Search Results - "Salem, Heba F."

Nanosized Transferosome-Based Intranasal In Situ Gel for Brain Targeting of Resveratrol: Formulation, Optimization, In Vitro Evaluation, and In Vivo Pharmacokinetic Study by Salem, Heba F., Kharshoum, Rasha M., Abou-Taleb, Heba A., Naguib, Demiana M.

“…Resveratrol (RES) is a potent antioxidant used for the management of several central nervous system diseases. RES bioavailability is less than 1 owing to its…”
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Nanotransfersomes-loaded thermosensitive in situ gel as a rectal delivery system of tizanidine HCl: preparation, in vitro and in vivo performance by Moawad, Fatma A., Ali, Adel A., Salem, Heba F.

“…The purpose of the current study was to develop tizanidine HCl (TIZ; a myotonolytic agent used for treatment of spasticity) loaded nanotransfersomes intended…”
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Antitumor activity of intratracheal inhalation of temozolomide (TMZ) loaded into gold nanoparticles and/or liposomes against urethane-induced lung cancer in BALB/c mice by Hamzawy, Mohamed A., Abo-youssef, Amira M., Salem, Heba F., Mohammed, Sameh A.

“…The current study aimed to develop gold nanoparticles (GNPs) and liposome-embedded gold nanoparticles (LGNPs) as drug carriers for temozolomide (TMZ) and…”
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Enhancing the Bioavailability and Efficacy of Vismodegib for the Control of Skin Cancer: In Vitro and In Vivo Studies by Salem, Heba F, Gamal, Amr, Saeed, Haitham, Kamal, Marwa, Tulbah, Alaa S

“…Skin cancer is the most frequent cancer throughout the world. Vismodegib (VSD) is a hedgehog blocker approved for the prevention and treatment of skin cancer…”
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Sustained-release progesterone nanosuspension following intramuscular injection in ovariectomized rats by Salem, Heba F

“…The production of an intramuscular (IM) injection of natural progesterone would provide a safer solution than using semi synthetic progesterone. However,…”
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In Vitro and In Vivo Evaluation of the Effectiveness and Safety of Amygdalin as a Cancer Therapy by El-Ela, Fatma I. Abo, Gamal, Amr, Elbanna, Hossny Awad, ElBanna, Ahmed H, Salem, Heba F, Tulbah, Alaa S

“…Cancer is one of the most important causes of death worldwide. Several studies have shown the efficacy of apricot kernel seed as a cancer therapy due to the…”
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The Impact of Improving Dermal Permeation on the Efficacy and Targeting of Liposome Nanoparticles as a Potential Treatment for Breast Cancer by Salem, Heba F., Gamal, Amr, Saeed, Haitham, Tulbah, Alaa S.

“…Breast cancer is the most frequent malignancy in women. This work focuses on developing deformable liposomes as a potential carrier for breast cancer treatment…”
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A novel transdermal nanoethosomal gel of lercanidipine HCl for treatment of hypertension: optimization using Box-Benkhen design, in vitro and in vivo characterization by Salem, Heba F., El-Menshawe, Shahira F., Khallaf, Rasha A., Rabea, Yasmine K.

“…Poor bioavailability of drugs via oral route is the greatest challenge facing drug formulation. To overcome this obstacle, transdermal route was commonly used…”
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Improving the Antitumor Activity and Bioavailability of Sonidegib for the Treatment of Skin Cancer by Gamal, Amr, Saeed, Haitham, El-Ela, Fatma I. Abo, Salem, Heba F.

“…Throughout the United States and the world, skin cancer is the most frequent form of cancer. Sonidegib (SNG) is a hedgehog inhibitor that has been used for…”
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Fabrication and Appraisal of Simvastatin via Tailored Niosomal Nanovesicles for Transdermal Delivery Enhancement: In Vitro and In Vivo Assessment by Salem, Heba F, Kharshoum, Rasha M, Abou-Taleb, Heba A, Farouk, Hanan Osman, Zaki, Randa Mohammed

“…Simvastatin (SIM) is a HMG-CoA reductase inhibitor employed in the management of hyperlipidemia. However, its low bioavailability limits its clinical efficacy…”
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Exosomes-Mediated Transfer of Itga2 Promotes Migration and Invasion of Prostate Cancer Cells by Inducing Epithelial-Mesenchymal Transition by Gaballa, Rofaida, Ali, Hamdy E. A., Mahmoud, Mohamed O., Rhim, Johng S., Ali, Hamed I., Salem, Heba F., Saleem, Mohammad, Kandeil, Mohamed A., Ambs, Stefan, Abd Elmageed, Zakaria Y.

“…Although integrin alpha 2 subunit (ITGA2) mediates cancer progression and metastasis, its transfer by exosomes has not been investigated in prostate cancer…”
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Nano Methotrexate versus Methotrexate in Targeting Rheumatoid Arthritis by Salem, Heba F, Abd El-Maboud, Marwa Mohamed, Said, Amira S A, Salem, Mohamed Nabil, Sabry, Dina, Hussain, Nadia, El-Ghafar, Omnia A M Abd, Hussein, Raghda R S

“…Nanomedicine has emerged as an important approach for targeting RA medication. Rheumatoid arthritis (RA) is a widespread autoimmune disorder marked by multiple…”
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Development and Greenness Assessment of HPLC Method for Studying the Pharmacokinetics of Co-Administered Metformin and Papaya Extract by Abdelgawad, Mohamed A, Elmowafy, Mohammed, Musa, Arafa, Al-Sanea, Mohammad M, Nayl, AbdElAziz A, Ghoneim, Mohammed M, Ahmed, Yasmine M, Hassan, Hossam M, AboulMagd, Asmaa M, Salem, Heba F, Abdelwahab, Nada S

“…Foods with medical value have been proven to be beneficial, and they are extensively employed since they integrate two essential elements: food and medication…”
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The Outcomes and Adverse Drug Patterns of Immunomodulators and Thrombopoietin Receptor Agonists in Primary Immune Thrombocytopenia Egyptian Patients with Hemorrhage Comorbidity by Hamed, Eman Mostafa, Ibrahim, Ahmed R N, Meabed, Mohamed Hussein, Khalaf, Ahmed M, El Demerdash, Doaa Mohamed, Elgendy, Marwa O, Saeed, Haitham, Salem, Heba F, Rabea, Hoda

“…Immune thrombocytopenia (ITP) treatment has evolved recently. However, none of the treatments have only benefits without drawbacks. This study aimed to compare…”
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Predictors of methotrexate adherence and patient's awareness of it in rheumatoid arthritis and its effect on quality of life by Mohamed, Marwa, El-Maboud, Abd, Salem, Heba F, Salem, Mohamed N, Elmaaty, Mahmoud Abo, Eissa, Nermin, Said, Amira S A, Hussein, Raghda R S

“…Adherence studies among rheumatoid arthritis (RA) patients, in Egypt and throughout the Middle East region, are lacking. This study aimed to evaluate…”
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Therapeutic Outcomes of High Dose-Dexamethasone versus Prednisolone + Azathioprine, Rituximab, Eltrombopag, and Romiplostim Strategies in Persistent, Chronic, Refractory, and Relapsed Immune Thrombocytopenia Patients by Hamed, Eman Mostafa, Ibrahim, Ahmed R. N, Meabed, Mohamed Hussein, Khalaf, Ahmed M, El Demerdash, Doaa Mohamed, Elgendy, Marwa O, Saeed, Haitham, Salem, Heba F, Rabea, Hoda

“…Background: Primary immune thrombocytopenia (ITP) is an inflammatory autoimmune disease that can be managed with several treatment options. However, there is a…”
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Formulation and Therapeutic Evaluation of Isoxsuprine-Loaded Nanoparticles against Diabetes-Associated Stroke by Abou-Taleb, Heba A, Aldosari, Basmah Nasser, Zaki, Randa Mohammed, Afzal, Obaid, Tulbah, Alaa S, Shahataa, Mary Girgis, Abo El-Ela, Fatma I, Salem, Heba F, Fouad, Amr Gamal

“…Ischemic stroke is the second-leading cause of death. Hyperglycemia, which is characteristic of diabetes mellitus, contributes to the development of…”
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Continuous Versus Intermittent Linezolid Infusion for Critically Ill Patients with Hospital-Acquired and Ventilator-Associated Pneumonia: Efficacy and Safety Challenges by Abou Warda, Ahmed E, Sarhan, Rania M, Al-Fishawy, Hussein Saeed, Moharram, Ayman N, Salem, Heba F

“…High variability of linezolid blood concentrations with partial subtherapeutic levels was observed in critically ill patients who received a standard…”
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Correction: Empagliflozin versus Sitagliptin as add-on dual therapy in Egyptian patients with type 2 diabetes inadequately controlled with Metformin: a 12-week randomized, open-label, parallel-group trial by Zakaraia, Haitham G., Salem, Heba F., Mostafa, Mostafa A. A., Ali, Ahmed M., Rabea, Hoda M.

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Clinical Care Team’s Guide for Awareness on Risk Assessment of Eltrombopag Complicating Acute Kidney Injury in Relapsed Immune Thrombocytopenic Patients: A Case Report by Hamed, Eman Mostafa, Meabed, Mohamed Hussein, Ibrahim, Ahmed R. N, Khalaf, Ahmed M, El Demerdash, Doaa Mohamed, Elgendy, Marwa O, Saeed, Haitham, Mahmoud, Tamer M, Salem, Heba F, Rabea, Hoda

“…Immune thrombocytopenia (ITP) is an autoimmune bleeding disorder caused by antigen-specific T cells and antiplatelet autoantibodies that inhibit platelet…”
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