Search Results - "Saleh, Lana"

The Histological and Immunopathological Landscape of Lung Autopsy Sample of COVID 19 by Sardar Saleh, Lana

“…The purpose of this study is to explain the reason for the death histologically by comparing normal lungs with infected ones. The lung autopsy samples were…”
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Enzymatic methyl sequencing detects DNA methylation at single-base resolution from picograms of DNA by Vaisvila, Romualdas, Ponnaluri, V.K. Chaithanya, Sun, Zhiyi, Langhorst, Bradley W., Saleh, Lana, Guan, Shengxi, Dai, Nan, Campbell, Matthew A., Sexton, Brittany S., Marks, Katherine, Samaranayake, Mala, Samuelson, James C., Church, Heidi E., Tamanaha, Esta, Corrêa, Ivan R., Pradhan, Sriharsa, Dimalanta, Eileen T., Evans, Thomas C., Williams, Louise, Davis, Theodore B.

“…Bisulfite sequencing detects 5mC and 5hmC at single-base resolution. However, bisulfite treatment damages DNA, which results in fragmentation, DNA loss, and…”
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Nondestructive enzymatic deamination enables single-molecule long-read amplicon sequencing for the determination of 5-methylcytosine and 5-hydroxymethylcytosine at single-base resolution by Sun, Zhiyi, Vaisvila, Romualdas, Hussong, Laura-Madison, Yan, Bo, Baum, Chloé, Saleh, Lana, Samaranayake, Mala, Guan, Shengxi, Dai, Nan, Corrêa, Jr, Ivan R, Pradhan, Sriharsa, Davis, Theodore B, Evans, Jr, Thomas C, Ettwiller, Laurence M

“…The predominant methodology for DNA methylation analysis relies on the chemical deamination by sodium bisulfite of unmodified cytosine to uracil to permit the…”
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Virus-encoded glycosyltransferases hypermodify DNA with diverse glycans by Pyle, Jesse D., Lund, Sean R., O’Toole, Katherine H., Saleh, Lana

“…Enzymatic modification of DNA nucleobases can coordinate gene expression, nuclease protection, or mutagenesis. We recently discovered a clade of phage-specific…”
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A unilateral middle ear mass as an initial presentation of a probable IgG4-related disease: Case presentation by Saleh, Lana, Fayad, Jose, Aly, Mohammed Gamal

“…Over the past few years, multiple studies have shed light on the novel autoimmune inflammatory condition termed IgG4-related disorder (IgG4-RD). It…”
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Satisfaction and Quality of Life in Patients Who Underwent Post Massive Weight Loss Body Contouring Procedures: A Tertiary Center Experience in Bahrain by Shehab, Mohamed E., Isa, Hasan M., Saleh, Lana M., Alafeya, Zainab A.

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Tympanostomy Tube Insertion Versus Myringotomy or Observation in Managing Otitis Media With Effusion Following Radiotherapy for Nasopharyngeal Carcinoma: An Updated Review by Saleh, Lana M, Aly, Mohammed G, Alhedaithy, Alhanouf, AlAli, Saleh

“…Head and neck cancers, including nasopharyngeal carcinoma (NPC), are relatively common in Saudi Arabia. Radiotherapy is a standard treatment for NPC, but it…”
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Characteristics of Patients Admitted to the Burn and Plastic Surgery Unit: A Tertiary Center Experience in Bahrain by Shehab, Mohamed, M. Saleh, Lana, M. Isa, Hasan

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Biochemical characterization of a Naegleria TET-like oxygenase and its application in single molecule sequencing of 5-methylcytosine by Pais, June E., Dai, Nan, Tamanaha, Esta, Vaisvila, Romualdas, Fomenkov, Alexey I., Bitinaite, Jurate, Sun, Zhiyi, Guan, Shengxi, Corrêa, Ivan R., Noren, Christopher J., Cheng, Xiaodong, Roberts, Richard J., Zheng, Yu, Saleh, Lana

“…Modified DNA bases in mammalian genomes, such as 5-methylcytosine ((5m)C) and its oxidized forms, are implicated in important epigenetic regulation processes…”
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Protein splicing In Cis and In Trans by Saleh, Lana, Perler, Francine B.

“…Intein‐mediated protein splicing is a self‐catalytic process in which the intervening intein sequence is removed from a precursor protein and the flanking…”
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Nonlinear refractive and optical limiting measurements of 2-thienylchalcone derivatives under cw laser regime by Saleh, Lana M., Hassan, Hiba Abu, Henari, Fryad Z., Patil, P. S., Bannur, M. S.

“…The nonlinear refractive index of 2-thienylchalcone derivatives in solution was investigated using z -scan technique with a continuous wave Argon ion laser…”
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RimO, a MiaB-like enzyme, methylthiolates the universally conserved Asp88 residue of ribosomal protein S12 in Escherichia coli by Anton, Brian P, Saleh, Lana, Benner, Jack S, Raleigh, Elisabeth A, Kasif, Simon, Roberts, Richard J

“…Ribosomal protein S12 undergoes a unique posttranslational modification, methylthiolation of residue D88, in Escherichia coli and several other bacteria. Using…”
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Characterization of RimO, a New Member of the Methylthiotransferase Subclass of the Radical SAM Superfamily by Lee, Kyung-Hoon, Saleh, Lana, Anton, Brian P, Madinger, Catherine L, Benner, Jack S, Iwig, David F, Roberts, Richard J, Krebs, Carsten, Booker, Squire J

“…RimO, encoded by the yliG gene in Escherichia coli, has been recently identified in vivo as the enzyme responsible for the attachment of a methylthio group on…”
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Nature of the Peroxo Intermediate of the W48F/D84E Ribonucleotide Reductase Variant:  Implications for O2 Activation by Binuclear Non-Heme Iron Enzymes by Skulan, Andrew J, Brunold, Thomas C, Baldwin, Jeffrey, Saleh, Lana, Bollinger, J. Martin, Solomon, Edward I

“…Analysis of the spectroscopic signatures of the R2-W48F/D84E biferric peroxo intermediate identifies a cis μ-1,2 peroxo coordination geometry. DFT geometry…”
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Electronic and Spectroscopic Studies of the Non-Heme Reduced Binuclear Iron Sites of Two Ribonucleotide Reductase Variants:  Comparison to Reduced Methane Monooxygenase and Contributions to O2 Reactivity by Wei, Pin-pin, Skulan, Andrew J, Mitić, Natasa, Yang, Yi-Shan, Saleh, Lana, Bollinger, J. Martin, Solomon, Edward I

“…Circular dichroism (CD), magnetic circular dichroism (MCD), and variable-temperature variable-field (VTVH) MCD have been used to probe the biferrous active…”
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Variable Coordination Geometries at the Diiron(II) Active Site of Ribonucleotide Reductase R2 by Voegtli, Walter C, Sommerhalter, Monika, Saleh, Lana, Baldwin, Jeffrey, Bollinger, J. Martin, Rosenzweig, Amy C

“…The R2 subunit of Escherichia coli ribonucleotide reductase contains a dinuclear iron center that generates a catalytically essential stable tyrosyl radical by…”
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Use of a Chemical Trigger for Electron Transfer to Characterize a Precursor to Cluster X in Assembly of the Iron-Radical Cofactor of Escherichia coli Ribonucleotide Reductase by Saleh, Lana, Krebs, Carsten, Ley, Brenda A, Naik, Sunail, Huynh, Boi Hanh, Bollinger, J. Martin

“…A key step in generation of the catalytically essential tyrosyl radical (Y122•) in protein R2 of Escherichia coli ribonucleotide reductase is electron transfer…”
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What are the advantages/disadvantages of postdoctoral training in industry? by Saleh, Lana

“…Abstract only Biotech and pharmaceutical companies recruit postdoctoral researchers to perform cutting‐edge research beyond the scope of the designated…”
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Detection of TET-Oxidized 5-Methylcytosine Bases by Capillary Gel Electrophoresis by Vaisvila, Romualdas, Hunault, Lise, Saleh, Lana

“…The oxidation activity of the mammalian ten-eleven translocation dioxygenase (TET) on 5-methylcytosine (5mC) of DNA is usually monitored by analytical methods…”
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Distributive Processing by the Iron(II)/α-Ketoglutarate-Dependent Catalytic Domains of the TET Enzymes Is Consistent with Epigenetic Roles for Oxidized 5‑Methylcytosine Bases by Tamanaha, Esta, Guan, Shengxi, Marks, Katherine, Saleh, Lana

“…The ten-eleven translocation (TET) proteins catalyze oxidation of 5-methylcytosine (5mC) residues in nucleic acids to 5-hydroxymethylcytosine (5hmC),…”
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