Search Results - "Salerno, Costantino"

Metabolism of 4-hydroxy-2-nonenal in human polymorphonuclear leukocytes by Siems, Werner, Crifo, Carlo, Capuozzo, Elisabetta, Uchida, Koji, Grune, Tilman, Salerno, Costantino

“…► HNE degradation rate by human PMNL is very low, if compared with other cells. ► HNE degradation rate is even lower in the activated cells. ► GSH-HNE adduct…”
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Carotenoids and lung cancer: biochemical aspects by Salerno Costantino, Crifò Carlo, Siems Werner

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Diagnostic value of urinary orotic acid levels: applicable separation methods by Salerno, Costantino, Crifò, Carlo

“…Urinary orotic acid determination is a useful tool for screening hereditary orotic aciduria and for differentiating the hyperammonemia disorders which cannot…”
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Effects of the semisynthetic bis-indole derivative KAR-2 on store-operated calcium entry in human neutrophils by Salerno, Costantino, Capuozzo, Elisabetta

“…•Calcium traffic was studied in presence of Fura-2, as calcium probe, and KAR-2.•KAR-2 causes calcium release from the endoplasmic reticulum into the…”
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Scavenging properties of neutrophil 4-hydroxyphenylpyruvate dioxygenase are based on a hypothesis that does not stand up to scrutiny by Salerno, Costantino, Zicari, Alessandra, Mari, Emanuela, D’Eufemia, Patrizia

“…Abstract It was previously reported by D’Eufemia et al. [9] that neutrophil preparations from a patient with tyrosinemia type III, i.e. with inherited…”
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β-Carotene breakdown products may impair mitochondrial functions — potential side effects of high-dose β-carotene supplementation by Siems, Werner, Wiswedel, Ingrid, Salerno, Costantino, Crifò, Carlo, Augustin, Wolfgang, Schild, Lorenz, Langhans, Claus-Dieter, Sommerburg, Olaf

“…β-Carotene (BC) and other carotenoids are mainly considered as belonging to the group of micronutrients. As they are contained in fruit and vegetables and thus…”
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β-Carotene cleavage products after oxidation mediated by hypochlorous acid—a model for neutrophil-derived degradation by Sommerburg, Olaf, Langhans, Claus-Dieter, Arnhold, Jürgen, Leichsenring, Michael, Salerno, Costantino, Crifò, Carlo, Hoffmann, Georg F, Debatin, Klaus-Michael, Siems, Werner G

“…After β-carotene failed in certain clinical efficacy trials, there is evidence that the carotenoid might even be harmful, especially to smokers, when given in…”
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Neurologic aspects of adenylosuccinate lyase deficiency by Ciardo, F, Salerno, C, Curatolo, P

“…Adenylosuccinate lyase deficiency is an autosomal-recessive disorder of the purine de novo synthesis pathway, diagnosed up to now in approximately 40 patients…”
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Carotenoid cleavage products modify respiratory burst and induce apoptosis of human neutrophils by Siems, Werner, Capuozzo, Elisabetta, Crifò, Carlo, Sommerburg, Olaf, Langhans, Claus-Dieter, Schlipalius, Lance, Wiswedel, Ingrid, Kraemer, Klaus, Salerno, Costantino

“…Carotenoid supplementation in the treatment of diseases associated with oxidative stress has been recently questioned because of the cell damage and the…”
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Topical Review : Neurologic Aspects of Adenylosuccinate Lyase Deficiency by Ciardo, Francesca, Salerno, Costantino, Curatolo, Paolo

“…Adenylosuccinate lyase deficiency is an autosomal-recessive disorder of the purine de novo synthesis pathway, diagnosed up to now in approximately 40 patients…”
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Beta-carotene degradation products - formation, toxicity and prevention of toxicity by Siems, Werner, Salerno, Costantino, Crifò, Carlo, Sommerburg, Olaf, Wiswedel, Ingrid

“…Carotenoids are widely used as important micronutrients in food. Furthermore, carotenoid supplementation has been used in the treatment of diseases associated…”
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Failure of muscle energy metabolism in a patient with adenylosuccinate lyase deficiency: An in vivo study by phosphorus NMR spectroscopy by Salerno, Costantino, Iotti, Stefano, Lodi, Raffaele, Crifò, Carlo, Barbiroli, Bruno

“…31P-nuclear magnetic resonance spectroscopy was used to investigate in vivo the energy metabolism of the calf muscle in a 10-year-old patient with…”
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Misleading interpretations of coupled enzyme kinetics by Salerno, C

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Succinylpurinemic autism: increased sensitivity of defective adenylosuccinate lyase towards 4-hydroxy-2-nonenal by Salerno, Costantino, Siems, Werner G., Crifò, Carlo

“…We studied the effect of trans-4-hydroxy-2-nonenal on the wild-type human adenylosuccinate lyase and on the enzyme from a patient compound-heterozygous for two…”
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ATP-triggered calcium signals in human neutrophils by Crifo, C, Capuozzo, E, Ovadi, J, Salerno, C

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Identification of new mutations in the adenylosuccinate lyase gene associated with impaired enzyme activity in lymphocytes and red blood cells by Verginelli, Daniela, Luckow, Bruno, Crifò, Carlo, Salerno, Costantino, Gross, Manfred

“…We determined the DNA sequence of the adenylosuccinate lyase (ASL) gene from a 13 year-old female, who showed a reduced ASL enzymatic activity in lymphocytes…”
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Failure of muscle energy metabolism in a patient with adenylosuccinate lyase deficiency by Salerno, Costantino, Iotti, Stefano, Lodi, Raffaele, Crifò, Carlo, Barbiroli, Bruno

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Effects of calmodulin antagonists on calcium pump and cytosolic calcium level in human neutrophils by Capuozzo, Elisabetta, Verginelli, Daniela, Crifò, Carlo, Salerno, Costantino

“…The concentration of cytosolic free calcium was monitored in suspensions of intact human neutrophils in phosphate-buffered saline by means of the fluorescent…”
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Inhibition of NADPH oxidase-mediated superoxide radical formation in PMA-stimulated human neutrophils by 4-hydroxynonenal--binding to -SH and -NH2 groups by Siems, W G, Capuozzo, E, Verginelli, D, Salerno, C, Crifò, C, Grune, T

“…4-Hydroxynonenal (HNE), a major lipid peroxidation product, effectively inhibits the superoxide radical formation by NADPH oxidase of phorbol myristate acetate…”
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Microassay of Adenylosuccinase by Capillary Electrophoresis by Salerno, C., Crifo, C.

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