Search Results - "Saleh, Omar A."

Enzymatic degradation of liquid droplets of DNA is modulated near the phase boundary by Saleh, Omar A., Jeon, Byoung-jin, Liedl, Tim

“…Biomolecules can undergo liquid–liquid phase separation (LLPS), forming dense droplets that are increasingly understood to be important for cellular function…”
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Increasing valence pushes DNA nanostar networks to the isostatic point by Conrad, Nathaniel, Kennedy, Tynan, Fygenson, Deborah K., Saleh, Omar A.

“…The classic picture of soft material mechanics is that of rubber elasticity, in which material modulus is related to the entropic elasticity of flexible…”
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Vacuole dynamics and popping-based motility in liquid droplets of DNA by Saleh, Omar A., Wilken, Sam, Squires, Todd M., Liedl, Tim

“…Liquid droplets of biomolecules play key roles in organizing cellular behavior, and are also technologically relevant, yet physical studies of dynamic…”
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Tuning phase and aging of DNA hydrogels through molecular design by Nguyen, Dan T, Saleh, Omar A

“…The programmable, sequence-dependent hybridization of DNA has spurred the development of DNA hydrogels, polymer networks that swell in water and are comprised…”
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Tweezepy: A Python package for calibrating forces in single-molecule video-tracking experiments by Morgan, Ian L, Saleh, Omar A

“…Single-molecule force spectroscopy (SMFS) instruments (e.g., magnetic and optical tweezers) often use video tracking to measure the three-dimensional position…”
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Sequence-Dependent Elasticity and Electrostatics of Single-Stranded DNA: Signatures of Base-Stacking by McIntosh, Dustin B., Duggan, Gina, Gouil, Quentin, Saleh, Omar A.

“…Base-stacking is a key factor in the energetics that determines nucleic acid structure. We measure the tensile response of single-stranded DNA as a function of…”
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Active, motor-driven mechanics in a DNA gel by Bertrand, Olivier J. N., Fygenson, Deborah Kuchnir, Saleh, Omar A.

“…Cells are capable of a variety of dramatic stimuli-responsive mechanical behaviors. These capabilities are enabled by the pervading cytoskeletal network, an…”
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DNA unwinding by ring-shaped T4 helicase gp41 is hindered by tension on the occluded strand by Ribeck, Noah, Saleh, Omar A

“…The replicative helicase for bacteriophage T4 is gp41, which is a ring-shaped hexameric motor protein that achieves unwinding of dsDNA by translocating along…”
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Pattern of Uveitis in a Tertiary Hospital in North Jordan and the Impact of Behcet’s Disease by Alawneh, Khaldoon M., Saleh, Omar A., Smadi, Mahmoud M., Ababneh, Fatima Kamel, Ali Mahmoud, Ikhlas Hamed, Smadi, Areje M., Alawneh, Diala

“…Aim. The purpose of this study is to assess the prevalence of autoimmune-mediated uveitis in relation to other diseases and to describe the clinical patterns…”
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The Snakelike Chain Character of Unstructured RNA by Jacobson, David R., McIntosh, Dustin B., Saleh, Omar A.

“…In the absence of base-pairing and tertiary structure, ribonucleic acid (RNA) assumes a random-walk conformation, modulated by the electrostatic self-repulsion…”
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Direct Detection of Antibody-Antigen Binding Using an On-Chip Artificial Pore by Saleh, Omar A., Sohn, Lydia L.

“…We demonstrate a rapid and highly sensitive all-electronic technique based on the resistive pulse method of particle sizing with a pore to detect the binding…”
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Characteristics, fates and complications of long-term silicone oil tamponade after pars plana vitrectomy by Abu-Yaghi, Nakhleh E, Abu Gharbieh, Yazan A, Al-Amer, Ahmad M, AlRyalat, Saif Aldeen S, Nawaiseh, Mohammed B, Darweesh, Mohammad J, Alkukhun, Leen R, Abed, Alaa M, Saleh, Omar A, Ababneh, Osama H

“…Silicone oil tamponade has become a mainstay in treatment of advanced retinal detachment due to multiple etiologies. The aim of this study is to assess the…”
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Simulations of Stretching a Strong, Flexible Polyelectrolyte: Using Long Chains To Access the Pincus Scaling Regime by Stevens, Mark J, McIntosh, Dustin B, Saleh, Omar A

“…We present simulations of the stretching of a strongly charged, flexible polyelectrolyte chain for long chain lengths particularly focusing on the intermediate…”
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Nucleation dynamics of a model biomolecular liquid by Wilken, Sam, Gutierrez, Juan, Saleh, Omar A

“…Liquid-liquid phase separation in biology has recently been shown to play a major role in the spatial control of biomolecular components within the cell…”
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Bandpass Filtering of DNA Elastic Modes Using Confinement and Tension by Lin, Jun, Persson, Fredrik, Fritzsche, Joachim, Tegenfeldt, Jonas O., Saleh, Omar A.

“…During a variety of biological and technological processes, biopolymers are simultaneously subject to both confinement and external forces. Although…”
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Emulsion imaging of a DNA nanostar condensate phase diagram reveals valence and electrostatic effects by Conrad, Nathaniel, Chang, Grace, Fygenson, Deborah K, Saleh, Omar A

“…Liquid-liquid phase separation (LLPS) in macromolecular solutions (e.g., coacervation) is relevant both to technology and to the process of mesoscale structure…”
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International multi-center study of iatrogenic retinal tears in pars plana vitrectomy by Saleh, Omar A, Al-Dwairi, Rami A, Mohidat, Hasan, Jusufbegovic, Denis, Nesmith, Brooke, Barak, Yoreh, Mimouni, Michael, Schaal, Shlomit

“…To study and compare the effect of different surgical settings on the development of iatrogenic retinal tears (IRT) in conventional (20-gauge) and…”
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Sequence-Controlled Adhesion and Microemulsification in a Two-Phase System of DNA Liquid Droplets by Jeon, Byoung-jin, Nguyen, Dan T, Saleh, Omar A

“…Membrane-less organelles, the liquid droplets formed via liquid–liquid phase separation (LLPS) of biomolecules in cells, act to organize intracellular…”
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Glassy Dynamics and Memory Effects in an Intrinsically Disordered Protein Construct by Morgan, Ian L., Avinery, Ram, Rahamim, Gil, Beck, Roy, Saleh, Omar A.

“…Glassy, nonexponential relaxations in globular proteins are typically attributed to conformational behaviors that are missing from intrinsically disordered…”
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Magnetic tweezers characterization of the entropic elasticity of intrinsically disordered proteins and peptoids by Truong, Hoang P, Saleh, Omar A

“…Understanding the conformational behavior of biopolymers is essential to unlocking knowledge of their biophysical mechanisms and functional roles…”
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