Search Results - "Salazar, Ramon Ramon"

Personalizing colon cancer adjuvant therapy: selecting optimal treatments for individual patients by Dienstmann, Rodrigo, Salazar, Ramon, Tabernero, Josep

“…For more than three decades, postoperative chemotherapy-initially fluoropyrimidines and more recently combinations with oxaliplatin-has reduced the risk of…”
Get full text

Analysing black phosphorus transistors using an analytic Schottky barrier MOSFET model by Penumatcha, Ashish V., Salazar, Ramon B., Appenzeller, Joerg

“…Owing to the difficulties associated with substitutional doping of low-dimensional nanomaterials, most field-effect transistors built from carbon nanotubes,…”
Get full text

Toward Low-Power Electronics: Tunneling Phenomena in Transition Metal Dichalcogenides by Das, Saptarshi, Prakash, Abhijith, Salazar, Ramon, Appenzeller, Joerg

“…In this article, we explore, experimentally, the impact of band-to-band tunneling on the electronic transport of double-gated WSe2 field-effect transistors…”
Get full text

Unresponsiveness of colon cancer to BRAF(V600E) inhibition through feedback activation of EGFR by Prahallad, Anirudh, Sun, Chong, Huang, Sidong, Di Nicolantonio, Federica, Salazar, Ramon, Zecchin, Davide, Beijersbergen, Roderick L., Bardelli, Alberto, Bernards, René

“…Inhibition of activated BRAF has been ineffective in colon cancers with the mutation; here, this is shown to be due to the feedback activation of the epidermal…”
Get full text

From Fowler-Nordheim to Nonequilibrium Green's Function Modeling of Tunneling by Ilatikhameneh, Hesameddin, Salazar, Ramon B., Klimeck, Gerhard, Rahman, Rajib, Appenzeller, Joerg

“…In this paper, an analytic model is proposed, which provides, in a continuous manner, the current-voltage (<inline-formula> <tex-math notation="LaTeX">I…”
Get full text

Discovery and validation of new potential biomarkers for early detection of colon cancer by Solé, Xavier, Crous-Bou, Marta, Cordero, David, Olivares, David, Guinó, Elisabet, Sanz-Pamplona, Rebeca, Rodriguez-Moranta, Francisco, Sanjuan, Xavier, de Oca, Javier, Salazar, Ramon, Moreno, Victor

“…Accurate detection of characteristic proteins secreted by colon cancer tumor cells in biological fluids could serve as a biomarker for the disease. The aim of…”
Get full text

Colorectal cancer intrinsic subtypes predict chemotherapy benefit, deficient mismatch repair and epithelial‐to‐mesenchymal transition by Roepman, Paul, Schlicker, Andreas, Tabernero, Josep, Majewski, Ian, Tian, Sun, Moreno, Victor, Snel, Mireille H, Chresta, Christine M, Rosenberg, Robert, Nitsche, Ulrich, Macarulla, Teresa, Capella, Gabriel, Salazar, Ramon, Orphanides, George, Wessels, Lodewyk FA, Bernards, Rene, Simon, Iris M

“…In most colorectal cancer (CRC) patients, outcome cannot be predicted because tumors with similar clinicopathological features can have differences in disease…”
Get full text

A Phase 1 Trial of Oncolytic Adenovirus ICOVIR-5 Administered Intravenously to Cutaneous and Uveal Melanoma Patients by García, Margarita, Moreno, Rafael, Gil-Martin, Marta, Cascallò, Manel, de Olza, Maria Ochoa, Cuadra, Carmen, Piulats, Josep Maria, Navarro, Valentin, Domenech, Marta, Alemany, Ramon, Salazar, Ramon

“…Oncolytic viruses represent a unique type of agents that combine self-amplification, lytic, and immunostimulatory properties against tumors. A local and…”
Get more information

Optimizing Anti-EGFR Therapy in Colorectal Cancer by Salazar, Ramon, Ciardiello, Fortunato

“…Treatment with anti-EGFR monoclonal antibodies has been successfully integrated in the continuum of care for metastatic colorectal cancer. The major challenge…”
Get full text

Gene Expression Signature to Improve Prognosis Prediction of Stage II and III Colorectal Cancer by SALAZAR, Ramon, ROEPMAN, Paul, BRUIN, Sjoerd, KERR, David, KUPPEN, Peter, VAN DE VELDE, Cornelis, MORREAU, Hans, VAN VELTHUYSEN, Loes, GLAS, Annuska M, VAN'T VEER, Laura J, TOLLENAAR, Rob, CAPELLA, Gabriel, MORENO, Victor, SIMON, Iris, DREEZEN, Christa, LOPEZ-DORIGA, Adriana, SANTOS, Cristina, MARIJNEN, Corrie, WESTERGA, Johan

“…This study aims to develop a robust gene expression classifier that can predict disease relapse in patients with early-stage colorectal cancer (CRC). Fresh…”
Get full text

Oxaliplatin, fluorouracil, and leucovorin with or without cetuximab in patients with resected stage III colon cancer (PETACC-8): an open-label, randomised phase 3 trial by Taieb, Julien, Prof, Tabernero, Josep, Prof, Mini, Enrico, Prof, Subtil, Fabien, PhD, Folprecht, Gunnar, MD, Van Laethem, Jean-Luc, Prof, Thaler, Josef, Prof, Bridgewater, John, MD, Petersen, Lone Nørgård, Prof, Blons, Hélène, PhD, Collette, Laurence, PhD, Van Cutsem, Eric, Prof, Rougier, Philippe, Prof, Salazar, Ramon, Prof, Bedenne, Laurent, Prof, Emile, Jean-François, Prof, Laurent-Puig, Pierre, Prof, Lepage, Come, Prof

“…Summary Background Since the 1990s, fluorouracil-based adjuvant chemotherapy has significantly reduced the risk of tumour recurrence in patients with stage III…”
Get full text

Bevacizumab plus oxaliplatin-based chemotherapy as adjuvant treatment for colon cancer (AVANT): a phase 3 randomised controlled trial by de Gramont, Aimery, Prof, Van Cutsem, Eric, Prof, Schmoll, Hans-Joachim, Prof, Tabernero, Josep, MD, Clarke, Stephen, Prof, Moore, Malcolm J, Prof, Cunningham, David, Prof, Cartwright, Thomas H, MD, Hecht, J Randolph, Prof, Rivera, Fernando, MD, Im, Seock-Ah, Prof, Bodoky, György, Prof, Salazar, Ramon, Prof, Maindrault-Goebel, Frédérique, MD, Shacham-Shmueli, Einat, MD, Bajetta, Emilio, Prof, Makrutzki, Martina, MD, Shang, Aijing, MD, André, Thierry, MD, Hoff, Paulo M, Prof

“…Summary Background Bevacizumab improves the efficacy of oxaliplatin-based chemotherapy in metastatic colorectal cancer. Our aim was to assess the use of…”
Get full text

Intratumor CMS Heterogeneity Impacts Patient Prognosis in Localized Colon Cancer by Marisa, Laetitia, Blum, Yuna, Taieb, Julien, Ayadi, Mira, Pilati, Camilla, Le Malicot, Karine, Lepage, Côme, Salazar, Ramon, Aust, Daniela, Duval, Alex, Blons, Hélène, Taly, Valérie, Gentien, David, Rapinat, Audrey, Selves, Janick, Mouillet-Richard, Sophie, Boige, Valérie, Emile, Jean-François, de Reyniès, Aurélien, Laurent-Puig, Pierre

“…The consensus molecular subtypes (CMS) represent a significant advance in the understanding of intertumor heterogeneity in colon cancer. Intratumor…”
Get full text

Cediranib With mFOLFOX6 Versus Bevacizumab With mFOLFOX6 As First-Line Treatment for Patients With Advanced Colorectal Cancer: A Double-Blind, Randomized Phase III Study (HORIZON III) by SCHMOLL, Hans-Joachim, CUNNINGHAM, David, SALAZAR, Ramon, BARKER, Peter, MOOKERJEE, Bijoyesh, ROBERTSON, Jane, VAN CUTSEM, Eric, SOBRERO, Alberto, KARAPETIS, Christos S, ROUGIER, Philippe, KOSKI, Sheryl L, KOCAKOVA, Ilona, BONDARENKO, Igor, BODOKY, György, MAINWARING, Paul

“…To compare the efficacy of cediranib (a vascular endothelial growth factor receptor tyrosine kinase inhibitor [VEGFR TKI]) with that of bevacizumab…”
Get full text

Genomic Classifier ColoPrint Predicts Recurrence in Stage II Colorectal Cancer Patients More Accurately Than Clinical Factors by Kopetz, Scott, Tabernero, Josep, Rosenberg, Robert, Jiang, Zhi‐Qin, Moreno, Víctor, Bachleitner‐Hofmann, Thomas, Lanza, Giovanni, Stork‐Sloots, Lisette, Maru, Dipen, Simon, Iris, Capellà, Gabriel, Salazar, Ramon

“…Background. Approximately 20% of patients with stage II colorectal cancer will experience a relapse. Current clinical‐pathologic stratification factors do not…”
Get full text

Random Forest Modeling of Acute Toxicity in Anal Cancer: Effects of Peritoneal Cavity Contouring Approaches on Model Performance by Salazar, Ramon M, Duryea, Jack D, Leone, Alexandra O, Nair, Saurabh S, Mumme, Raymond P, De, Brian, Corrigan, Kelsey L, Rooney, Michael K, Das, Prajnan, Holliday, Emma B, Court, Laurence E, Niedzielski, Joshua S

“…Our purpose was to analyze the effect on gastrointestinal (GI) toxicity models when their dose-volume metrics predictors are derived from segmentations of the…”
Get full text

Phase 1 study of intravenous administration of the chimeric adenovirus enadenotucirev in patients undergoing primary tumor resection by Garcia-Carbonero, Rocio, Salazar, Ramon, Duran, Ignacio, Osman-Garcia, Ignacio, Paz-Ares, Luis, Bozada, Juan M, Boni, Valentina, Blanc, Christine, Seymour, Len, Beadle, John, Alvis, Simon, Champion, Brian, Calvo, Emiliano, Fisher, Kerry

“…Enadenotucirev (formerly ColoAd1) is a tumor-selective chimeric adenovirus with demonstrated preclinical activity. This phase 1 Mechanism of Action study…”
Get full text

Gastroenteropancreatic neuroendocrine tumours by Modlin, Irvin M, Prof, Oberg, Kjell, Prof, Chung, Daniel C, MD, Jensen, Robert T, MD, de Herder, Wouter W, MD, Thakker, Rajesh V, Prof, Caplin, Martyn, MD, Delle Fave, Gianfranco, Prof, Kaltsas, Greg A, MD, Krenning, Eric P, Prof, Moss, Steven F, MD, Nilsson, Ola, Prof, Rindi, Guido, MD, Salazar, Ramon, MD, Ruszniewski, Philippe, Prof, Sundin, Anders, MD

“…Summary Gastroenteropancreatic (GEP) neuroendocrine tumours (NETs) are fairly rare neoplasms that present many clinical challenges. They secrete peptides and…”
Get full text

A phase 1 dose escalation study of the oncolytic adenovirus enadenotucirev, administered intravenously to patients with epithelial solid tumors (EVOLVE) by Machiels, Jean-Pascal, Salazar, Ramon, Rottey, Sylvie, Duran, Ignacio, Dirix, Luc, Geboes, Karen, Wilkinson-Blanc, Christine, Pover, Gillian, Alvis, Simon, Champion, Brian, Fisher, Kerry, McElwaine-Johnn, Hilary, Beadle, John, Calvo, Emiliano

“…Enadenotucirev is a chimeric adenovirus with demonstrated preclinical tumor-selective cytotoxicity and a short half-life. Further clinical mechanism of action…”
Get full text

Identification of candidate susceptibility genes for colorectal cancer through eQTL analysis by Closa, Adria, Cordero, David, Sanz-Pamplona, Rebeca, Solé, Xavier, Crous-Bou, Marta, Paré-Brunet, Laia, Berenguer, Antoni, Guino, Elisabet, Lopez-Doriga, Adriana, Guardiola, Jordi, Biondo, Sebastiano, Salazar, Ramon, Moreno, Victor

“…In this study, we aim to identify the genes responsible for colorectal cancer risk behind the loci identified in genome-wide association studies (GWAS). These…”
Get full text