Search Results - "Salas, Nuria Rodriguez"
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The Frequency of Specific KRAS Mutations, and Their Impact on Treatment Choice and Survival, in Patients With Metastatic Colorectal Cancer
Published in The oncologist (Dayton, Ohio) (01-10-2023)“…Abstract Background Patients with metastatic colorectal cancer (mCRC) and KRAS mutations have a poor prognosis, seemingly dependent on the location of the…”
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Vitamin D opposes multilineage cell differentiation induced by Notch inhibition and BMP4 pathway activation in human colon organoids
Published in Cell death & disease (29-04-2024)“…Understanding the mechanisms involved in colonic epithelial differentiation is key to unraveling the alterations causing inflammatory conditions and cancer…”
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Real-World Outcomes in Patients with Metastatic Colorectal Cancer in Spain: The RWD-ACROSS Study
Published in Cancers (01-09-2023)“…The retrospective, observational RWD-ACROSS study analyzed disease characteristics, systemic treatment, and survival in patients with metastatic colorectal…”
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4
Liquid Biopsy in Pancreatic Cancer: Are We Ready to Apply It in the Clinical Practice?
Published in Cancers (20-04-2021)“…Pancreatic ductal adenocarcinoma (PDAC) exhibits the poorest prognosis of all solid tumors, with a 5-year survival of less than 10%. To improve the prognosis,…”
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Clinical relevance of colorectal cancer molecular subtypes
Published in Critical reviews in oncology/hematology (01-01-2017)“…Highlights • The comprehensive study of molecular changes in colorectal cancer identifies potential therapeutic targets. • The integrative analysis of distinct…”
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Total neoadjuvant therapy with or without aflibercept in rectal cancer: 3-year results of GEMCAD-1402
Published in JNCI : Journal of the National Cancer Institute (06-12-2023)“…The results of the Grupo Español Multidisciplinar en Cáncer Digestivo (GEMCAD)-1402 phase II randomized trial suggested that adding aflibercept to modified…”
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Functional proteomics of colon cancer Consensus Molecular Subtypes
Published in British journal of cancer (01-06-2024)“…Background The Colorectal Cancer Subtyping Consortium established four Consensus Molecular Subtypes (CMS) in colorectal cancer: CMS1…”
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8
Breast cancer stem cell hypothesis: clinical relevance (answering breast cancer clinical features)
Published in Clinical & translational oncology (01-06-2010)“…The cancer stem cells hypothesis arises from observation of normal tissue hierarchy and the demonstration of stem cells in normal tissues. Scientists continue…”
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Organoids and Colorectal Cancer
Published in Cancers (28-05-2021)“…Organoids were first established as a three-dimensional cell culture system from mouse small intestine. Subsequent development has made organoids a key system…”
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10
Molecular markers to predict outcome to antiangiogenic therapies in colorectal cancer: Current evidence and future perspectives
Published in Cancer treatment reviews (01-12-2013)“…Abstract Angiogenesis is a universal requirement for the growth of solid tumours beyond the limits of oxygen diffusion from the existing vasculature. The…”
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Cancer predisposing syndrome: a retrospective cohort analysis in a pediatric and multidisciplinary genetic cancer counseling unit
Published in International journal of clinical oncology (01-05-2022)“…Introduction Approximately 10% of pediatric patients with cancer have an inherited, sometimes masked, cancer predisposition syndrome (CPS). Identifying…”
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Prevalence and Distribution of MUTYH Pathogenic Variants, Is There a Relation with an Increased Risk of Breast Cancer?
Published in Cancers (01-01-2024)“…has been implicated in hereditary colonic polyposis and colorectal carcinoma. However, there are conflicting data refgarding its relationship to hereditary…”
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13
Real-world study on microsatellite instability and mismatch repair deficiency testing patterns among patients with metastatic colorectal cancer in Spain
Published in Clinical & translational oncology (01-04-2024)“…Purpose Clinical practice guidelines recommend that all patients with metastatic colorectal cancer (mCRC) should be tested for mismatch repair deficiency…”
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14
Clinical Score to Predict Recurrence in Patients with Stage II and Stage III Colon Cancer
Published in Cancers (29-11-2022)“…Background: The prognosis of patients with stage II and stage III colon cancer is heterogeneous. Clinical and pathological characteristics, such as tumor…”
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Tailored chemotherapy for colorectal cancer peritoneal metastases based on a drug-screening platform in patient-derived organoids: a case report
Published in Journal of gastrointestinal oncology (28-02-2023)“…Peritoneal metastasis from colorectal cancer (CRC) has limited therapeutic options and poor prognosis. Systemic chemotherapy combined with cytoreductive…”
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Sequential RAS mutations evaluation in cell-free DNA of patients with tissue RAS wild-type metastatic colorectal cancer: the PERSEIDA (Cohort 2) study
Published in Clinical & translational oncology (2024)“…Purpose RAS ( KRAS / NRAS ) mutational status on a tumor biopsy is mandatory to guide the best treatment in metastatic colorectal cancer (mCRC). Determining…”
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Early Clinical Experience with Trifluridine/Tipiracil for Refractory Metastatic Colorectal Cancer: The ROS Study
Published in Cancers (08-09-2021)“…Trifluridine/tipiracil is currently approved for metastatic colorectal cancer (mCRC) refractory to available therapies. However, there is no consensus on…”
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Colonic anastomosis and colonic polyp mucosal metastasis of signet ring cell gastric adenocarcinoma
Published in Clinical & translational oncology (01-03-2010)“…The mucosal metastasis of adenocarcinomas located in colonic mucosa is not infrequent. We present a clinical report of a patient diagnosed with a gastric…”
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Clinico-Pathological Features, Outcomes and Impacts of COVID-19 Pandemic on Patients with Early-Onset Colorectal Cancer: A Single-Institution Experience
Published in Cancers (24-08-2023)“…Background: The rising incidence of colorectal cancer (CRC) among young patients is alarming. We aim to characterize the clinico-pathological features and…”
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ΔNp73, TAp73 and Δ133p53 Extracellular Vesicle Cargo as Early Diagnosis Markers in Colorectal Cancer
Published in Cancers (07-05-2021)“…The early diagnosis of colorectal cancer is a key factor in the overall survival of the patients. The actual screening programs include different approaches…”
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