Search Results - "Saleh, Aya M."
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Non-canonical amino acid labeling in proteomics and biotechnology
Published in Journal of biological engineering (22-05-2019)“…Metabolic labeling of proteins with non-canonical amino acids (ncAAs) provides unique bioorthogonal chemical groups during de novo synthesis by taking…”
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Extracellular matrix protein composition dynamically changes during murine forelimb development
Published in iScience (16-02-2024)“…The extracellular matrix (ECM) is an integral part of multicellular organisms, connecting different cell layers and tissue types. During morphogenesis and…”
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Metabolic labeling of secreted matrix to investigate cell–material interactions in tissue engineering and mechanobiology
Published in Nature protocols (01-03-2022)“…Re-creating features of the native extracellular matrix (ECM) with engineered biomaterials has become a valuable tool to probe the influence of ECM properties…”
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The Dynamic Relationship of Breast Cancer Cells and Fibroblasts in Fibronectin Accumulation at Primary and Metastatic Tumor Sites
Published in Cancers (17-05-2020)“…In breast cancer (BC), tissue stiffening via fibronectin (FN) and collagen accumulation is associated with advanced disease progression at both the primary…”
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Fluorescent Probes for Monitoring Serine Ubiquitination
Published in Biochemistry (Easton) (07-04-2020)“…In a radical departure from the classical E1–E2–E3 three-enzyme mediated ubiquitination of eukaryotes, the recently described bacterial enzymes of the SidE…”
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Dynamics of Non-Canonical Amino Acid-Labeled Intra- and Extracellular Proteins in the Developing Mouse
Published in Cellular and molecular bioengineering (01-10-2019)“…Introduction Mapping protein synthesis and turnover during development will provide insight into functional tissue assembly; however, quantitative in vivo…”
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An Integrative Biology Approach to Quantify the Biodistribution of Azidohomoalanine In Vivo
Published in Cellular and molecular bioengineering (01-04-2023)“…Background Identification and quantitation of newly synthesized proteins (NSPs) are critical to understanding protein dynamics in development and disease…”
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