medicinal plant found in the Amazon Rainforest known as “miraruíra”,…”
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Novel piplartine-containing ruthenium complexes: synthesis, cell growth inhibition, apoptosis induction and ROS production on HCT116 cells
Published in Oncotarget (28-11-2017)“…Piplartine (piperlongumine) is a plant-derived molecule that has been receiving intense interest due to its anticancer characteristics that target the…”
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Ruthenium Complexes With Piplartine Cause Apoptosis Through MAPK Signaling by a p53-Dependent Pathway in Human Colon Carcinoma Cells and Inhibit Tumor Development in a Xenograft Model
Published in Frontiers in oncology (03-07-2019)“…Ruthenium complexes with piplartine, [Ru(piplartine)(dppf)(bipy)](PF ) ( ) and [Ru(piplartine)(dppb)(bipy)](PF ) ( ) (dppf = 1,1-bis(diphenylphosphino)…”
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9
Ruthenium Complexes Containing Heterocyclic Thioamidates Trigger Caspase-Mediated Apoptosis Through MAPK Signaling in Human Hepatocellular Carcinoma Cells
Published in Frontiers in oncology (09-07-2019)“…Herein, ruthenium complexes containing heterocyclic thioamidates [Ru(mmi)(bipy)(dppb)]PF ( ), [Ru(tzdt)(bipy)(dppb)]PF ( ), [Ru(dmp)(bipy)(dppb)]PF ( ) and…”
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Evaluation of Mast Cell Density in the Tumor Microenvironment in Oral Epithelial Dysplasia and Oral Squamous Cell Carcinoma
Published in Applied immunohistochemistry & molecular morphology (01-11-2017)“…The objective of this study was to compare mast cell density (MCD) in oral epithelial dysplasias (OED) and oral squamous cell carcinoma (OSCC) and determine…”
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