Search Results - "Saldi, Tassa K"
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TDP-1, the Caenorhabditis elegans ortholog of TDP-43, limits the accumulation of double-stranded RNA
Published in The EMBO journal (17-12-2014)“…Caenorhabditis elegans mutants deleted for TDP‐1, an ortholog of the neurodegeneration‐associated RNA‐binding protein TDP‐43, display only mild phenotypes…”
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Journal Article -
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Saliva TwoStep for rapid detection of asymptomatic SARS-CoV-2 carriers
Published in eLife (29-03-2021)“…Here, we develop a simple molecular test for SARS-CoV-2 in saliva based on reverse transcription loop-mediated isothermal amplification. The test has two…”
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Just 2% of SARS-CoV-2—positive individuals carry 90% of the virus circulating in communities
Published in Proceedings of the National Academy of Sciences - PNAS (25-05-2021)“…We analyze data from the fall 2020 pandemic response efforts at the University of Colorado Boulder, where more than 72,500 saliva samples were tested for…”
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The Caenorhabditis elegans Ortholog of TDP-43 Regulates the Chromatin Localization of the Heterochromatin Protein 1 Homolog HPL-2
Published in Molecular and cellular biology (01-08-2018)“…TDP-1 is the Caenorhabditis elegans ortholog of mammalian TDP-43, which is strongly implicated in the etiology of frontotemporal dementia (FTD) and amyotrophic…”
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Higher Viral Load Drives Infrequent Severe Acute Respiratory Syndrome Coronavirus 2 Transmission Between Asymptomatic Residence Hall Roommates
Published in The Journal of infectious diseases (28-10-2021)“…Abstract Background The coronavirus disease 2019 pandemic spread to >200 countries in <6 months. To understand coronavirus spread, determining transmission…”
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Neurodegeneration, Heterochromatin, and Double-Stranded RNA
Published in Journal of Experimental Neuroscience (2019)“…Changes in chromatin and epigenetic modifications have been associated with aging and aging-associated neurodegenerative diseases, although the causal…”
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Book Review Journal Article -
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Cell Death by Glutamine Repeats?
Published in Science (American Association for the Advancement of Science) (24-02-2012)“…A glutamine-rich protein plays a role in developmentally regulated cell death in C. elegans . A number of eukaryotic proteins contain stretches of repeating…”
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Structure/function analysis of TDP-43 neurotoxicity in C. elegans
Published in Alzheimer's & dementia (01-07-2010)Get full text
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TDP ‐1, the C aenorhabditis elegans ortholog of TDP ‐43, limits the accumulation of double‐stranded RNA
Published in The EMBO journal (17-12-2014)“…Caenorhabditis elegans mutants deleted for TDP ‐1, an ortholog of the neurodegeneration‐associated RNA ‐binding protein TDP ‐43, display only mild phenotypes…”
Get full text
Journal Article -
10
Development. Cell death by glutamine repeats?
Published in Science (American Association for the Advancement of Science) (24-02-2012)Get full text
Journal Article -
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O1‐07‐03: Structure/function analysis of TDP‐43 neurotoxicity in C. elegans
Published in Alzheimer's & dementia (01-07-2010)Get full text
Journal Article