Search Results - "Salardani, Murilo"
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Assessing proteolytic events in bioinformatic reanalysis of public secretome data from melanoma cell lines
Published in Biochemistry and biophysics reports (01-07-2022)“…Autocrine and paracrine signals are of paramount importance in both normal and oncogenic events and the composition of such secreted molecular signals (i.e the…”
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Proteolytic signaling in cancer
Published in Expert review of proteomics (02-12-2023)“…Cancer is a disease of (altered) biological pathways, often driven by somatic mutations and with several implications. Therefore, the identification of…”
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Heterotypic communication as the promoter of phenotypic plasticity of cancer cells: The role of cancer secretomes
Published in Proteomics (Weinheim) (01-12-2023)“…Cellular communication relies on signaling circuits whose statuses are mainly modulated by soluble biomolecules such as carbohydrates, lipids, proteins, and…”
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Mannose-6-Phosphate Isomerase Functional Status Shapes a Rearrangement in the Proteome and Degradome of Mannose-Treated Melanoma Cells
Published in Journal of proteome research (01-11-2024)“…Metabolic reprogramming is a ubiquitous feature of transformed cells, comprising one of the hallmarks of cancer and enabling neoplastic cells to adapt to new…”
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A proteomics-MM/PBSA dual approach for the analysis of SARS-CoV-2 main protease substrate peptide specificity
Published in Peptides (New York, N.Y. : 1980) (01-08-2022)“…The main protease Mpro of SARS-CoV-2 is a well-studied major drug target. Additionally, it has been linked to this virus’ pathogenicity, possibly through…”
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