Search Results - "Saleh, Mohammad I"
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Population Pharmacokinetics of Dasatinib in Healthy Subjects
Published in Pharmaceuticals (Basel, Switzerland) (23-05-2024)“…Dasatinib is one of the tyrosine kinase inhibitors. The main use of these agents is inhibition of cancerous cell proliferation. The therapeutic importance of…”
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A Bayesian Approach for Population Pharmacokinetic Modeling of Pegylated Interferon α-2a in Hepatitis C Patients
Published in Clinical pharmacokinetics (01-11-2017)“…Background Pegylated interferon α-2a (PEG-IFN-α-2a) is an antiviral drug used for the treatment of chronic hepatitis C virus (HCV) infection. This study…”
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3
Pharmacogenetic-guided Warfarin Dosing Algorithm in African-Americans
Published in Journal of cardiovascular pharmacology (01-01-2016)“…We aim to develop warfarin dosing algorithm for African-Americans. We explored demographic, clinical, and genetic data from a previously collected cohort of…”
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4
Clinical Predictors Associated With Warfarin Sensitivity
Published in American journal of therapeutics (01-11-2016)“…Our study aimed to identify predictors of warfarin sensitivity like demographic, clinical, and genetic data from a previously collected cohort of patients (n =…”
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5
Predictors of Severe Thrombocytopenia Secondary to Peginterferon Alfa-2a Treatment in Subjects With Hepatitis C Virus Infection
Published in American journal of therapeutics (01-11-2017)“…In this study, we aim to identify patient characteristics that predict severe thrombocytopenia induced by peginterferon alfa-2a in hepatitis C virus-infected…”
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6
Patient characteristics associated with peglyated interferon alfa‐2a induced neutropenia in chronic hepatitis C patients
Published in Clinical and experimental pharmacology & physiology (01-07-2018)“…Summary Neutropenia is a haematologic disorder commonly reported in patients with chronic hepatitis C virus (HCV) infection treated with pegylated interferon…”
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A population pharmacodynamic model characterizing neutropenia associated with pegylated interferon alpha 2-a therapy in patients with chronic hepatitis C viral infection
Published in Naunyn-Schmiedeberg's archives of pharmacology (01-09-2018)“…Neutropenia is a hematologic disorder commonly reported in patients with chronic hepatitis C viral (HCV) infection. The objective of the present analysis is to…”
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8
A time-to-event analysis describing virologic response in patients with chronic hepatitis C infection
Published in Journal of chemotherapy (Florence) (04-07-2019)“…The objective of this project was to describe longitudinal change in chronic hepatitis C virologic reponse using time-to-event (TTE) analysis and to identify…”
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9
Population Pharmacokinetics of Ibrutinib in Healthy Adults
Published in European journal of drug metabolism and pharmacokinetics (01-05-2021)“…Background and Objectives Ibrutinib is an antineoplastic agent that reduces B-cell proliferation by inhibiting Bruton's tyrosine kinase. We describes…”
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10
Dosage Individualization of Warfarin Using Artificial Neural Networks
Published in Molecular diagnosis & therapy (01-06-2014)“…Background and Objectives Our objective was to explore artificial neural networks (ANNs) as a possible tool for dosage individualization of warfarin. Methods…”
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11
Population Pharmacokinetics Modeling of Lamotrigine in Jordanian Epileptic Patients Using Dried Blood Spot Sampling
Published in Drug research (01-10-2021)“…To characterize the population pharmacokinetics of lamotrigine in Jordanian epileptic patients and to identify factors affecting therapeutic parameters. A…”
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12
Bayesian Population Pharmacokinetic Modeling of Eltrombopag in Chronic Hepatitis C Patients
Published in European journal of drug metabolism and pharmacokinetics (01-02-2019)“…Background and Objectives Eltrombopag is a thrombopoietic growth factor that is approved for the treatment of thrombocytopenia in chronic hepatitis C virus…”
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13
Evaluation of the impact of waterpipe tobacco smoke exposure on the activity and expression of rat hepatic CYP450: a pharmacokinetic study
Published in Inhalation toxicology (06-12-2018)“…Waterpipe smoke contains many toxic constituents that can alter drug pharmacokinetics. This study assessed the effect of waterpipe smoke exposure on the…”
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14
Population pharmacodynamic analysis of erythropoiesis in preterm infants for determining the anemia treatment potential of erythropoietin
Published in American journal of physiology. Regulatory, integrative and comparative physiology (01-05-2013)“…A population pharmacokinetics/pharmacodynamic (PK/PD) model was developed to describe changes in erythropoiesis as a function of plasma erythropoietin (EPO)…”
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15
Eltrombopag dose predictors in thrombocytopenic subjects with hepatitis C virus infection
Published in Clinical and experimental pharmacology & physiology (01-10-2015)“…Summary This study aims to identify patient characteristics that predict effective eltrombopag dosage for the treatment of Hepatitis C virus (HCV)‐related…”
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16
Pharmacodynamic analysis of stress erythropoiesis: change in erythropoietin receptor pool size following double phlebotomies in sheep
Published in Biopharmaceutics & drug disposition (01-04-2011)“…A feedback receptor regulation model was incorporated into a pharmacodynamic model to describe the stimulation of hemoglobin (Hb) production by endogenous…”
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Synthesis of Some More Fluorine Heterocyclic Nitrogen Systems Derived From Sulfa Drugs as Photochemical Probe Agents for Inhibition of Vitiligo Disease-Part I
Published in E-journal of chemistry (01-01-2011)“…Some more new bioactive fluorine heterocyclic systems containing sulfur and nitrogen as five-membered rings: pyrazoline, imidazole, imidazolopyrimidine,…”
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Synthesis of Fluorine Heterocyclic Nitrogen Systems Derived From Sulfa Drugs as PhotochemicalProbe Agents for Inhibition of Vitiligo Disease-Part II
Published in E-journal of chemistry (01-01-2010)“…Some more new bioactive fluorine heterocyclic systems containing sulfur and nitrogen as six-membered rings such as; N,Nʼ-disubstituted-thiobarbituric acid,…”
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Population pharmacokinetics of vancomycin in Jordanian patients
Published in Tropical journal of pharmaceutical research (01-02-2018)Get full text
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Carrier-mediated blends of Chitosan with polyvinyl chloride for different applications
Published in Journal of Saudi Chemical Society (01-04-2013)“…The current work aims at blending of PVC with Chitosan through simultaneous casting of their separate solutions in different proportions of PVC and Chitosan in…”
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