Search Results - "Saleemuddin, M"

Augmenting the cytotoxicity of oleic acid-protein complexes: Potential of target-specific antibodies by Hoque, Mehboob, Gupta, Jyoti, Saleemuddin, M.

“…HAMLET (Human Alpha-Lactalbumin Made LEthal to Tumor cells), a complex of oleic acid (OA) with partially unfolded human α-lactalbumin, shows remarkable…”
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Acid pH promotes bispecific antibody formation by the redox procedure by Gupta, Jyoti, Hoque, Mehboob, Ahmad, Md Fahim, Khan, Rizwan Hasan, Saleemuddin, M.

“…Bispecific antibodies (BsAbs), are potential theranostics. Chemical procedures of preparation of BsAbs, in which two monospecific antibodies are split into…”
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Oleic acid complex of bovine α-lactalbumin induces eryptosis in human and other erythrocytes by a Ca(2+)-independent mechanism by Hoque, Mehboob, Nanduri, Ravikanth, Gupta, Jyoti, Mahajan, Sahil, Gupta, Pawan, Saleemuddin, M

“…Complexes of oleic acid (OA) with milk α-lactalbumin, received remarkable attention in view of their selective toxicity towards a spectrum of tumors during the…”
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A detergent-based procedure for the preparation of IgG-like bispecific antibodies in high yield by Gupta, Jyoti, Hoque, Mehboob, Zaman, Masihuz, Khan, Rizwan Hasan, Saleemuddin, M.

“…Bispecific antibodies (BsAbs), with the ability to recognize two different epitopes simultaneously, offer remarkable advantages in bioassays, cancer therapy,…”
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Behaviour of oleic acid-depleted bovine alpha-lactalbumin made LEthal to tumor cells (BAMLET) by Hoque, Mehboob, Gupta, Jyoti, Rabbani, Gulam, Khan, Rizwan Hasan, Saleemuddin, M

“…Oleic acid (OA) complexes of human alpha-lactalbumin (α-LA) and several other proteins are effective in the killing of a variety of tumor cells. While debate…”
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Partially Folded State of Ovalbumin at Low pH Tends to Aggregate by Naeem, Aabgeena, Khan, Taqi Ahmed, Muzaffar, Mohammad, Ahmad, Saman, Saleemuddin, M

“…At pH 2, ovalbumin retains native-like secondary structure as seen by far-UV CD and FTIR, but lacks well-defined tertiary structure as seen by the fluorescence…”
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Plasma beads loaded with Candida albicans cytosolic proteins impart protection against the fungal infection in BALB/c mice by Ahmad, Ejaj, Fatima, Munazza T, Saleemuddin, M, Owais, M

“…Highlights ► Development of autologous clotted plasma-based beads as an antigen delivery system. ► Plasma bead entrapped Candida cytosolic proteins evoke…”
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Antibacterial efficacy of Withania somnifera (ashwagandha) an indigenous medicinal plant against experimental murine salmonellosis by Owais, M., Sharad, K.S., Shehbaz, A., Saleemuddin, M.

“…In the present study, we evaluated the antibacterial activity of ashwagandha [ Withania somnifera L. Dunal (Solanaceae; root and leaves)], an Indian…”
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Bioaffinity based immobilization of enzymes by Saleemuddin, M

“…Procedures that utilize the affinities of biomolecules and ligands for the immobilization of enzymes are gaining increasing acceptance in the construction of…”
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Partially Folded Glycated State of Human Serum Albumin Tends to Aggregate by Khan, Taqi Ahmed, Saleemuddin, M., Naeem, Aabgeena

“…The interaction of reducing carbohydrates with proteins leads to a cascade of reactions that are known as glycation or Maillard reactions that results in the…”
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Bioaffinity based oriented immobilization of stem bromelain by GUPTA, Pawan, SALEEMUDDIN, M

“…Bromelain is a basic, 23.8 kDa thiol proteinase obtained from stem of the pineapple plant (Ananas comosus) and is unique in containing a single oligosaccharide…”
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Oriented immobilization of stem bromelain via the lone histidine on a metal affinity support by Gupta, Pawan, Maqbool, Tariq, Saleemuddin, M.

“…Bromelain is a basic, 23.8 kDa thiol proteinase obtained from the stem of the pineapple plant ( Ananas comosus) and is unique for it contains a single…”
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Glycoprotein targeting and other applications of lectins in biotechnology by Naeem, Aabgeena, Saleemuddin, M, Khan, Rizwan Hasan

“…Glycoconjugates comprise a variety of structures, include glycoproteins and glycolipids and are found on the surfaces of animal and plant cells, as well as on…”
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Immunoglobulin glycation with fructose: A comparative study by Jairajpuri, Deeba S., Fatima, Shamila, Saleemuddin, M.

“…Immunoglobulins undergo non-enzymatic glycation reaction with sugars both in vivo and in vitro. Effects of glycation on the ability of the antibodies to bind…”
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Inactivation and modification of superoxide dismutase by glyoxal: Prevention by antibodies by Jabeen, Rukhsana, Saleemuddin, M., Petersen, John, Mohammad, Amin

“…Glyoxal is an endogenous compound, the levels of which are increased in various pathologies associated with hyperglycaemia and other related disorders. It has…”
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Levels of some antioxidant molecules and lipid peroxidation during in vivo transformation of the progenetic metacercaria of Clinostomum complanatum to ovigerous adult worms by Rizvi, Asim, Hasan, Shirin, Alam, Maroof, Zafar, Atif, Fatima, Tasneem, Shareef, P.A.A., Banu, Naheed, Saleemuddin, M., Saifullah, Mohammad K., Abidi, S. M.A.

“…The levels of oxidative stress markers are an important indicator of the physiological state of the parasite and its host. In the present study levels of lipid…”
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Additional stabilization of stem bromelain coupled to a thermosensitive polymer by uniform orientation and using polyclonal antibodies by Mahmood, Rubab, Saleemuddin, M

“…Stem bromelain was covalently coupled to a thermosensitive polymer of N-isopropylacrylamide (p(NIPAm)) either through the amino groups of the enzyme (randomly…”
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A rabbit eye model for in vivo transformation of progenetic metacercariae of Clinostomum complanatum into ovigerous adult worms by Rizvi, A, Zaidi, Z A, Alam, M M, Zafar, A, Shareef, P A A, Saifullah, M K, Saleemuddin, M, Abidi, S M A

“…Clinostomum complanatum is a digenetic trematode that causes yellow grub disease in some fish species and also shows zoonotic potential by sporadically…”
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Polyclonal antibodies inhibit the glycation-induced inactivation of bovine Cu,Zn-superoxide dismutase by Jabeen, Rukhsana, Saleemuddin, M.

“…In vitro incubation of bovine Cu,Zn‐SOD (Cu,Zn‐superoxide dismutase) with glucose, ribose or fructose results in a remarkable inactivation of the enzyme. There…”
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Trifluoroethanol-induced “molten globule” state in stem bromelain by Gupta, Pawan, Khan, Rizwan H., Saleemuddin, M.

“…2,2,2-Trifluoroethanol (TFE) denatures proteins but also stabilizes/induces α helical conformation in partially/completely unfolded proteins. As reported…”
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