Search Results - "Salas, Sébastien"

A Prognostic Nomogram for Prediction of Recurrence in Desmoid Fibromatosis by Crago, Aimeé M, Denton, Brian, Salas, Sébastien, Dufresne, Armelle, Mezhir, James J, Hameed, Meera, Gonen, Mithat, Singer, Samuel, Brennan, Murray F

“…OBJECTIVE:To construct a postoperative nomogram to estimate the risk of local recurrence for patients with desmoid tumors. BACKGROUND:The standard management…”
Get full text

A subset of epithelioid and spindle cell rhabdomyosarcomas is associated with TFCP2 fusions and common ALK upregulation by Le Loarer, François, Cleven, Arjen H. G., Bouvier, Corinne, Castex, Marie-Pierre, Romagosa, Cleofe, Moreau, Anne, Salas, Sébastien, Bonhomme, Benjamin, Gomez-Brouchet, Anne, Laurent, Camille, Le Guellec, Sophie, Audard, Virginie, Giraud, Antoine, Ramos-Oliver, Irma, Cleton-Jansen, Anne-Marie, Savci-Heijink, Dilara C., Kroon, Herman M., Baud, Jessica, Pissaloux, Daniel, Pierron, Gaëlle, Sherwood, Anand, Coindre, Jean Michel, Bovée, Judith V. M. G., Larousserie, Frédérique, Tirode, Franck

“…Rhabdomyosarcomas with TFCP2 fusions represent an emerging subtype of tumors, initially discovered by RNA-sequencing. We report herein the clinicopathological,…”
Get full text

Prognostic Factors Influencing Progression-Free Survival Determined From a Series of Sporadic Desmoid Tumors: A Wait-and-See Policy According to Tumor Presentation by SALAS, Sébastien, DUFRESNE, Armelle, OBERLIN, Odile, BROUSTE, Véronique, COINDRE, Jean-Michel, BUI, Binh, BLAY, Jean-Yves, TERRIER, Philippe, RANCHERE-VINCE, Dominique, BONVALOT, Sylvie, STOECKLE, Eberhard, GUILLOU, Louis, LE CESNE, Axel

“…Desmoid tumors are mesenchymal fibroblastic/myofibroblastic proliferations with locoregional aggressiveness and high ability to recur after initial treatment…”
Get full text

Nutritional Factors during and after Cancer: Impacts on Survival and Quality of Life by Salas, Sébastien, Cottet, Vanessa, Dossus, Laure, Fassier, Philippine, Ginhac, Julie, Latino-Martel, Paule, Romieu, Isabelle, Schneider, Stéphane, Srour, Bernard, Touillaud, Marina, Touvier, Mathilde, Ancellin, Raphaëlle

“…The French National Cancer Institute conducted a collective expertise study with researchers and clinical experts from the French Network for Nutrition And…”
Get full text

Surgical versus non-surgical approach in primary desmoid-type fibromatosis patients: A nationwide prospective cohort from the French Sarcoma Group by Penel, Nicolas, Le Cesne, Axel, Bonvalot, Sylvie, Giraud, Antoine, Bompas, Emmanuelle, Rios, Maria, Salas, Sébastien, Isambert, Nicolas, Boudou-Rouquette, Pascaline, Honore, Charles, Italiano, Antoine, Ray-Coquard, Isabelle, Piperno-Neumann, Sophie, Gouin, François, Bertucci, François, Ryckewaert, Thomas, Kurtz, Jean-Emmanuel, Ducimetiere, Françoise, Coindre, Jean-Michel, Blay, Jean-Yves

“…The outcome of desmoid-type fibromatosis (DTF) is unpredictable. Currently, a wait-and-see approach tends to replace large en bloc resection as the first…”
Get full text

Validated prediction of clinical outcome in sarcomas and multiple types of cancer on the basis of a gene expression signature related to genome complexity by Lucchesi, Carlo, de Reynies, Aurélien, Brouste, Véronique, Coindre, Jean-Michel, Blay, Jean-Yves, Bui, Binh, Salas, Sébastien, Chibon, Frédéric, Terrier, Philippe, Vince-Ranchère, Dominique, Guillou, Louis, Pérot, Gaëlle, Tirode, Franck, Kauffmann, Audrey, Bonvalot, Sylvie, Aurias, Alain, Collin, Françoise, Leroux, Agnès, Le Cesne, Axel, Lagarde, Pauline

“…A prognostic gene expression signature predicts metastasis in individuals with sarcomas and other tumor types more accurately than existing tools. Sarcomas are…”
Get full text

Surgical Margins and Adjuvant Therapies in Malignant Phyllodes Tumors of the Breast: A Multicenter Retrospective Study by Neron, Mathias, Sajous, Christophe, Thezenas, Simon, Piperno-Neumann, Sophie, Reyal, Fabien, Laé, Marick, Chakiba, Camille, Michot, Audrey, Penel, Nicolas, Honoré, Charles, Owen, Clémentine, Bertucci, François, Salas, Sébastien, Saada-Bouzid, Esma, Valentin, Thibaud, Bompas, Emmanuelle, Brahmi, Mehdi, Ray-Coquard, Isabelle, Blay, Jean-Yves, Firmin, Nelly

“…Background The optimal threshold of surgical margins for breast malignant phyllodes tumors (MPTs) and the impact of adjuvant chemotherapy and radiotherapy were…”
Get full text

Bintrafusp alfa, a bifunctional fusion protein targeting TGF-β and PD-L1, in patients with human papillomavirus-associated malignancies by Strauss, Julius, Gatti-Mays, Margaret E, Cho, Byoung Chul, Hill, Andrew, Salas, Sébastien, McClay, Edward, Redman, Jason M, Sater, Houssein A, Donahue, Renee N, Jochems, Caroline, Lamping, Elizabeth, Burmeister, Andrea, Marté, Jennifer L, Cordes, Lisa M, Bilusic, Marijo, Karzai, Fatima, Ojalvo, Laureen S, Jehl, Genevieve, Rolfe, P Alexander, Hinrichs, Christian S, Madan, Ravi A, Schlom, Jeffrey, Gulley, James L

“…BackgroundBintrafusp alfa is a first-in-class bifunctional fusion protein composed of the extracellular domain of transforming growth factor (TGF)-βRII (a…”
Get full text

Impact on Health‐Related Quality of Life of Parenteral Nutrition for Patients with Advanced Cancer Cachexia: Results from a Randomized Controlled Trial by Bouleuc, Carole, Anota, Amélie, Cornet, Cécile, Grodard, Ghislain, Thiery‐Vuillemin, Antoine, Dubroeucq, Olivier, Crétineau, Nathalie, Frasie, Véronique, Gamblin, Vincent, Chvetzoff, Gisèle, Favier, Laure, Tournigand, Christophe, Grach, Marie‐Christine, Raynard, Bruno, Salas, Sébastien, Capodano, Géraldine, Pazart, Lionel, Aubry, Régis

“…Background Malnutrition worsens health‐related quality of life (HRQoL) and the prognosis of patients with advanced cancer. This study aimed to assess the…”
Get full text

Safety and efficacy of regorafenib in patients with advanced soft tissue sarcoma (REGOSARC): a randomised, double-blind, placebo-controlled, phase 2 trial by Mir, Olivier, MD, Brodowicz, Thomas, MD, Italiano, Antoine, MD, Wallet, Jennifer, MSc, Blay, Jean-Yves, MD, Bertucci, François, MD, Chevreau, Christine, MD, Piperno-Neumann, Sophie, MD, Bompas, Emmanuelle, MD, Salas, Sébastien, MD, Perrin, Christophe, MD, Delcambre, Corinne, MD, Liegl-Atzwanger, Bernadette, MD, Toulmonde, Maud, MD, Dumont, Sarah, MD, Ray-Coquard, Isabelle, MD, Clisant, Stéphanie, PharmD, Taieb, Sophie, MD, Guillemet, Cécile, MD, Rios, Maria, MD, Collard, Olivier, MD, Bozec, Laurence, MD, Cupissol, Didier, MD, Saada-Bouzid, Esma, MD, Lemaignan, Christine, MD, Eisterer, Wolfgang, MD, Isambert, Nicolas, MD, Chaigneau, Loïc, MD, Cesne, Axel Le, MD, Penel, Nicolas, Dr

“…Summary Background Regorafenib is a multikinase inhibitor with proven activity in refractory gastrointestinal stromal tumours and chemotherapy-refractory…”
Get full text

TOP3A amplification and ATRX inactivation are mutually exclusive events in pediatric osteosarcomas using ALT by de Nonneville, Alexandre, Salas, Sébastien, Bertucci, François, Sobinoff, Alexander P, Adélaïde, José, Guille, Arnaud, Finetti, Pascal, Noble, Jane R, Churikov, Dimitri, Chaffanet, Max, Lavit, Elise, Pickett, Hilda A, Bouvier, Corinne, Birnbaum, Daniel, Reddel, Roger R, Géli, Vincent

“…In some types of cancer, telomere length is maintained by the alternative lengthening of telomeres (ALT) mechanism. In many ALT cancers, the…”
Get full text

Lack of prognostic value of CTNNB1 mutation profile in desmoid-type fibromatosis by Penel, Nicolas, Bonvalot, Sylvie, Bimbai, Andre-Michel, Meurgey, Alexandra, Le Loarer, François, Salas, Sebastien, Piperno-Neumann, Sophie, Chevreau, Christine, Boudou-Rouquette, Pascaline, Dubray-Longeras, Pascale, Kurtz, Jean-Emmanuel, Guillemet, Cecile, Bompas, Emmanuelle, Italiano, Antoine, Le Cesne, Axel, Orbach, Daniel, Thery, Julien, Le Deley, Marie-Cécile, Blay, Jean-Yves, Mir, Olivier

“…This prospective nationwide cohort study aimed to investigate desmoid-type fibromatosis (DF) outcomes, focusing on the prognostic value of CTNNB1 mutations…”
Get full text

Impact of Metastasis Surgery and Alkylating-Agent-Based Chemotherapy on Outcomes of Metastatic Malignant Phyllodes Tumors: A Multicenter Retrospective Study by Neron, Mathias, Sajous, Christophe, Thezenas, Simon, Piperno-Neumann, Sophie, Reyal, Fabien, Laé, Marick, Chakiba, Camille, Penel, Nicolas, Ryckewaert, Thomas, Honoré, Charles, Bertucci, François, Monneur, Audrey, Salas, Sébastien, Duffaud, Florence, Saada-Bouzid, Esma, Isambert, Nicolas, Brahmi, Mehdi, Ray-Coquard, Isabelle, Blay, Jean-Yves, Firmin, Nelly

“…Background Metastatic phyllodes tumors have poor prognosis with median overall survival of 11.5 months. The objective of this study is to identify prognostic…”
Get full text

Phase II Study to Determine the Antitumor Activity and Safety of Simlukafusp Alfa (FAP-IL2v) Combined with Atezolizumab in Esophageal Cancer by Prenen, Hans, Deva, Sanjeev, Keam, Bhumsuk, Lindsay, Colin R., Lugowska, Iwona, Yang, James C., Longo, Federico, de Miguel, Maria, Ponz-Sarvise, Mariano, Ahn, Myung-Ju, Gumus, Mahmut, Champiat, Stephane, Italiano, Antoine, Salas, Sébastien, Perets, Ruth, Arslan, Cagatay, Cho, Byoung C., Evers, Stefan, Boetsch, Christophe, Marbach, Daniel, Dejardin, David, Sleiman, Nassim, Ardeshir, Caroline, Richard, Muriel, Charo, Jehad, Kraxner, Anton, Keshelava, Nino, Teichgräber, Volker, Moreno, Victor

“…Abstract Purpose: In this study, we report the results from the esophageal squamous cell carcinoma (SCC) cohort of a phase II, noncomparative, basket study…”
Get full text

Machine-Learning Exploration of Exposure-Effect Relationships of Cisplatin in Head and Neck Cancer Patients by Cauvin, Céleste, Bourguignon, Laurent, Carriat, Laure, Mence, Abel, Ghipponi, Pauline, Salas, Sébastien, Ciccolini, Joseph

“…Cisplatin is a pivotal drug in the treatment of head and neck cancer, and personalized dosage should help the preservation of an optimal toxicity-efficacy…”
Get full text

Intensive end-of-life care in acute leukemia from a French national hospital database study (2017-2018) by Salas, Sébastien, Pauly, Vanessa, Damge, Margaux, Orleans, Veronica, Fond, Guillaume, Costello, Régis, Boyer, Laurent, Baumstarck, Karine

“…A better understanding of how the care of acute leukemia patients is managed in the last days of life would help clinicians and health policy makers improve…”
Get full text

Domains of quality of life freely expressed by cancer patients and their caregivers: contribution of the SEIQoL by Hamidou, Zeinab, Baumstarck, Karine, Chinot, Olivier, Barlesi, Fabrice, Salas, Sébastien, Leroy, Tanguy, Auquier, Pascal

“…The purposes of this study, performed on a large sample of cancer patient-caregiver dyads, were: i) to simultaneously investigate, using an individualized…”
Get full text

Bintrafusp alfa, a bifunctional fusion protein targeting TGF-β and PD-L1, in advanced squamous cell carcinoma of the head and neck: results from a phase I cohort by Cho, Byoung Chul, Daste, Amaury, Ravaud, Alain, Salas, Sébastien, Isambert, Nicolas, McClay, Edward, Awada, Ahmad, Borel, Christian, Ojalvo, Laureen S, Helwig, Christoph, Rolfe, P Alexander, Gulley, James L, Penel, Nicolas

“…BackgroundWe report the clinical activity and safety of bintrafusp alfa, a first-in-class bifunctional fusion protein composed of the extracellular domain of…”
Get full text

Therapeutic strategy for advanced stages salivary carcinomas of the tongue: A multicenter REFCOR study by Poissonnet, Valentine, Chabrillac, Emilien, Uro-Coste, Emmanuelle, Woisard, Virginie, Moya-Plana, Antoine, Espitalier, Florent, Castelli, Joel, Dedieu, Thibault, Salas, Sébastien, Garrel, Renaud, Baudouin, Robin, Poissonnet, Gilles, Castain, Claire, Barbut, Jonathan, Mirghani, Haitham, Evrard, Diane, Bouchain, Olivier, Marie, Jean Paul, Orliac, Hélène, Ceruse, Philippe, Dufour, Xavier, Brenet, Esteban, Rambeau, Audrey, Herman, Philippe, Abu Shama, Yazan, Bertolus, Chloé, Atallah, Sarah, Morinière, Sylvain, Righini, Christian, Mouawad, François, Duflo, Suzy, Segier, Bertille, Vergez, Sébastien

“…•Advanced tongue salivary gland carcinomas are less chemo/radiosensitive than SCC.•Their surgical excision is often associated with poor functional…”
Get full text

Survival outcomes, prognostic factors, and effect of adjuvant radiotherapy and prophylactic neck dissection in salivary acinic cell carcinoma: A prospective multicenter REFCOR study of 187 patients by Chatelet, Florian, Ferrand, François Régis, Atallah, Sarah, Thariat, Juliette, Mouawad, François, Fakhry, Nicolas, Malard, Olivier, Even, Caroline, de Monès, Erwan, Uro-Coste, Emmanuelle, Benzerdjeb, Nazim, Hans, Stéphane, Testelin, Sylvie, Mauvais, Olivier, Evrard, Diane, Bastit, Vianney, Salas, Sébastien, Espitalier, Florent, Classe, Marion, Digue, Laurence, Doré, Mélanie, Wong, Stéphanie, Dupin, Charles, Nguyen, France, Bettoni, Jeremie, Lapierre, Ariane, Colin, Emilien, Philouze, Pierre, Vergez, Sébastien, Baujat, Bertrand, Herman, Philippe, Verillaud, Benjamin

“…Acinic cell carcinomas (AciCCs) are malignant tumours of the salivary glands. The aim of this work was to analyse data from the national REFCOR multicenter…”
Get full text